Protein: PA2GX
Group 10 secretory phospholipase A2 (EC 3.1.1.4) (Group X secretory phospholipase A2) (GX sPLA2) (sPLA2-X) (Phosphatidylcholine 2-acylhydrolase 10)

Gene: PA2GX, PLA2G10
Organism: Homo sapiens
Interactions: 110
UniProt ID: O15496

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001516 - prostaglandin biosynthetic process
GO:0001669 - acrosomal vesicle
GO:0002532 - production of molecular mediator involved in inflammatory response
GO:0003847 - 1-alkyl-2-acetylglycerophosphocholine esterase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

192051

WNT11
Protein Wnt-11

2

1

High-throughput

0.628

High

192057

CO6A1

2

2

High-throughput

0.628

High

192066

WNT5A
Protein Wnt-5a

2

1

High-throughput

0.628

High

192044

FOXH1
Forkhead box protein H1

2

1

High-throughput

0.606

High

192064

HXC8
Homeobox protein Hox-C8

2

1

High-throughput

0.606

High

163015

CHK1
Serine/threonine-protein kinase Chk1

2

0

High-throughput

0.602

High

192052

TPA
Tissue-type plasminogen activator

2

0

High-throughput

0.602

High

192053

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

2

0

High-throughput

0.602

High

192061

FBLN1
Fibulin-1

2

0

High-throughput

0.602

High

192062

GRN
Progranulin

2

0

High-throughput

0.602

High

192070

ALR
FAD-linked sulfhydryl oxidase ALR

2

0

High-throughput

0.602

High

192073

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

0

High-throughput

0.602

High

192119

DC2I1
Cytoplasmic dynein 2 intermediate chain 1

2

0

High-throughput

0.602

High

192121

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

0

High-throughput

0.602

High

192138

EGFL7
Epidermal growth factor-like protein 7

2

0

High-throughput

0.602

High

192142

NEUR3
Sialidase-3

2

0

High-throughput

0.602

High

169329

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

0

High-throughput

0.580

High

192050

TBX6
T-box transcription factor TBX6

2

0

High-throughput

0.580

High

192068

ATX1
Ataxin-1

2

0

High-throughput

0.580

High

192078

ARI5A
AT-rich interactive domain-containing protein 5A

2

0

High-throughput

0.580

High

192127

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

192130

GATA5
Transcription factor GATA-5

2

0

High-throughput

0.580

High

192140

HSF4
Heat shock factor protein 4

2

0

High-throughput

0.580

High

192104

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

2

6

High-throughput

0.574

High

192132

KPCD2
Serine/threonine-protein kinase D2

2

1

High-throughput

0.574

High

192133

TBB1
Tubulin beta-1 chain

2

1

High-throughput

0.574

High

192042

TLX3
T-cell leukemia homeobox protein 3

2

1

High-throughput

0.553

High

192059

MAL
Myelin and lymphocyte protein

2

1

High-throughput

0.553

High

192060

AGT1
Alanine--glyoxylate aminotransferase

2

1

High-throughput

0.553

High

192065

OTX1
Homeobox protein OTX1

2

1

High-throughput

0.553

High

192076

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

2

1

High-throughput

0.553

High

192083

PO4F3
POU domain, class 4, transcription factor 3

2

1

High-throughput

0.553

High

192094

LCE2A
Late cornified envelope protein 2A

2

1

High-throughput

0.553

High

192095

LCE2D
Late cornified envelope protein 2D

2

1

High-throughput

0.553

High

192047

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

1

High-throughput

0.536

High

192058

CO6A2

1

2

High-throughput

0.536

High

192139

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

1

High-throughput

0.536

High

192056

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.513

High

192069

LAMB2
Laminin subunit beta-2

1

0

High-throughput

0.513

High

192072

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.513

High

192074

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.513

High

192081

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.513

High

192141

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

2

High-throughput

0.489

High

192136

PLS4
Phospholipid scramblase 4

1

0

High-throughput

0.460

High

192123

NTAQ1
Protein N-terminal glutamine amidohydrolase

4

0

High-throughput

0.364

High

169827

AURKA
Aurora kinase A

2

0

High-throughput

0.328

High

192046

ATE1
Arginyl-tRNA--protein transferase 1

2

0

High-throughput

0.328

High

192048

TYDP2
Tyrosyl-DNA phosphodiesterase 2

2

0

High-throughput

0.328

High

192080

TARB1
tRNA

2

0

High-throughput

0.328

High

192082

SPIDR
DNA repair-scaffolding protein

2

0

High-throughput

0.328

High

192084

NCOA1
Nuclear receptor coactivator 1

2

0

High-throughput

0.328

High

192085

ZSWM7
Zinc finger SWIM domain-containing protein 7

2

0

High-throughput

0.328

High

192086

LONF2
