Protein: RPP25
Ribonuclease P protein subunit p25 (RNase P protein subunit p25)

Gene: RPP25
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q9BUL9

Gene Ontology (top 5):
GO:0000172 - ribonuclease MRP complex
GO:0001682 - tRNA 5'-leader removal
GO:0003723 - RNA binding
GO:0004526 - ribonuclease P activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

294948

POP7
Ribonuclease P protein subunit p20

6

1

Small-scale

0.950

High

342460

RPP29
Ribonuclease P protein subunit p29

4

1

Small-scale

0.700

High

1380318

POP5
Ribonuclease P/MRP protein subunit POP5

4

2

Small-scale

0.700

High

1405369

POP1
Ribonucleases P/MRP protein subunit POP1

4

1

Small-scale

0.700

High

325448

RPP14
Ribonuclease P protein subunit p14

4

1

Small-scale

0.694

High

294996

RPP40
Ribonuclease P protein subunit p40

3

1

High-throughput

0.667

High

447379

NPM
Nucleophosmin

3

3

High-throughput

0.667

High

1005765

RPP38
Ribonuclease P protein subunit p38

3

1

High-throughput

0.667

High

1005824

RPP30
Ribonuclease P protein subunit p30

3

1

High-throughput

0.667

High

1239143

NEPRO
Nucleolus and neural progenitor protein

3

1

High-throughput

0.667

High

1409822

RBM4B
RNA-binding protein 4B

3

3

High-throughput

0.667

High

1414416

RPP21
Ribonuclease P protein subunit p21

3

1

Small-scale

0.662

High

1371371

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

3

0

High-throughput

0.638

High

1414413

RBM4
RNA-binding protein 4

2

3

High-throughput

0.628

High

1181341

CR021
UPF0711 protein C18orf21

3

1

High-throughput

0.609

High

1336455

PNMA1
Paraneoplastic antigen Ma1

2

1

High-throughput

0.606

High

1414414

BACH2
Transcription regulator protein BACH2

2

2

High-throughput

0.606

High

1414421

RBL2A
Rab-like protein 2A

3

1

High-throughput

0.599

High

343799

LDOC1
Protein LDOC1

2

0

High-throughput

0.580

High

1148553

SF3B4
Splicing factor 3B subunit 4

2

0

High-throughput

0.580

High

1278735

ZN438
Zinc finger protein 438

2

0

High-throughput

0.580

High

1332025

BANP
Protein BANP

2

0

High-throughput

0.580

High

1372062

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.580

High

1414417

PDLI7
PDZ and LIM domain protein 7

2

0

High-throughput

0.580

High

1414419

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.549

High

288752

NPM3
Nucleoplasmin-3

1

3

High-throughput

0.536

High

1016590

SRSF3
Serine/arginine-rich splicing factor 3

1

5

High-throughput

0.536

High

1130830

RRP5
Protein RRP5 homolog

1

1

High-throughput

0.536

High

1414422

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

1386558

OPTN
Optineurin

1

1

High-throughput

0.515

High

226994

ENSA
Alpha-endosulfine

1

0

High-throughput

0.513

High

1117653

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.513

High

1366547

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.513

High

1411876

TCAL7
Transcription elongation factor A protein-like 7

1

0

High-throughput

0.513

High

1414415

PIP30
PSME3-interacting protein

1

0

High-throughput

0.513

High

274733

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.493

High

361347

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

775289

FUS
RNA-binding protein FUS

1

0

High-throughput

0.493

High

1025139

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.493

High

1031945

NC2B
Protein Dr1

1

0

High-throughput

0.493

High

1209599

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.493

High

1414423

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.493

High

1199675

KLH22
Kelch-like protein 22

1

1

High-throughput

0.489

High

373025

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

406582

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

1194345

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

1393649

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1258382

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.470

High

1311774

HOMEZ
Homeobox and leucine zipper protein Homez

1

0

High-throughput

0.460

High

1271832

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

354279

MOC2B
Molybdopterin synthase catalytic subunit

1

0

High-throughput

0.426

High

85425

B7ZBD5
RAB, member of RAS oncogene family like 2A

1

1

High-throughput

0.407

High

640615

MK
Midkine

2

0

High-throughput

0.328

High

618100

K1C15
Keratin, type I cytoskeletal 15

2

0

High-throughput

0.316

High

639640

SAT1
Diamine acetyltransferase 1

2

0

High-throughput

0.316

High

1206677

LRC73
Leucine-rich repeat-containing protein 73

2

0

High-throughput

0.316

High

1356069

DDI1
Protein DDI1 homolog 1

2

0

High-throughput

0.316

High

1414418

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1414420

ABI2
Abl interactor 2

2

0

High-throughput

0.316

High

488079

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

320026

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

355642

MOC2A
Molybdopterin synthase sulfur carrier subunit

1

0

High-throughput

0.249

Low

1340193

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025