Protein: CENPH
Centromere protein H (CENP-H) (Interphase centromere complex protein 35)

Gene: CENPH
Organism: Homo sapiens
Interactions: 122
UniProt ID: Q9H3R5

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000939 - inner kinetochore
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1412121

CENPK
Centromere protein K

8

1

Small-scale

0.971

High

1432860

CENPM
Centromere protein M

4

1

High-throughput

0.900

High

1366698

CENPI
Centromere protein I

4

1

Small-scale

0.892

High

164090

NDC80
Kinetochore protein NDC80 homolog

6

1

Small-scale

0.731

High

1259025

CENPU
Centromere protein U

7

0

Small-scale

0.715

High

1432864

TEKT2
Tektin-2

4

0

High-throughput

0.670

High

1234742

CENPP
Centromere protein P

3

1

Small-scale

0.650

High

1392635

CENPN
Centromere protein N

3

1

Small-scale

0.650

High

280955

HYPM
Huntingtin-interacting protein M

3

0

High-throughput

0.636

High

1271996

CENPQ
Centromere protein Q

3

0

High-throughput

0.634

High

1110721

DCTN2
Dynactin subunit 2

3

0

High-throughput

0.625

High

1401164

SPAG5
Sperm-associated antigen 5

3

0

High-throughput

0.620

High

1432856

CENPH
Centromere protein H

2

0

Small-scale

0.613

High

1413955

CENPO
Centromere protein O

2

1

Small-scale

0.611

High

634631

LMNB1
Lamin-B1

2

1

High-throughput

0.606

High

50934

SYCE3
Synaptonemal complex central element protein 3

2

0

High-throughput

0.602

High

184073

ACOX3
Peroxisomal acyl-coenzyme A oxidase 3

2

0

High-throughput

0.602

High

1430810

ING2
Inhibitor of growth protein 2

2

0

High-throughput

0.602

High

128064

PSD11
26S proteasome non-ATPase regulatory subunit 11

2

2

High-throughput

0.601

High

1322167

CENPL
Centromere protein L

2

1

High-throughput

0.601

High

1015306

ERH
Enhancer of rudimentary homolog

2

0

High-throughput

0.580

High

1253689

ZN493
Zinc finger protein 493

2

0

High-throughput

0.580

High

1432862

ABI2
Abl interactor 2

2

0

High-throughput

0.580

High

1103031

CENPR
Centromere protein R

2

0

High-throughput

0.576

High

1110819

PKD2
Polycystin-2

2

0

High-throughput

0.576

High

1385065

CENPT
Centromere protein T

1

1

High-throughput

0.575

High

1095226

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

0

High-throughput

0.549

High

883685

CENPA
Histone H3-like centromeric protein A

2

0

Small-scale

0.547

High

507367

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

1

High-throughput

0.536

High

1432859

TRI36
E3 ubiquitin-protein ligase TRIM36

1

0

Small-scale

0.529

High

270050

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.513

High

300838

KRT38
Keratin, type I cuticular Ha8

1

0

High-throughput

0.513

High

686424

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

848718

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

859997

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

1048276

HGFA
Hepatocyte growth factor activator serine protease

1

0

High-throughput

0.513

High

1248469

PARM1
Prostate androgen-regulated mucin-like protein 1

1

0

High-throughput

0.513

High

1277635

K1C27
Keratin, type I cytoskeletal 27

1

0

High-throughput

0.513

High

1324862

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1361761

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

1429743

ADT4
ADP/ATP translocase 4

1

0

High-throughput

0.513

High

1432865

GGA1
ADP-ribosylation factor-binding protein GGA1

1

0

High-throughput

0.513

High

508616

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

1143018

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.493

High

213430

ZSC12
Zinc finger and SCAN domain-containing protein 12

1

0

High-throughput

0.493

High

374927

RASH
GTPase HRas

1

0

High-throughput

0.493

High

702502

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

958192

ARP3
Actin-related protein 3

1

0

High-throughput

0.493

High

1397804

ODAD1
Outer dynein arm-docking complex subunit 1

1

1

High-throughput

0.489

High

1419592

NUF2
Kinetochore protein Nuf2

1

1

Small-scale

0.481

High

384546

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.480

High

1406259

KIF2C
Kinesin-like protein KIF2C

1

0

Small-scale

0.480

High

1159540

NTRK2
BDNF/NT-3 growth factors receptor

1

2

High-throughput

0.479

High

1227451

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

650413

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.470

High

1280787

Q7Z758
C8orf58 protein

1

1

High-throughput

0.470

High

260447

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

278962

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

414616

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

589670

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

810373