LON peptidase N-terminal domain and RING finger protein 2

2

0

High-throughput

0.328

High

192088

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

2

0

High-throughput

0.328

High

192098

SWAP1
ATPase SWSAP1

2

0

High-throughput

0.328

High

192107

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

2

0

High-throughput

0.328

High

192108

OAF
Out at first protein homolog

2

0

High-throughput

0.328

High

192110

LRP11
Low-density lipoprotein receptor-related protein 11

2

0

High-throughput

0.328

High

192113

TRM44
Probable tRNA

2

0

High-throughput

0.328

High

192115

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

2

0

High-throughput

0.328

High

192117

ALAT2
Alanine aminotransferase 2

2

0

High-throughput

0.328

High

192126

CK5P1
Mitochondrial tRNA methylthiotransferase CDK5RAP1

2

0

High-throughput

0.328

High

192129

LMF2
Lipase maturation factor 2

2

0

High-throughput

0.328

High

192134

MET17
Ribosome assembly protein METTL17, mitochondrial

2

0

High-throughput

0.328

High

159029

LCE2B
Late cornified envelope protein 2B

2

0

High-throughput

0.320

High

63154

VP37C
Vacuolar protein sorting-associated protein 37C

2

0

High-throughput

0.316

High

70038

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

71091

VGLL3
Transcription cofactor vestigial-like protein 3

2

0

High-throughput

0.316

High

192041

HAIR
Lysine-specific demethylase hairless

2

0

High-throughput

0.316

High

192043

MABP1
Mitogen-activated protein kinase-binding protein 1

2

0

High-throughput

0.316

High

192045

STK16
Serine/threonine-protein kinase 16

2

0

High-throughput

0.316

High

192049

BAG3
BAG family molecular chaperone regulator 3

2

0

High-throughput

0.316

High

192055

RU1C
U1 small nuclear ribonucleoprotein C

2

0

High-throughput

0.316

High

192063

AQP1
Aquaporin-1

2

0

High-throughput

0.316

High

192075

PITX1
Pituitary homeobox 1

2

0

High-throughput

0.316

High

192077

CREB5
Cyclic AMP-responsive element-binding protein 5

2

0

High-throughput

0.316

High

192079

INCA1
Protein INCA1

2

0

High-throughput

0.316

High

192089

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

192090

LCE1C
Late cornified envelope protein 1C

2

0

High-throughput

0.316

High

192092

LCE1A
Late cornified envelope protein 1A

2

0

High-throughput

0.316

High

192099

CA094
Uncharacterized protein C1orf94

2

0

High-throughput

0.316

High

192101

KR261
Keratin-associated protein 26-1

2

0

High-throughput

0.316

High

192105

SAXO4
Stabilizer of axonemal microtubules 4

2

0

High-throughput

0.316

High

192109

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.316

High

192112

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

192114

CTSR1
Cation channel sperm-associated protein 1

2

0

High-throughput

0.316

High

192118

F222B
Protein FAM222B

2

0

High-throughput

0.316

High

192120

TFG
Protein TFG

2

0

High-throughput

0.316

High

192124

CC120
Coiled-coil domain-containing protein 120

2

0

High-throughput

0.316

High

192125

ZC3HA
Zinc finger CCCH domain-containing protein 10

2

0

High-throughput

0.316

High

192131

BEX2
Protein BEX2

2

0

High-throughput

0.316

High

192143

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

2

0

High-throughput

0.316

High

192054

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.279

Low

192097

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

192100

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

0

High-throughput

0.279

Low

192102

FIGL1
Fidgetin-like protein 1

1

0

High-throughput

0.279

Low

192103

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

0

High-throughput

0.279

Low

192111

ERO1B
ERO1-like protein beta

1

0

High-throughput

0.279

Low

192116

ZN507
Zinc finger protein 507

1

0

High-throughput

0.279

Low

192122

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.279

Low

192128

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.279

Low

192137

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

0

High-throughput

0.279

Low

192106

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

192067

HXA1
Homeobox protein Hox-A1

1

0

High-throughput

0.251

Low

192071

KR108
Keratin-associated protein 10-8

1

0

High-throughput

0.251

Low

192087

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

192091

LCE1F
Late cornified envelope protein 1F

1

0

High-throughput

0.251

Low

192093

LCE3A
Late cornified envelope protein 3A

1

0

High-throughput

0.251

Low

192096

LCE5A
Late cornified envelope protein 5A

1

0

High-throughput

0.251

Low

192135

MYO10
Unconventional myosin-X

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025