Protein: IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA)

Gene: IKKA, Chuk
Organism: Mus musculus
Interactions: 38
UniProt ID: Q60680

Gene Ontology (top 5):
GO:0002011 - morphogenesis of an epithelial sheet
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

291800

NEMO
NF-kappa-B essential modulator

11

20

Small-scale

0.970

High

291460

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

4

19

Small-scale

0.873

High

1141248

IKBB
NF-kappa-B inhibitor beta

3

20

Small-scale

0.845

High

57488

TPX2
Targeting protein for Xklp2

1

4

Small-scale

0.618

High

86490

NLRC5
Protein NLRC5

1

14

Small-scale

0.618

High

1111981

NLRX1
NLR family member X1

1

13

Small-scale

0.618

High

1141249

GIT1
ARF GTPase-activating protein GIT1

1

4

High-throughput

0.590

High

1141259

RAB5A
Ras-related protein Rab-5A

1

8

High-throughput

0.590

High

476818

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

18

High-throughput

0.579

High

956454

NBR1
Next to BRCA1 gene 1 protein

1

5

Small-scale

0.553

High

1141254

SMAD3
Mothers against decapentaplegic homolog 3

1

5

Small-scale

0.536

High

69649

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

2

High-throughput

0.528

High

1112810

TAXB1
Tax1-binding protein 1 homolog

1

20

Small-scale

0.528

High

936786

IRF7
Interferon regulatory factor 7

1

15

Small-scale

0.515

High

799601

CBP
Histone lysine acetyltransferase CREBBP

1

12

Small-scale

0.506

High

485983

ANXA1
Annexin A1

1

8

Small-scale

0.479

High

626859

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

18

Small-scale

0.479

High

648957

TNR5
Tumor necrosis factor receptor superfamily member 5

1

18

Small-scale

0.479

High

956939

SMN
Survival motor neuron protein

1

4

Small-scale

0.479

High

1141257

RNF31
E3 ubiquitin-protein ligase RNF31

1

11

Small-scale

0.479

High

1141260

MTOR
Serine/threonine-protein kinase mTOR

1

20

Small-scale

0.479

High

1141262

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

15

Small-scale

0.479

High

93554

DESP
Desmoplakin

1

20

High-throughput

0.457

High

359437

K1C10
Keratin, type I cytoskeletal 10

1

8

High-throughput

0.457

High

1112107

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

1

High-throughput

0.457

High

1141252

KI20B
Kinesin-like protein KIF20B

1

10

High-throughput

0.457

High

1141258

ANX13
Annexin A13

1

8

High-throughput

0.457

High

1141261

TRI44
Tripartite motif-containing protein 44

1

19

High-throughput

0.457

High

1141263

DX39B
Spliceosome RNA helicase Ddx39b

1

18

High-throughput

0.457

High

812912

TNR4
Tumor necrosis factor receptor superfamily member 4

1

18

Small-scale

0.457

High

1141250

A16L2
Protein Atg16l2

1

11

Small-scale

0.439

High

1141253

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

0

High-throughput

0.438

High

1141256

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.438

High

140168

SNP23
Synaptosomal-associated protein 23

1

3

Small-scale

0.437

High

81952

B7ZNY0
Pde4dip protein

1

20

High-throughput

0.417

High

140150

PEX5
Peroxisomal targeting signal 1 receptor

1

5

High-throughput

0.417

High

1141251

SESD1
SEC14 domain and spectrin repeat-containing protein 1

1

12

High-throughput

0.417

High

1141255

ARFP2
Arfaptin-2

1

3

High-throughput

0.417

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024