Protein: ACINU
Apoptotic chromatin condensation inducer in the nucleus (Acinus)

Gene: ACINU, ACIN1
Organism: Homo sapiens
Interactions: 236
UniProt ID: Q9UKV3

Gene Ontology (top 5):
GO:0003676 - nucleic acid binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

127890

SAP18
Histone deacetylase complex subunit SAP18

4

3

Small-scale

0.908

High

1070689

RNPS1
RNA-binding protein with serine-rich domain 1

4

19

Small-scale

0.898

High

641976

U2AF2
Splicing factor U2AF 65 kDa subunit

4

16

High-throughput

0.895

High

963285

U2AF1
Splicing factor U2AF 35 kDa subunit

2

1

High-throughput

0.811

High

1020348

ELAV2
ELAV-like protein 2

2

8

High-throughput

0.811

High

727090

FUS
RNA-binding protein FUS

2

20

High-throughput

0.789

High

1054659

RBM39
RNA-binding protein 39

2

14

Small-scale

0.789

High

943016

SRPK2
SRSF protein kinase 2

4

20

Small-scale

0.701

High

833990

CLK2
Dual specificity protein kinase CLK2

4

17

High-throughput

0.699

High

1356603

LC7L2
Putative RNA-binding protein Luc7-like 2

4

3

High-throughput

0.699

High

1329869

PININ
Pinin

4

4

High-throughput

0.697

High

1251068

SNIP1
Smad nuclear-interacting protein 1

4

2

High-throughput

0.694

High

441391

RU2B
U2 small nuclear ribonucleoprotein B''

1

12

High-throughput

0.691

High

446835

SNRPA
U1 small nuclear ribonucleoprotein A

1

15

High-throughput

0.691

High

453696

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

9

Small-scale

0.691

High

984134

SRS11
Serine/arginine-rich splicing factor 11

1

7

High-throughput

0.691

High

993867

SRSF4
Serine/arginine-rich splicing factor 4

1

11

High-throughput

0.691

High

1029155

SRSF6
Serine/arginine-rich splicing factor 6

1

12

High-throughput

0.691

High

1084448

SRSF7
Serine/arginine-rich splicing factor 7

1

12

High-throughput

0.691

High

1084661

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

10

High-throughput

0.691

High

1288646

PABP5
Polyadenylate-binding protein 5

1

8

High-throughput

0.691

High

1299411

RBM14
RNA-binding protein 14

1

10

High-throughput

0.691

High

1312088

RBM42
RNA-binding protein 42

1

9

High-throughput

0.691

High

1241328

CAMKV
CaM kinase-like vesicle-associated protein

3

3

High-throughput

0.675

High

1302096

SRPK1
SRSF protein kinase 1

3

20

High-throughput

0.675

High

263871

PR40A
Pre-mRNA-processing factor 40 homolog A

3

18

High-throughput

0.667

High

229031

PRKN
E3 ubiquitin-protein ligase parkin

3

16

High-throughput

0.640

High

348200

MYC
Myc proto-oncogene protein

3

14

High-throughput

0.640

High

1354598

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

0

High-throughput

0.638

High

204757

E41L2
Band 4.1-like protein 2

2

11

High-throughput

0.628

High

453931

RU2A
U2 small nuclear ribonucleoprotein A'

