Protein: SYKM
Lysine--tRNA ligase, mitochondrial (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)

Gene: SYKM, MSK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: P32048

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0004824 - lysine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

732043

SYKM
Lysine--tRNA ligase, mitochondrial

1

14

Small-scale

0.621

High

149642

RS9A
Small ribosomal subunit protein uS4A

2

2

High-throughput

0.584

High

674475

RS2
Small ribosomal subunit protein uS5

2

2

High-throughput

0.584

High

732057

GBLP
Small ribosomal subunit protein RACK1

2

9

High-throughput

0.584

High

732059

RS20
Small ribosomal subunit protein uS10

2

2

High-throughput

0.584

High

435838

RS13
Small ribosomal subunit protein uS15

2

0

High-throughput

0.559

High

732046

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.536

High

454931

RS19A
Small ribosomal subunit protein eS19A

2

3

High-throughput

0.533

High

689321

RS7A
Small ribosomal subunit protein eS7A

2

2

High-throughput

0.533

High

732050

RSSA1
Small ribosomal subunit protein uS2A

2

5

High-throughput

0.533

High

675794

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.513

High

732044

CDC12
Cell division control protein 12

1

0

High-throughput

0.513

High

656387

KC11
Casein kinase I homolog 1

1

3

High-throughput

0.501

High

656716

KC12
Casein kinase I homolog 2

1

3

High-throughput

0.501

High

732045

IME2
Meiosis induction protein kinase IME2/SME1

1

1

High-throughput

0.501

High

732058

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.501

High

732065

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.493

High

732049

DRS1
ATP-dependent RNA helicase DRS1

1

2

Small-scale

0.481

High

732055

DOA1
Protein DOA1

1

6

Small-scale

0.481

High

732073

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

3

Small-scale

0.481

High

732075

SEN1
Helicase SEN1

1

1

Small-scale

0.481

High

367714

ENO1
Enolase 1

1

4

Small-scale

0.479

High

394032

EFTU
Elongation factor Tu, mitochondrial

1

10

High-throughput

0.479

High

434912

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

688844

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.479

High

732051

SPC29
Spindle pole component 29

1

1

High-throughput

0.479

High

732054

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

732056

YKH1
Uncharacterized oxidoreductase YKL071W

1

2

High-throughput

0.479

High

732061

ATU2
Copper-transporting ATPase

1

2

High-throughput

0.479

High

732071

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

732076

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

732079

CORO
Coronin-like protein

1

4

High-throughput

0.470

High

512037

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

732048

CACP
Carnitine O-acetyltransferase, mitochondrial

1

0

High-throughput

0.458

High

732060

OTU2
OTU domain-containing protein 2

1

0

High-throughput

0.458

High

732062

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

732077

PDR15
ATP-dependent permease PDR15

1

0

High-throughput

0.458

High

523310

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

544109

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

732047

YSC84
Protein YSC84

1

7

Small-scale

0.439

High

732080

ALR1
Magnesium transporter ALR1

1

1

Small-scale

0.439

High

732082

RPN8
26S proteasome regulatory subunit RPN8

1

1

Small-scale

0.439

High

409991

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

433510

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

435535

RS9B
Small ribosomal subunit protein uS4B

1

2

High-throughput

0.437

High

441768

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

455385

RS19B
Small ribosomal subunit protein eS19B

1

3

High-throughput

0.437

High

502636

RS25B
Small ribosomal subunit protein eS25B

1

1

High-throughput

0.437

High

502907

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

512879

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

655413

RS3A2
Small ribosomal subunit protein eS1B

1

4

High-throughput

0.437

High

732052

RS3A1
Small ribosomal subunit protein eS1A

1

4

High-throughput

0.437

High

732063

RS26A
Small ribosomal subunit protein eS26A

1

1

High-throughput

0.437

High

732064

RS26B
Small ribosomal subunit protein eS26B

1

1

High-throughput

0.437

High

732066

RS29A
Small ribosomal subunit protein uS14A

1

1

High-throughput

0.437

High

732067

RS29B
Small ribosomal subunit protein uS14B

1

1

High-throughput

0.437

High

732068

RSSA2
Small ribosomal subunit protein uS2B

1

5

High-throughput

0.437

High

732070

RS7B
Small ribosomal subunit protein eS7B

1

2

High-throughput

0.437

High

732081

ENB1
Siderophore iron transporter ENB1

1

6

High-throughput

0.437

High

732083

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

732085

RS21B
Small ribosomal subunit protein eS21B

1

1

High-throughput

0.437

High

732086

RS25A
Small ribosomal subunit protein eS25A

1

1

High-throughput

0.437

High

150269

RPN13
26S proteasome regulatory subunit RPN13

1

0

Small-scale

0.251

Low

732053

MTH1
Protein MTH1

1

0

Small-scale

0.251

Low

64227

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low

503476

RS28B
Small ribosomal subunit protein eS28B

1

0

High-throughput

0.249

Low

570223

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.249

Low

732069

ILM1
Protein ILM1

1

0

High-throughput

0.249

Low

732072

VHT1
Vitamin H transporter

1

0

High-throughput

0.249

Low

732074

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.249

Low

732078

SEI1
Seipin

1

0

High-throughput

0.249

Low

732084

PSF3
DNA replication complex GINS protein PSF3

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025