HitPredict

Interactor 1: HLAF (P30511)
HLA class I histocompatibility antigen, alpha chain F (CDA12) (HLA F antigen) (Leukocyte antigen F) (MHC class I antigen F)
Gene: HLA-F

Interactor 2: CLC2B (Q92478)
C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)
Gene: CLEC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~Lectin_C, Lectin_C~MHC_I
Common GO terms	GO:0000139 - Golgi membrane GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 346 Hs			1 149
+	Hs
		409464 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		CLC2B_HUMAN (1-149): 1.68e-43: 141: 100.00
+	Hs
		409536 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		CLC4E_HUMAN (28-146): 8.33e-37: 127: 29.63
+	Hs
		62087 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		KLRG2_HUMAN (2-146): 7.19e-35: 126: 25.66
+	Hs
		409538 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		CLC4A_HUMAN (16-147): 1.35e-34: 122: 23.13
+	Hs
		607347 HLAG_HUMAN (1-335): 3.64e-155: 440: 79.10		NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75
+	Hs
		379884 HLAB_HUMAN (1-345): 5.62e-154: 438: 79.71		NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75
+	Hs
		380188 HLAB_HUMAN (1-345): 5.62e-154: 438: 79.71		CLC4E_HUMAN (28-146): 8.33e-37: 127: 29.63
+	Hs
		520947 HLAC_HUMAN (1-308): 1.08e-147: 422: 80.20		CLC2B_HUMAN (1-149): 1.68e-43: 141: 100.00
+	Hs
		380019 HLAB_HUMAN (1-345): 5.62e-154: 438: 79.71		KLRD1_HUMAN (25-148): 9.98e-33: 115: 26.72
+	Hs
		719754 HLAF_HUMAN (1-346): 3.71e-148: 422: 100.00		CLC2D_HUMAN (3-146): 1.11e-37: 128: 38.07
+	Hs
		521046 HLAC_HUMAN (1-308): 1.08e-147: 422: 80.20		CLC4E_HUMAN (28-146): 8.33e-37: 127: 29.63
+	Hs
		568036 HLAE_HUMAN (17-330): 1.87e-144: 414: 73.57		NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75
+	Hs
		719759 HLAF_HUMAN (1-346): 3.71e-148: 422: 100.00		CLC4E_HUMAN (28-146): 8.33e-37: 127: 29.63
+	Hs
		62089 HLAC_HUMAN (1-308): 1.08e-147: 422: 80.20		KLRG2_HUMAN (2-146): 7.19e-35: 126: 25.66
+	Hs
		520892 HLAC_HUMAN (1-308): 1.08e-147: 422: 80.20		CLC4G_HUMAN (23-149): 6.73e-35: 124: 28.57
+	Hs
		719719 HLAF_HUMAN (1-346): 3.71e-148: 422: 100.00		CL12B_HUMAN (19-146): 4.97e-35: 124: 31.66
+	Hs
		521048 HLAC_HUMAN (1-308): 1.08e-147: 422: 80.20		CLC4A_HUMAN (16-147): 1.35e-34: 122: 23.13
+	Hs
		719760 HLAF_HUMAN (1-346): 3.71e-148: 422: 100.00		CLC4A_HUMAN (16-147): 1.35e-34: 122: 23.13
+	Hs
		520827 HLAC_HUMAN (1-308): 1.08e-147: 422: 80.20		KLRD1_HUMAN (25-148): 9.98e-33: 115: 26.72
+	Hs
		568037 HLAE_HUMAN (17-330): 1.87e-144: 414: 73.57		NKG2C_HUMAN (6-148): 6.11e-34: 120: 24.20