2

7

High-throughput

0.628

High

817770

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

1

High-throughput

0.628

High

834143

CLK3
Dual specificity protein kinase CLK3

2

17

High-throughput

0.628

High

948914

SARNP
SAP domain-containing ribonucleoprotein

2

1

High-throughput

0.628

High

1348665

WSB2
WD repeat and SOCS box-containing protein 2

2

11

High-throughput

0.628

High

1356602

E41L3
Band 4.1-like protein 3

2

12

High-throughput

0.628

High

304671

SCAF4
SR-related and CTD-associated factor 4

1

7

High-throughput

0.618

High

442583

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

14

High-throughput

0.618

High

524073

XRCC6
X-ray repair cross-complementing protein 6

1

3

High-throughput

0.618

High

1201201

THOC4
THO complex subunit 4

1

11

Small-scale

0.618

High

1271211

RBP56
TATA-binding protein-associated factor 2N

1

10

High-throughput

0.618

High

1356597

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

5

High-throughput

0.618

High

1356607

RBM8A
RNA-binding protein 8A

1

17

High-throughput

0.618

High

307230

KLHL2
Kelch-like protein 2

2

3

High-throughput

0.611

High

757795

IF4A3
Eukaryotic initiation factor 4A-III

2

17

High-throughput

0.611

High

1046195

DX39B
Spliceosome RNA helicase DDX39B

2

19

High-throughput

0.611

High

1073745

SF3A2
Splicing factor 3A subunit 2

2

5

High-throughput

0.611

High

1343076

LUC7L
Putative RNA-binding protein Luc7-like 1

3

3

High-throughput

0.609

High

1063677

SUZ12
Polycomb protein SUZ12

2

4

High-throughput

0.601

High

1318551

API5
Apoptosis inhibitor 5

2

3

Small-scale

0.601

High

245078

BRD4
Bromodomain-containing protein 4

2

11

High-throughput

0.584

High

683805

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.584

High

809009

YAP1
Transcriptional coactivator YAP1

2

19

Small-scale

0.584

High

905241

1433G
14-3-3 protein gamma

2

20

High-throughput

0.584

High

1059936

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

8

High-throughput

0.584

High

1316808

ACE2
Angiotensin-converting enzyme 2

2

3

High-throughput

0.584

High

1343774

ANLN
Anillin

2

6

High-throughput

0.584

High

900085

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

1

High-throughput

0.578

High

854000

NCBP2
Nuclear cap-binding protein subunit 2

1

12

High-throughput

0.575

High

1172911

NKAP1
Uncharacterized protein NKAPD1

2

1

High-throughput

0.574

High

718295

BMI1
Polycomb complex protein BMI-1

2

11

High-throughput

0.571

High

934551

CSK21
Casein kinase II subunit alpha

1

16

High-throughput

0.569

High

1120490

NCBP3
Nuclear cap-binding protein subunit 3

2

4

High-throughput

0.552

High

1130712

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

9

Small-scale

0.552

High

1346153

ABCF3
ATP-binding cassette sub-family F member 3

1

1

High-throughput

0.541

High

124120

SPT5H
Transcription elongation factor SPT5

1

7

High-throughput

0.536

High

128664

DNM1L
Dynamin-1-like protein

1

3

High-throughput

0.536

High

256594

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

1

High-throughput

0.536

High

268898

SF3B1
Splicing factor 3B subunit 1

1

6

High-throughput

0.536

High

440800

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

5

High-throughput

0.536

High

448850

RU1C
U1 small nuclear ribonucleoprotein C

1

2

High-throughput

0.536

High

449839

HMGB1
High mobility group protein B1

1

18

High-throughput

0.536

High

452913

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.536

High

508768

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.536

High

539182

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

5

High-throughput

0.536

High

739342

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

5

High-throughput

0.536

High

801461

KI67
Proliferation marker protein Ki-67

1

17

High-throughput

0.536

High

824679

MAPK2
MAP kinase-activated protein kinase 2

1

1

High-throughput

0.536

High

827290

ARRB1
Beta-arrestin-1

1

3

High-throughput

0.536

High

831077

CTCF
Transcriptional repressor CTCF

1

3

High-throughput

0.536

High

851728

NEK4
Serine/threonine-protein kinase Nek4

1

6

High-throughput

0.536

High

911993

RUXF
Small nuclear ribonucleoprotein F

1

4

High-throughput

0.536

High

996950

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

1037907

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

19

High-throughput

0.536

High

1039930

SNW1
SNW domain-containing protein 1

1

6

High-throughput

0.536

High

1042815

CUL3
Cullin-3

1

12

High-throughput

0.536

High

1074261

SF3A1
Splicing factor 3A subunit 1

1

7

High-throughput

0.536

High

1092937

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

10

High-throughput

0.536

High

1101026

RN151
RING finger protein 151

1

5

High-throughput

0.536

High

1183253

COX15
Heme A synthase COX15

1

1

High-throughput

0.536

High

1219543

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.536

High

1234450

NKAP
NF-kappa-B-activating protein

1

1

High-throughput

0.536

High

1255915

TBCK
TBC domain-containing protein kinase-like protein

1

5

High-throughput

0.536

High

1288051

HDA11
Histone deacetylase 11

1

12

High-throughput

0.536

High

1290375

RBM33
RNA-binding protein 33

1

9

High-throughput

0.536

High

1312640

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.536

High

1314175

RIOK2
Serine/threonine-protein kinase RIO2

