Protein: TF2H3
General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit)

Gene: TF2H3, GTF2H3
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q13889

Gene Ontology (top 5):
GO:0000438 - core TFIIH complex portion of holo TFIIH complex
GO:0000439 - transcription factor TFIIH core complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1118806

TF2H2
General transcription factor IIH subunit 2

9

3

Small-scale

0.975

High

1118847

TF2H4
General transcription factor IIH subunit 4

5

2

Small-scale

0.931

High

1118841

T2H2L
General transcription factor IIH subunit 2-like protein

5

3

High-throughput

0.931

High

622807

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

10

1

Small-scale

0.754

High

897267

CDK7
Cyclin-dependent kinase 7

9

1

Small-scale

0.753

High

744660

TF2H1
General transcription factor IIH subunit 1

7

1

Small-scale

0.753

High

1118842

TF2H5
General transcription factor IIH subunit 5

5

1

Small-scale

0.720

High

611668

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

2

2

Small-scale

0.595

High

396080

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

520029

ANDR
Androgen receptor

1

2

Small-scale

0.561

High

695419

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

High-throughput

0.559

High

770386

T2FA
General transcription factor IIF subunit 1

1

1

High-throughput

0.536

High

1118848

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.515

High

132475

CDC7
Cell division cycle 7-related protein kinase

1

0

High-throughput

0.513

High

704745

ERCC5
DNA excision repair protein ERCC-5

1

0

High-throughput

0.513

High

729555

CASPE
Caspase-14

1

0

High-throughput

0.513

High

832899

CETN2
Centrin-2

1

0

High-throughput

0.513

High

1118846

ZN784
Zinc finger protein 784

1

0

High-throughput

0.513

High

1118851

PRD11
PR domain-containing protein 11

1

0

High-throughput

0.513

High

507951

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

708897

T2EA
General transcription factor IIE subunit 1

1

1

Small-scale

0.501

High

334006

SMC2
Structural maintenance of chromosomes protein 2

1

0

High-throughput

0.493

High

601662

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.493

High

926465

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

936182

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

High-throughput

0.493

High

1118853

TR150
Thyroid hormone receptor-associated protein 3

1

0

High-throughput

0.493

High

404046

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

889419

CLK1
Dual specificity protein kinase CLK1

1

2

High-throughput

0.479

High

889566

CLK2
Dual specificity protein kinase CLK2

1

2

High-throughput

0.479

High

889728

CLK3
Dual specificity protein kinase CLK3

1

2

High-throughput

0.479

High

302517

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

High-throughput

0.458

High

588659

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

768150

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

938097

ANM2
Protein arginine N-methyltransferase 2

1

0

High-throughput

0.458

High

988353

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.458

High

1088832

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1105274

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.458

High

1118838

BRD3
Bromodomain-containing protein 3

1

0

High-throughput

0.458

High

1118844

SHLD2
Shieldin complex subunit 2

1

0

High-throughput

0.458

High

1118845

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1118852

XPO7
Exportin-7

1

0

High-throughput

0.458

High

908746

MAT1
CDK-activating kinase assembly factor MAT1

1

1

High-throughput

0.445

High

1118840

CHCH9
Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial

1

0

High-throughput

0.426

High

1118843

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.426

High

1118849

EAF1
ELL-associated factor 1

1

0

High-throughput

0.426

High

1064986

FGL1
Fibrinogen-like protein 1

2

0

High-throughput

0.298

High

271597

ICOSL
ICOS ligand

1

0

High-throughput

0.279

Low

989733

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

0

High-throughput

0.279

Low

345791

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

1118839

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1118850

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025