Protein: DOA1
Protein DOA1 (Degradation of alpha protein 1) (Ubiquitin fusion degradation protein 3)

Gene: DOA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 59
UniProt ID: P36037

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0010008 - endosome membrane
GO:0010992 - ubiquitin recycling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509490

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

9

16

Small-scale

0.977

High

779960

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

14

High-throughput

0.770

High

679565

CDC48
Cell division control protein 48

14

14

Small-scale

0.766

High

757866

UBX1
UBX domain-containing protein 1

7

5

Small-scale

0.744

High

779946

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

4

3

Small-scale

0.707

High

598395

TUP1
General transcriptional corepressor TUP1

1

18

High-throughput

0.665

High

779956

UFD1
Ubiquitin fusion degradation protein 1

3

1

Small-scale

0.656

High

436377

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

8

Small-scale

0.618

High

632655

DBP4
ATP-dependent RNA helicase HCA4

1

19

Small-scale

0.618

High

701592

UBC8
Ubiquitin-conjugating enzyme E2-24 kDa

1

8

Small-scale

0.618

High

754426

NPL4
Nuclear protein localization protein 4

2

1

Small-scale

0.611

High

402212

RPC1
DNA-directed RNA polymerase III subunit RPC1

2

7

High-throughput

0.588

High

534250

RPA1
DNA-directed RNA polymerase I subunit RPA190

2

7

High-throughput

0.588

High

644906

RPA2
DNA-directed RNA polymerase I subunit RPA135

2

4

High-throughput

0.588

High

779971

PAA1
Polyamine N-acetyltransferase 1

1

0

Small-scale

0.586

High

779952

OTU1
Ubiquitin thioesterase OTU1

1

2

Small-scale

0.573

High

779947

WSS1
DNA-dependent metalloprotease WSS1

1

1

Small-scale

0.561

High

779965

UBX2
UBX domain-containing protein 2

2

0

Small-scale

0.559

High

633542

SAR1
Small COPII coat GTPase SAR1

1

4

Small-scale

0.553

High

754266

DCA13
Protein SOF1

1

16

Small-scale

0.553

High

779970

SMT3
Ubiquitin-like protein SMT3

1

1

Small-scale

0.501

High

665175

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.493

High

732055

SYKM
Lysine--tRNA ligase, mitochondrial

1

6

Small-scale

0.481

High

779954

UBX6
UBX domain-containing protein 6

1

7

Small-scale

0.481

High

452730

ADR1
Regulatory protein ADR1

1

4

Small-scale

0.479

High

459071

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

4

Small-scale

0.479

High

694123

CDC15
Cell division control protein 15

1

16

High-throughput

0.479

High

706767

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

738812

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

Small-scale

0.479

High

745701

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

11

Small-scale

0.479

High

745936

GSP2
GTP-binding nuclear protein GSP2/CNR2

1

10

Small-scale

0.479

High

764187

SPT23
Protein SPT23

1

7

Small-scale

0.479

High

779943

NU170
Nucleoporin NUP170

1

1

High-throughput

0.479

High

779951

VPS27
Vacuolar protein sorting-associated protein 27

1

4

Small-scale

0.479

High

779953

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

7

High-throughput

0.479

High

779955

RL38
Large ribosomal subunit protein eL38

1

4

Small-scale

0.479

High

779957

ARI1
NADPH-dependent aldehyde reductase ARI1

1

2

Small-scale

0.479

High

779964

RPN9
26S proteasome regulatory subunit RPN9

1

5

Small-scale

0.479

High

779966

VMS1
tRNA endonuclease VMS1

1

3

Small-scale

0.479

High

779967

ADH6
NADP-dependent alcohol dehydrogenase 6

1

1

Small-scale

0.479

High

779969

LCB4
Sphingoid long chain base kinase 4

1

1

Small-scale

0.479

High

779972

CEX1
Cytoplasmic export protein 1

1

4

Small-scale

0.479

High

779959

UBX4
UBX domain-containing protein 4

1

0

Small-scale

0.460

High

779950

HUA1
Proline-rich protein HUA1

1

0

Small-scale

0.458

High

779958

DCP2
m7GpppN-mRNA hydrolase

1

0

Small-scale

0.458

High

779961

OSH6
Oxysterol-binding protein homolog 6

1

0

Small-scale

0.458

High

779962

DIG1
Down-regulator of invasive growth 1

1

0

Small-scale

0.458

High

779963

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

526387

HSP72
Heat shock protein SSA2

1

17

High-throughput

0.445

High

544444

SSB1
Ribosome-associated molecular chaperone SSB1

1

17

High-throughput

0.445

High

579192

HSC82
ATP-dependent molecular chaperone HSC82

1

18

High-throughput

0.445

High

726930

HS104
Heat shock protein 104

1

7

High-throughput

0.445

High

752115

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

779949

SSB2
Ribosome-associated molecular chaperone SSB2

1

17

High-throughput

0.445

High

779945

UBX7
UBX domain-containing protein 7

1

12

Small-scale

0.439

High

779948

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

4

Small-scale

0.437

High

613761

MDM10
Mitochondrial distribution and morphology protein 10

1

0

High-throughput

0.249

Low

779944

FZO1
Mitofusin FZO1

1

0

Small-scale

0.249

Low

779968

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025