1

2

High-throughput

0.536

High

1331058

E41L1
Band 4.1-like protein 1

1

13

High-throughput

0.536

High

1332225

DEN2D
DENN domain-containing protein 2D

1

2

High-throughput

0.536

High

1347178

ARGL1
Arginine and glutamate-rich protein 1

1

4

High-throughput

0.536

High

1353919

IKBL1
NF-kappa-B inhibitor-like protein 1

1

1

High-throughput

0.536

High

1354148

HDAC6
Histone deacetylase 6

1

10

High-throughput

0.536

High

1356598

SRPK3
SRSF protein kinase 3

1

20

High-throughput

0.536

High

934613

PA1B2
Platelet-activating factor acetylhydrolase IB subunit alpha2

1

0

High-throughput

0.518

High

571242

EGLN
Endoglin

1

0

High-throughput

0.513

High

1199454

LYRIC
Protein LYRIC

1

0

High-throughput

0.513

High

1299440

TECTB
Beta-tectorin

1

0

High-throughput

0.513

High

1356604

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.513

High

902804

SUMO2
Small ubiquitin-related modifier 2

1

4

High-throughput

0.501

High

1290180

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

6

High-throughput

0.489

High

123081

MEN1
Menin

1

4

High-throughput

0.479

High

149408

CTRO
Citron Rho-interacting kinase

1

14

High-throughput

0.479

High

155474

NRP1
Neuropilin-1

1

1

High-throughput

0.479

High

160845

AURKA
Aurora kinase A

1

6

High-throughput

0.479

High

182948

R113A
E3 ubiquitin-protein ligase RNF113A

1

4

High-throughput

0.479

High

210360

PRC1
Protein regulator of cytokinesis 1

1

4

High-throughput

0.479

High

233681

NUPR1
Nuclear protein 1

1

4

High-throughput

0.479

High

256143

OBSL1
Obscurin-like protein 1

1

16

High-throughput

0.479

High

268330

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

298877

UFL1
E3 UFM1-protein ligase 1

1

4

High-throughput

0.479

High

300285

PRP6
Pre-mRNA-processing factor 6

1

5

High-throughput

0.479

High

307863

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

1

3

High-throughput

0.479

High

309541

MTMR5
Myotubularin-related protein 5

1

4

High-throughput

0.479

High

323285

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

16

High-throughput

0.479

High

328995

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

334305

LDHA
L-lactate dehydrogenase A chain

1

2

High-throughput

0.479

High

350667

RASK
GTPase KRas

1

8

High-throughput

0.479

High

360531

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

14

Small-scale

0.479

High

375072

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

380004

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.479

High

385697

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.479

High

422116

LDHB
L-lactate dehydrogenase B chain

1

2

High-throughput

0.479

High

429951

CATL1
Procathepsin L

1

1

High-throughput

0.479

High

438613

HS90B
Heat shock protein HSP 90-beta

1

4

High-throughput

0.479

High

487828

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

504935

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

532645

TCTP
Translationally-controlled tumor protein

1

2

High-throughput

0.479

High

554026

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

570170

CEBPB
CCAAT/enhancer-binding protein beta

1

11

High-throughput

0.479

High

615868

GCSP
Glycine dehydrogenase

1

2

High-throughput

0.479

High

631628

BRD2
Bromodomain-containing protein 2

1

16

High-throughput

0.479

High

652573

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

714600

GRK5
G protein-coupled receptor kinase 5

1

5

High-throughput

0.479

High

721749

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

729703

VGFR2
Vascular endothelial growth factor receptor 2

1

3

High-throughput

0.479

High

738114

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

High-throughput

0.479

High

801972

RECQ1
ATP-dependent DNA helicase Q1

1

9

High-throughput

0.479

High

809476

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

3

High-throughput

0.479

High

824523

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

835559

GSK3A
Glycogen synthase kinase-3 alpha

1

17

High-throughput

0.479

High

841929

CDK9
Cyclin-dependent kinase 9

1

14

High-throughput

0.479

High

877387

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

16

High-throughput

0.479

High

899578

MGN
Protein mago nashi homolog

1

2

High-throughput

0.479

High

903593

WDR5
WD repeat-containing protein 5

1

14

High-throughput

0.479

High

909311

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

8

High-throughput

0.479

High

918122

H4
Histone H4

1

5

High-throughput

0.479

High

932444

ACTC
Actin, alpha cardiac muscle 1

1

9

High-throughput

0.479

High

935361

H31
Histone H3.1

1

13

High-throughput

0.479

High

944988

RED1
Double-stranded RNA-specific editase 1

1

16

High-throughput

0.479

High

970057

KIF23
Kinesin-like protein KIF23

1

12

High-throughput

0.479

High

1018745

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

9

High-throughput

0.479

High

1024443

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

8

High-throughput

0.479

High

1033757

IKZF1
DNA-binding protein Ikaros

1

2

High-throughput

0.479

High

1036193

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

1061674

CUL7
Cullin-7

1

8

High-throughput

0.479

High

1066854

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

1067185

BRD3
Bromodomain-containing protein 3

1

14

High-throughput

0.479

High

1071500

ZMY11
