Protein: CDC12
Cell division control protein 12 (Septin)

Gene: CDC12
Organism: Saccharomyces cerevisiae S288C
Interactions: 93
UniProt ID: P32468

Gene Ontology (top 5):
GO:0000144 - cellular bud neck septin ring
GO:0000281 - mitotic cytokinesis
GO:0000920 - septum digestion after cytokinesis
GO:0000921 - septin ring assembly
GO:0003924 - GTPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

737072

CDC11
Cell division control protein 11

23

20

Small-scale

0.990

High

736937

CDC3
Cell division control protein 3

18

20

Small-scale

0.988

High

672224

CDC10
Cell division control protein 10

14

20

Small-scale

0.984

High

737344

SHS1
Seventh homolog of septin 1

13

20

Small-scale

0.980

High

737294

CDC12
Cell division control protein 12

8

20

Small-scale

0.955

High

737350

GIN4
Serine/threonine-protein kinase GIN4

5

5

Small-scale

0.720

High

737314

GIC1
GTPase-interacting component 1

4

1

Small-scale

0.689

High

737343

GIC2
GTPase-interacting component 2

4

1

Small-scale

0.689

High

737334

BNI5
Bud neck protein 5

5

0

Small-scale

0.685

High

737330

CLA4
Serine/threonine-protein kinase CLA4

3

1

Small-scale

0.648

High

646343

RAD53
Serine/threonine-protein kinase RAD53

3

1

Small-scale

0.640

High

737323

SPR3
Sporulation-regulated protein 3

1

20

High-throughput

0.621

High

673687

KCC4
Probable serine/threonine-protein kinase KCC4

2

6

Small-scale

0.611

High

392414

HSP82
ATP-dependent molecular chaperone HSP82

2

0

High-throughput

0.593

High

737300

HSL1
Probable serine/threonine-protein kinase HSL1

2

5

Small-scale

0.586

High

737329

BUD4
Bud site selection protein 4

2

1

Small-scale

0.584

High

737342

CYK2
Cytokinesis protein 2

2

2

Small-scale

0.584

High

737306

SHE3
SWI5-dependent HO expression protein 3

2

0

High-throughput

0.565

High

737315

GDS1
GTPase-GDP dissociation stimulator BEM4

2

0

High-throughput

0.565

High

737319

SSB2
Ribosome-associated molecular chaperone SSB2

2

3

High-throughput

0.552

High

737307

RGD1
RHO GTPase-activating protein RGD1

1

4

High-throughput

0.536

High

737311

DOG2
2-deoxyglucose-6-phosphate phosphatase 2

1

1

High-throughput

0.536

High

737328

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

438193

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.515

High

432301

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.513

High

732044

SYKM
Lysine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

737301

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.513

High

737331

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

0

High-throughput

0.513

High

592094

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.500

High

737312

DOG1
2-deoxyglucose-6-phosphate phosphatase 1

1

1

High-throughput

0.489

High

737324

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.486

High

737295

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

1

Small-scale

0.481

High

737299

NIP80
Protein NIP100

1

7

High-throughput

0.481

High

737349

RIO1
Serine/threonine-protein kinase RIO1

1

1

Small-scale

0.481

High

572538

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

590572

HSP26
Heat shock protein 26

1

0

High-throughput

0.479

High

737303

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.479

High

737305

ATG8
Autophagy-related protein 8

1

4

High-throughput

0.479

High

737309

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.479

High

737310

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

737321

NDC80
Kinetochore protein NDC80

1

8

High-throughput

0.464

High

737320

RAD26
DNA repair and recombination protein RAD26

1

0

High-throughput

0.460

High

737325

BUD27
Bud site selection protein 27

1

0

High-throughput

0.460

High

737335

AF9
Protein AF-9 homolog

1

0

High-throughput

0.460

High

737336

NIS1
Protein NIS1

1

0

Small-scale

0.460

High

678079

SYP1
Suppressor of yeast profilin deletion

1

0

Small-scale

0.458

High

709625

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

728696

ACBP
Acyl-CoA-binding protein

1

0

High-throughput

0.458

High

737302

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

737318

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

737340

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

High-throughput

0.458

High

737346

ESA1
Histone acetyltransferase ESA1

1

2

Small-scale

0.457

High

366971

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.457

High

484739

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.457

High

594911

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

1

High-throughput

0.457

High

737352

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.457

High

510304

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.445

High

523359

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

526173

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

544164

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

597072

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.445

High

737347

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.439

High

737351

IQG1
Ras GTPase-activating-like protein IQG1

1

0

Small-scale

0.438

High

670465

SIS1
Protein SIS1

1

5

High-throughput

0.437

High

737316

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.437

High

737317

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.437

High

737326

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.437

High

737332

UBC9
SUMO-conjugating enzyme UBC9

1

6

High-throughput

0.437

High

737337

NUM1
Nuclear migration protein NUM1

1

5

High-throughput

0.437

High

737339

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

670235

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.426

High

737296

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.426

High

737333

BNI4
Protein BNI4

1

0

High-throughput

0.426

High

737308

RCK1
Serine/threonine-protein kinase RCK1

1

1

High-throughput

0.407

High

737298

AFR1
Protein AFR1

4

0

Small-scale

0.358

High

737341

SPC24
Kinetochore protein SPC24

2

0

High-throughput

0.310

High

737322

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

455487

PMM
Phosphomannomutase

1

0

High-throughput

0.279

Low

538331

PYC1
Pyruvate carboxylase 1

1

0

High-throughput

0.279

Low

737313

VMA22
Vacuolar ATPase assembly protein VMA22

1

0

High-throughput

0.279

Low

737338

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.265

Low

367372

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.261

Low

368626

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

555037

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

737327

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

737345

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

594251

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

624726

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.249

Low

706498

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

737297

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

737304

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

737348

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025