HitPredict

Interactor 1: F1M4A0 (F1M4A0)
Tight junction protein 1
Gene: Tjp1

Interactor 2: OCLN (Q6P6T5)
Occludin
Gene: OCLN

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	19470647, 22106313
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0045216 - cell-cell junction organization GO:1905605 - positive regulation of blood-brain barrier permeability
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1725 Rn			1 523
+	Mm
		761855 ZO1_MOUSE (6-1725): 0: 776: 95.70		OCLN_MOUSE (1-522): 0: 863: 94.25
+	Hs
		990850 ZO1_HUMAN (6-1725): 0: 776: 90.66		OCLN_HUMAN (1-523): 0: 835: 87.57
+	Hs
		159219 CSKP_HUMAN (216-784): 5.71e-81: 290: 15.34		OCLN_HUMAN (1-523): 0: 835: 87.57
+	Hs
		1084035 MPP7_HUMAN (270-787): 3.95e-78: 272: 14.75		OCLN_HUMAN (1-523): 0: 835: 87.57
+	Hs
		1021504 DLG1_HUMAN (4-93): 2.98e-23: 109: 33.70		OCLN_HUMAN (1-523): 0: 835: 87.57
+	Hs
		1020169 PTN13_HUMAN (8-472): 4.24e-22: 106: 15.77		OCLN_HUMAN (1-523): 0: 835: 87.57
+	Hs
		1084112 DLG5_HUMAN (242-488): 7.56e-17: 89.6: 21.21		OCLN_HUMAN (1-523): 0: 835: 87.57
+	Hs
		1084108 INADL_HUMAN (31-486): 1.38e-14: 81.9: 15.25		OCLN_HUMAN (1-523): 0: 835: 87.57
+	Hs
		1084090 UNC5B_HUMAN (1611-1695): 4.14e-11: 70.1: 44.71		OCLN_HUMAN (1-523): 0: 835: 87.57
+	Hs
		1084226 ZO2_HUMAN (379-589): 2.33e-09: 64.6: 18.83		OCLN_HUMAN (1-523): 0: 835: 87.57
+	Hs
		130127 CSKP_HUMAN (216-784): 5.71e-81: 290: 15.34		ELL2_HUMAN (374-522): 3.25e-45: 170: 28.85