HitPredict

Interactor 1: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Interactor 2: KLRD1 (Q13241)
Natural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94)
Gene: KLRD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	18448674, 18083576
Identification Methods	x-ray crystallography, surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~Lectin_C
Common GO terms	GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 119 Hs			1 179
+	Hs
		520827 HLAC_HUMAN (2-117): 1.04e-46: 155: 19.66		KLRD1_HUMAN (1-179): 3.07e-47: 154: 100.00
+	Hs
		380019 HLAB_HUMAN (2-117): 1.57e-44: 149: 19.66		KLRD1_HUMAN (1-179): 3.07e-47: 154: 100.00
+	Hs
		409463 HLAA_HUMAN (2-116): 1.54e-47: 157: 22.41		CLC4D_HUMAN (2-175): 5.13e-43: 144: 19.15
+	Hs
		520942 HLAC_HUMAN (2-117): 1.04e-46: 155: 19.66		CLC4D_HUMAN (2-175): 5.13e-43: 144: 19.15
+	Hs
		409538 HLAA_HUMAN (2-116): 1.54e-47: 157: 22.41		CLC4A_HUMAN (16-179): 3.45e-41: 140: 22.29
+	Hs
		521048 HLAC_HUMAN (2-117): 1.04e-46: 155: 19.66		CLC4A_HUMAN (16-179): 3.45e-41: 140: 22.29
+	Hs
		719760 HLAF_HUMAN (2-116): 6.37e-46: 152: 25.00		CLC4A_HUMAN (16-179): 3.45e-41: 140: 22.29
+	Hs
		719754 HLAF_HUMAN (2-116): 6.37e-46: 152: 25.00		CLC2D_HUMAN (6-179): 2.48e-41: 139: 25.84
+	Hs
		409536 HLAA_HUMAN (2-116): 1.54e-47: 157: 22.41		CLC4E_HUMAN (4-176): 7.6e-39: 133: 17.30
+	Hs
		520892 HLAC_HUMAN (2-117): 1.04e-46: 155: 19.66		CLC4G_HUMAN (2-177): 9.77e-39: 135: 21.62
+	Hs
		521046 HLAC_HUMAN (2-117): 1.04e-46: 155: 19.66		CLC4E_HUMAN (4-176): 7.6e-39: 133: 17.30
+	Hs
		719719 HLAF_HUMAN (2-116): 6.37e-46: 152: 25.00		CL12B_HUMAN (53-176): 1.48e-38: 134: 32.06
+	Hs
		719759 HLAF_HUMAN (2-116): 6.37e-46: 152: 25.00		CLC4E_HUMAN (4-176): 7.6e-39: 133: 17.30
+	Hs
		380188 HLAB_HUMAN (2-117): 1.57e-44: 149: 19.66		CLC4E_HUMAN (4-176): 7.6e-39: 133: 17.30
+	Hs
		379884 HLAB_HUMAN (2-117): 1.57e-44: 149: 19.66		NKG2A_HUMAN (10-178): 7.02e-37: 128: 31.95
+	Hs
		409464 HLAA_HUMAN (2-116): 1.54e-47: 157: 22.41		CLC2B_HUMAN (50-178): 1.37e-34: 120: 26.72
+	Hs
		607347 HLAG_HUMAN (2-116): 8.65e-45: 149: 22.41		NKG2A_HUMAN (10-178): 7.02e-37: 128: 31.95
+	Hs
		520947 HLAC_HUMAN (2-117): 1.04e-46: 155: 19.66		CLC2B_HUMAN (50-178): 1.37e-34: 120: 26.72
+	Hs
		719730 HLAF_HUMAN (2-116): 6.37e-46: 152: 25.00		CLC2B_HUMAN (50-178): 1.37e-34: 120: 26.72
+	Hs
		607425 HLAG_HUMAN (2-116): 8.65e-45: 149: 22.41		MRC2_HUMAN (73-174): 7.95e-15: 73.5: 19.63