Zinc finger MYND domain-containing protein 11

1

5

Small-scale

0.479

High

1072060

PCBP1
Poly(rC)-binding protein 1

1

7

High-throughput

0.479

High

1080466

EZH2
Histone-lysine N-methyltransferase EZH2

1

13

High-throughput

0.479

High

1081441

E2F4
Transcription factor E2F4

1

6

High-throughput

0.479

High

1086030

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

1189021

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

1191743

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

13

High-throughput

0.479

High

1200744

NAA40
N-alpha-acetyltransferase 40

1

5

High-throughput

0.479

High

1201750

ZCH18
Zinc finger CCCH domain-containing protein 18

1

15

High-throughput

0.479

High

1219394

CUL9
Cullin-9

1

9

Small-scale

0.479

High

1221822

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

1222868

SRRM1
Serine/arginine repetitive matrix protein 1

1

14

High-throughput

0.479

High

1235696

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

5

High-throughput

0.479

High

1244556

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1245226

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

1256471

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1269898

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1286743

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.479

High

1288378

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

20

High-throughput

0.479

High

1300989

CIC
Protein capicua homolog

1

19

High-throughput

0.479

High

1301826

RANB9
Ran-binding protein 9

1

10

High-throughput

0.479

High

1304173

RING2
E3 ubiquitin-protein ligase RING2

1

19

High-throughput

0.479

High

1313215

DDX23
Probable ATP-dependent RNA helicase DDX23

1

11

High-throughput

0.479

High

1315168

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

3

High-throughput

0.479

High

1315539

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

7

High-throughput

0.479

High

1319118

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

5

High-throughput

0.479

High

1331202

SENP3
Sentrin-specific protease 3

1

1

Small-scale

0.479

High

1331596

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

1333799

ECT2
Protein ECT2

1

12

High-throughput

0.479

High

1344159

DDX21
Nucleolar RNA helicase 2

1

13

High-throughput

0.479

High

1344531

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

6

High-throughput

0.479

High

1345456

RAD18
E3 ubiquitin-protein ligase RAD18

1

2

High-throughput

0.479

High

1349032

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

1349900

LUZP4
Leucine zipper protein 4

1

1

Small-scale

0.479

High

1354814

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1356575

IKZF3
Zinc finger protein Aiolos

1

3

High-throughput

0.479

High

1356596

HECD1
E3 ubiquitin-protein ligase HECTD1

1

12

High-throughput

0.479

High

1356599

SRRM2
Serine/arginine repetitive matrix protein 2

1

19

High-throughput

0.479

High

1356601

FBW1A
F-box/WD repeat-containing protein 1A

1

11

High-throughput

0.479

High

1356608

CFA20
Cilia- and flagella-associated protein 20

1

1

High-throughput

0.479

High

268538

BAF
Barrier-to-autointegration factor

1

0

Small-scale

0.458

High

390607

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

397543

ADT2
ADP/ATP translocase 2

1

0

High-throughput

0.458

High

456960

FURIN
Furin

1

0

High-throughput

0.458

High

48747

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.445

High

387708

P53
Cellular tumor antigen p53

1

3

High-throughput

0.445

High

998211

NCBP1
Nuclear cap-binding protein subunit 1

1

3

High-throughput

0.445

High

1032675

CTBP1
C-terminal-binding protein 1

1

4

High-throughput

0.445

High

1044259

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

12

High-throughput

0.445

High

1047312

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

1057713

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

7

High-throughput

0.445

High

1075771

SF01
Splicing factor 1

1

8

High-throughput

0.445

High

1124651

ODFP2
Outer dense fiber protein 2

1

7

High-throughput

0.445

High

1131883

CE170
Centrosomal protein of 170 kDa

1

16

High-throughput

0.445

High

1256627

CE192
Centrosomal protein of 192 kDa

1

1

High-throughput

0.445

High

1270519

HDAC2
Histone deacetylase 2

1

10

High-throughput

0.445

High

1356076

DDX41
Probable ATP-dependent RNA helicase DDX41

1

8

High-throughput

0.445

High

1356600

ITM2B
Integral membrane protein 2B

1

9

High-throughput

0.445

High

787143

AK1C3
Aldo-keto reductase family 1 member C3

1

0

High-throughput

0.438

High

1311123

BTBDA
BTB/POZ domain-containing protein 10

1

0

High-throughput

0.438

High

1172213

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

1174014

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

10

Small-scale

0.437

High

1349961

PHRF1
PHD and RING finger domain-containing protein 1

1

15

High-throughput

0.437

High

1121508

KLH26
Kelch-like protein 26

1

2

High-throughput

0.417

High

89996

D6R9G5
Kelch like family member 2

1

4

High-throughput

0.407

High

1356605

T184B
Transmembrane protein 184B

2

0

High-throughput

0.328

High

1356606

INSL6
Insulin-like peptide INSL6

2

0

High-throughput

0.328

High

1190985

GOGA7
Golgin subfamily A member 7

1

0

High-throughput

0.279

Low

1152446

GRAM4
GRAM domain-containing protein 4

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024