Protein: IFI6
Interferon alpha-inducible protein 6 (Interferon-induced protein 6-16) (Ifi-6-16)

Gene: IFI6
Organism: Homo sapiens
Interactions: 54
UniProt ID: P09912

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005743 - mitochondrial inner membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

488047

STAT2
Signal transducer and activator of transcription 2

4

1

Small-scale

0.676

High

488044

STAT1
Signal transducer and activator of transcription 1-alpha/beta

3

1

Small-scale

0.640

High

488041

IRF1
Interferon regulatory factor 1

2

1

Small-scale

0.584

High

488049

IRF9
Interferon regulatory factor 9

2

1

Small-scale

0.584

High

488045

PRC2A
Protein PRRC2A

1

1

High-throughput

0.536

High

488072

CBP
CREB-binding protein

2

1

Small-scale

0.533

High

212536

GPAA1
GPI-anchor transamidase component GPAA1

1

0

High-throughput

0.513

High

488068

CATIN
Splicing factor Cactin

1

0

High-throughput

0.513

High

488081

PIGU
GPI-anchor transamidase component PIGU

1

0

High-throughput

0.513

High

488083

TM39A
Transmembrane protein 39A

1

0

High-throughput

0.513

High

488084

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.513

High

488085

SLTM
SAFB-like transcription modulator

1

0

High-throughput

0.513

High

488088

ZO2
Tight junction protein 2

1

0

High-throughput

0.513

High

488043

H2AX
Histone H2AX

1

1

High-throughput

0.489

High

488053

H2A2C
Histone H2A type 2-C

1

1

High-throughput

0.489

High

488058

UBN2
Ubinuclein-2

1

1

High-throughput

0.489

High

488070

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

1

High-throughput

0.489

High

488078

DIDO1
Death-inducer obliterator 1

1

2

High-throughput

0.489

High

488091

CABIN
Calcineurin-binding protein cabin-1

1

1

High-throughput

0.489

High

421365

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

488042

BIP
Endoplasmic reticulum chaperone BiP

1

0

Small-scale

0.458

High

488071

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

280471

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.279

Low

488046

RBM25
RNA-binding protein 25

1

0

High-throughput

0.279

Low

488050

SFSWA
Splicing factor, suppressor of white-apricot homolog

1

0

High-throughput

0.279

Low

488051

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

0

High-throughput

0.279

Low

488052

BRD3
Bromodomain-containing protein 3

1

0

High-throughput

0.279

Low

488054

KNOP1
Lysine-rich nucleolar protein 1

1

0

High-throughput

0.279

Low

488055

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

High-throughput

0.279

Low

488056

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

0

High-throughput

0.279

Low

488057

PR38B
Pre-mRNA-splicing factor 38B

1

0

High-throughput

0.279

Low

488059

NKAP1
Uncharacterized protein NKAPD1

1

0

High-throughput

0.279

Low

488060

DDX46
Probable ATP-dependent RNA helicase DDX46

1

0

High-throughput

0.279

Low

488061

RSRC2
Arginine/serine-rich coiled-coil protein 2

1

0

High-throughput

0.279

Low

488062

VRK3
Serine/threonine-protein kinase VRK3

1

0

High-throughput

0.279

Low

488063

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.279

Low

488064

LEMD2
LEM domain-containing protein 2

1

0

High-throughput

0.279

Low

488065

PPHLN
Periphilin-1

1

0

High-throughput

0.279

Low

488066

RP9
Retinitis pigmentosa 9 protein

1

0

High-throughput

0.279

Low

488067

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.279

Low

488069

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.279

Low

488073

RMXL1
RNA binding motif protein, X-linked-like-1

1

0

High-throughput

0.279

Low

488074

RRP36
Ribosomal RNA processing protein 36 homolog

1

0

High-throughput

0.279

Low

488075

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.279

Low

488076

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.279

Low

488077

SCAFB
Protein SCAF11

1

0

High-throughput

0.279

Low

488079

RPP25
Ribonuclease P protein subunit p25

1

0

High-throughput

0.279

Low

488080

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.279

Low

488082

ESF1
ESF1 homolog

1

0

High-throughput

0.279

Low

488086

CWC25
Pre-mRNA-splicing factor CWC25 homolog

1

0

High-throughput

0.279

Low

488087

CDK12
Cyclin-dependent kinase 12

1

0

High-throughput

0.279

Low

488089

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

0

High-throughput

0.279

Low

488090

WBP11
WW domain-binding protein 11

1

0

High-throughput

0.279

Low

488048

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025