Protein: SCD5
Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (HSCD5) (Stearoyl-CoA 9-desaturase) (Stearoyl-CoA desaturase 2)

Gene: SCD5
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q86SK9

Gene Ontology (top 5):
GO:0004768 - stearoyl-CoA 9-desaturase activity
GO:0005506 - iron ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006636 - unsaturated fatty acid biosynthetic process
GO:0016491 - oxidoreductase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

951234

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.584

High

1286497

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.536

High

182632

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

1098912

KLRD1
Natural killer cells antigen CD94

1

2

High-throughput

0.489

High

48678

ESYT2
Extended synaptotagmin-2

1

2

High-throughput

0.479

High

173974

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

3

High-throughput

0.479

High

417537

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

903978

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

962218

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

1058489

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

1286498

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

1286503

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

1286504

ESYT1
Extended synaptotagmin-1

1

2

High-throughput

0.479

High

1286508

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.479

High

1276187

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1286499

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1286505

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1286506

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1286509

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

1286501

T176A
Transmembrane protein 176A

1

1

High-throughput

0.439

High

130148

PGRC1
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.437

High

293940

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

900890

RAB5C
Ras-related protein Rab-5C

1

1

High-throughput

0.437

High

901355

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.437

High

1004773

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1238723

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

1254438

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1277547

UBE3B
Ubiquitin-protein ligase E3B

1

3

High-throughput

0.437

High

1286493

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

1286494

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.437

High

1286500

TECT2
Tectonic-2

1

3

High-throughput

0.437

High

1286512

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.437

High

653412

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.407

High

870372

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

1

High-throughput

0.407

High

1139477

S39AE
Metal cation symporter ZIP14

1

4

High-throughput

0.407

High

1197810

S39AC
Zinc transporter ZIP12

1

4

High-throughput

0.407

High

1242839

S39A4
Zinc transporter ZIP4

1

4

High-throughput

0.407

High

1286496

CTR3
Cationic amino acid transporter 3

1

2

High-throughput

0.407

High

1286507

S39A8
Metal cation symporter ZIP8

1

4

High-throughput

0.407

High

388134

ACHA
Acetylcholine receptor subunit alpha

1

0

High-throughput

0.279

Low

575672

GPIX
Platelet glycoprotein IX

1

0

High-throughput

0.279

Low

749352

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

1286492

S22A9
Organic anion transporter 7

1

0

High-throughput

0.279

Low

1286513

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.279

Low

487478

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.249

Low

715648

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.249

Low

872481

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

894859

EMD
Emerin

1

0

High-throughput

0.249

Low

1286502

CNDP1
Beta-Ala-His dipeptidase

1

0

High-throughput

0.249

Low

1286510

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1286511

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

256070

S19A2
Thiamine transporter 1

1

0

High-throughput

0.232

Low

339278

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.232

Low

1286495

ZNT7
Zinc transporter 7

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025