Protein: HIRP3
HIRA-interacting protein 3

Gene: HIRP3, HIRIP3
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q9BW71

Gene Ontology (top 5):
GO:0000511 - H2A-H2B histone complex chaperone activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006325 - chromatin organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

981064

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.754

High

997988

CSK21
Casein kinase II subunit alpha

8

3

Small-scale

0.754

High

625595

CSK22
Casein kinase II subunit alpha'

8

3

High-throughput

0.752

High

591825

H2AX
Histone H2AX

1

6

High-throughput

0.691

High

995239

CSK2B
Casein kinase II subunit beta

5

0

Small-scale

0.687

High

943419

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.665

High

1372291

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.665

High

419184

H2A1B
Histone H2A type 1-B/E

1

6

High-throughput

0.618

High

883676

CENPA
Histone H3-like centromeric protein A

1

9

High-throughput

0.618

High

1017179

H33
Histone H3.3

1

9

High-throughput

0.618

High

1415947

SGK2
Serine/threonine-protein kinase Sgk2

2

0

High-throughput

0.580

High

1415951

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

2

0

High-throughput

0.576

High

1337834

CSK23
Casein kinase II subunit alpha 3

2

3

High-throughput

0.571

High

1006672

SRPK2
SRSF protein kinase 2

1

8

High-throughput

0.550

High

1402556

SRPK1
SRSF protein kinase 1

1

8

High-throughput

0.550

High

769774

RFC4
Replication factor C subunit 4

1

1

High-throughput

0.536

High

888302

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.536

High

1065407

SSRP1
FACT complex subunit SSRP1

1

4

High-throughput

0.536

High

1415950

ASF1B
Histone chaperone ASF1B

1

1

High-throughput

0.536

High

521908

H14
Histone H1.4

1

6

High-throughput

0.515

High

717590

PDIA3
Protein disulfide-isomerase A3

1

1

High-throughput

0.515

High

1415956

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

1

High-throughput

0.515

High

843938

HD
Huntingtin

1

1

High-throughput

0.515

High

557448

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.513

High

813490

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

0

High-throughput

0.513

High

837820

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.513

High

1307390

RIOX2
Ribosomal oxygenase 2

1

0

High-throughput

0.513

High

926684

HIRA
Protein HIRA

1

3

Small-scale

0.501

High

387143

TNNC2
Troponin C, skeletal muscle

1

1

High-throughput

0.489

High

1091035

BFSP1
Filensin

1

2

High-throughput

0.489

High

1349831

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

High-throughput

0.489

High

141083

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

242792

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

636141

CD11B
Cyclin-dependent kinase 11B

1

3

High-throughput

0.479

High

855511

ATRX
Transcriptional regulator ATRX

1

2

High-throughput

0.479

High

886317

ARL4D
ADP-ribosylation factor-like protein 4D

1

4

High-throughput

0.479

High

889494

CLK1
Dual specificity protein kinase CLK1

1

4

High-throughput

0.479

High

889649

CLK2
Dual specificity protein kinase CLK2

1

4

High-throughput

0.479

High

889804

CLK3
Dual specificity protein kinase CLK3

1

4

High-throughput

0.479

High

897961

CDK9
Cyclin-dependent kinase 9

1

4

High-throughput

0.479

High

971019

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

980261

H4
Histone H4

1

3

High-throughput

0.479

High

1415953

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1415955

CD11A
Cyclin-dependent kinase 11A

1

3

High-throughput

0.479

High

173305

XPO1
Exportin-1

1

0

High-throughput

0.458

High

1415948

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1415952

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

1415959

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

423061

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.457

High

622849

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

2

High-throughput

0.445

High

788331

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

1

High-throughput

0.445

High

1347150

WDR48
WD repeat-containing protein 48

1

2

High-throughput

0.445

High

1349268

WDR20
WD repeat-containing protein 20

1

1

High-throughput

0.445

High

942856

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.437

High

1255360

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

573884

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.426

High

1179191

CTC1
CST complex subunit CTC1

1

0

High-throughput

0.426

High

1326070

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

1415954

SHOC2
Leucine-rich repeat protein SHOC-2

1

0

High-throughput

0.426

High

451635

GPX1
Glutathione peroxidase 1

1

1

High-throughput

0.407

High

1030331

AMPD2
AMP deaminase 2

3

0

High-throughput

0.342

High

505197

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

884221

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.279

Low

1140139

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.279

Low

1415957

COF2
Cofilin-2

1

0

High-throughput

0.279

Low

1415958

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.279

Low

608345

EGLN
Endoglin

1

0

High-throughput

0.261

Low

540080

BCR
Breakpoint cluster region protein

1

0

High-throughput

0.249

Low

1415949

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.238

Low

1240799

T2H2L
General transcription factor IIH subunit 2-like protein

1

0

High-throughput

0.232

Low

1322874

PURA1
Adenylosuccinate synthetase isozyme 1

1

0

High-throughput

0.232

Low

1415030

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025