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

928225

HAP1
Huntingtin-associated protein 1

1

0

High-throughput

0.458

High

935125

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

942881

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

967556

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

1324636

CENPS
Centromere protein S

1

0

Small-scale

0.458

High

1334172

POC1A
POC1 centriolar protein homolog A

1

0

High-throughput

0.458

High

1399093

SCLT1
Sodium channel and clathrin linker 1

1

0

High-throughput

0.458

High

1406489

ATX2
Ataxin-2

1

0

High-throughput

0.458

High

1432858

CPAP
Centrosomal P4.1-associated protein

1

0

High-throughput

0.458

High

1432869

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.458

High

1432870

SGT1
Protein SGT1 homolog

1

0

Small-scale

0.458

High

128320

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

1

High-throughput

0.445

High

1136598

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

1

High-throughput

0.445

High

1332867

CH058
Uncharacterized protein C8orf58

1

1

High-throughput

0.439

High

412604

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

244496

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

0

High-throughput

0.426

High

255481

SNX2
Sorting nexin-2

1

0

High-throughput

0.426

High

448065

ITAV
Integrin alpha-V

1

0

High-throughput

0.426

High

638138

AOFA
Amine oxidase [flavin-containing] A

1

0

High-throughput

0.426

High

1041854

CENPC
Centromere protein C

1

0

High-throughput

0.426

High

1149711

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.426

High

1316988

FAM9B
Protein FAM9B

1

0

High-throughput

0.426

High

1431396

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

High-throughput

0.426

High

1432857

FA83D
Protein FAM83D

1

0

High-throughput

0.426

High

1432863

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

0

High-throughput

0.426

High

1432867

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

0

High-throughput

0.426

High

1039116

RASF7
Ras association domain-containing protein 7

4

0

High-throughput

0.360

High

1090009

LMAN2
Vesicular integral-membrane protein VIP36

4

0

High-throughput

0.360

High

1194667

CCD40
Coiled-coil domain-containing protein 40

3

0

High-throughput

0.352

High

63317

ODAD3
Outer dynein arm-docking complex subunit 3

3

0

High-throughput

0.347

High

1432861

IFT57
Intraflagellar transport protein 57 homolog

3

0

High-throughput

0.347

High

1219935

BSPRY
B box and SPRY domain-containing protein

2

0

High-throughput

0.328

High

1357797

CC107
Coiled-coil domain-containing protein 107

2

0

High-throughput

0.328

High

1313696

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.318

High

1131229

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

1276158

NUP54
Nucleoporin p54

2

0

High-throughput

0.316

High

1314914

CC146
Coiled-coil domain-containing protein 146

2

0

High-throughput

0.316

High

1346700

CA216
UPF0500 protein C1orf216

2

0

High-throughput

0.316

High

1432051

RASF4
Ras association domain-containing protein 4

2

0

High-throughput

0.316

High

1022472

IDD
Integral membrane protein DGCR2/IDD

2

0

High-throughput

0.313

High

1198280

FND3B
Fibronectin type III domain-containing protein 3B

2

0

High-throughput

0.313

High

212488

SPIT2
Kunitz-type protease inhibitor 2

1

0

High-throughput

0.279

Low

295878

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.279

Low

914343

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

932133

EPHA4
Ephrin type-A receptor 4

1

0

High-throughput

0.279

Low

1179855

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1254081

LRC55
Leucine-rich repeat-containing protein 55

1

0

High-throughput

0.279

Low

1352518

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.279

Low

1410525

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

1429450

DRC3
Dynein regulatory complex subunit 3

1

0

High-throughput

0.279

Low

1330394

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

1432866

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

219367

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.232

Low

296377

ATRN
Attractin

1

0

High-throughput

0.232

Low

388667

C1QA
Complement C1q subcomponent subunit A

1

0

High-throughput

0.232

Low

683654

ITB8
Integrin beta-8

1

0

High-throughput

0.232

Low

1180319

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.232

Low

1335850

DYHC2
Cytoplasmic dynein 2 heavy chain 1

1

0

High-throughput

0.232

Low

1432868

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.232

Low

1432871

C170B
Centrosomal protein of 170 kDa protein B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025