Protein: IRA1
Inhibitory regulator protein IRA1

Gene: IRA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 29
UniProt ID: P18963

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005739 - mitochondrion
GO:0007193 - adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0016020 - membrane
GO:0046580 - negative regulation of Ras protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376210

RAS2
Ras-like protein 2

2

20

Small-scale

0.799

High

617969

IRA2
Inhibitory regulator protein IRA2

2

14

Small-scale

0.754

High

617968

IRA1
Inhibitory regulator protein IRA1

1

13

High-throughput

0.590

High

617981

GPB2
Guanine nucleotide-binding protein subunit beta 2

2

3

Small-scale

0.584

High

617988

GPB1
Guanine nucleotide-binding protein subunit beta 1

2

3

Small-scale

0.584

High

416857

CDC25
Cell division control protein 25

1

2

High-throughput

0.494

High

617973

HRR25
Casein kinase I homolog HRR25

1

12

High-throughput

0.489

High

617978

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

10

High-throughput

0.489

High

617990

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

617982

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

617989

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

392194

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.437

High

523000

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.437

High

617970

TRX2
Thioredoxin-2

1

1

High-throughput

0.437

High

617971

PRR1
Serine/threonine-protein kinase PRR1

1

1

High-throughput

0.437

High

617972

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

617974

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

6

High-throughput

0.437

High

617976

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.437

High

617977

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

617984

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

7

High-throughput

0.437

High

617985

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

617987

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

617986

SML1
Ribonucleotide reductase inhibitor protein SML1

1

0

High-throughput

0.269

Low

94531

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.251

Low

617980

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

617975

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.232

Low

617979

RIX1
Pre-rRNA-processing protein RIX1

1

0

High-throughput

0.232

Low

617983

LTO1
Protein LTO1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025