Protein: NEPRO
Nucleolus and neural progenitor protein

Gene: NEPRO
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q6NW34

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0045665 - negative regulation of neuron differentiation
GO:0045747 - positive regulation of Notch signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

447116

NPM
Nucleophosmin

6

1

High-throughput

0.732

High

288676

NPM3
Nucleoplasmin-3

4

1

High-throughput

0.697

High

1239143

RPP25
Ribonuclease P protein subunit p25

3

1

High-throughput

0.667

High

342442

RPP29
Ribonuclease P protein subunit p29

4

0

Small-scale

0.664

High

1005799

RPP30
Ribonuclease P protein subunit p30

4

0

Small-scale

0.664

High

1239124

RP25L
Ribonuclease P protein subunit p25-like protein

3

1

High-throughput

0.650

High

208286

RRP8
Ribosomal RNA-processing protein 8

2

0

High-throughput

0.602

High

904840

MECP2
Methyl-CpG-binding protein 2

2

0

High-throughput

0.602

High

1239139

ZN512
Zinc finger protein 512

2

0

High-throughput

0.602

High

1239147

NXF2
Nuclear RNA export factor 2

2

0

High-throughput

0.602

High

294933

POP7
Ribonuclease P protein subunit p20

2

0

High-throughput

0.585

High

294983

RPP40
Ribonuclease P protein subunit p40

2

0

Small-scale

0.585

High

325436

RPP14
Ribonuclease P protein subunit p14

2

0

Small-scale

0.585

High

979007

RS6
Small ribosomal subunit protein eS6

2

0

High-throughput

0.585

High

1005742

RPP38
Ribonuclease P protein subunit p38

2

0

High-throughput

0.585

High

1239142

POP1
Ribonucleases P/MRP protein subunit POP1

2

0

High-throughput

0.585

High

96699

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.584

High

396327

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

464989

SP1
Transcription factor Sp1

1

0

High-throughput

0.537

High

191678

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.513

High

338872

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.513

High

428817

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

658237

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.513

High

785232

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

859323

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

969919

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

978573

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

1013072

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

1027528

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.513

High

1057777

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.513

High

1130759

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.513

High

1137072

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

0

High-throughput

0.513

High

1239122

ZN467
Zinc finger protein 467

1

0

High-throughput

0.513

High

1239129

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

1239132

POP5
Ribonuclease P/MRP protein subunit POP5

1

0

High-throughput

0.513

High

1239138

ZN668
Zinc finger protein 668

1

0

High-throughput

0.513

High

1239148

SENP3
Sentrin-specific protease 3

1

0

High-throughput

0.513

High

936192

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

High-throughput

0.493

High

596169

H12
Histone H1.2

1

1

High-throughput

0.479

High

1239130

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1239136

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

1

High-throughput

0.479

High

1239150

WDR55
WD repeat-containing protein 55

1

2

High-throughput

0.479

High

129181

MEN1
Menin

1

0

High-throughput

0.458

High

132102

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

187106

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.458

High

190958

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

194237

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

242012

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

372310

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

487435

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

588936

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

686216

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.458

High

695723

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

810166

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

877523

LHX1
LIM/homeobox protein Lhx1

1

0

High-throughput

0.458

High

934746

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

936778

NP1L1
Nucleosome assembly protein 1-like 1

1

0

High-throughput

0.458

High

937786

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

982706

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

994606

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

1004712

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1089716

ILF3
Interleukin enhancer-binding factor 3

1

0

High-throughput

0.458

High

1239120

NEPRO
Nucleolus and neural progenitor protein

1

0

High-throughput

0.458

High

1239121

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

1239127

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1239135

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

High-throughput

0.458

High

1239137

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1239144

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1239145

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.458

High

1239146

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1239152

NLE1
Notchless protein homolog 1

1

0

High-throughput

0.458

High

1239153

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1239155

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

High-throughput

0.458

High

1239156

SCML1
Sex comb on midleg-like protein 1

1

0

High-throughput

0.458

High

1239159

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1037212

H11
Histone H1.1

1

1

High-throughput

0.445

High

1212335

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

420576

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.437

High

598112

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

1

High-throughput

0.437

High

1239126

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.437

High

1239154

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

601730

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.426

High

1239151

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.426

High

69952

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

1037527

RL18A
Large ribosomal subunit protein eL20

2

0

High-throughput

0.328

High

1181314

CR021
UPF0711 protein C18orf21

2

0

High-throughput

0.328

High

422342

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.279

Low

657256

KALM
Anosmin-1

1

0

High-throughput

0.279

Low

884120

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.279

Low

1126435

CAPR1
Caprin-1

1

0

High-throughput

0.279

Low

1127406

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1239125

KKCC1
Calcium/calmodulin-dependent protein kinase kinase 1

1

0

High-throughput

0.279

Low

1239131

TFG
Protein TFG

1

0

High-throughput

0.279

Low

1239140

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

1239141

TMM74
Transmembrane protein 74

1

0

High-throughput

0.279

Low

1239157

G3BP2
Ras GTPase-activating protein-binding protein 2

1

0

High-throughput

0.279

Low

1239158

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.279

Low

1239160

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

0

High-throughput

0.279

Low

428426

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.249

Low

451007

LDHB
L-lactate dehydrogenase B chain

1

0

High-throughput

0.249

Low

858959

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.249

Low

859873

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.249

Low

894823

EMD
Emerin

1

0

High-throughput

0.249

Low

984818

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.249

Low

1239128

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

1239133

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

1239149

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1239123

LRRT3
Leucine-rich repeat transmembrane neuronal protein 3

1

0

High-throughput

0.232

Low

1239134

CC049
Putative uncharacterized protein C3orf49

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025