Protein: RIX1
Pre-rRNA-processing protein RIX1 (Involved in processing IST2 protein 2) (Ribosomal export protein 1)

Gene: RIX1
Organism: Saccharomyces cerevisiae S288C
Interactions: 168
UniProt ID: P38883

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

806639

IPI3
Pre-rRNA-processing protein IPI3

14

1

Small-scale

0.761

High

806613

NUG1
Nuclear GTP-binding protein NUG1

13

1

Small-scale

0.756

High

806638

NOG2
Nucleolar GTP-binding protein 2

11

1

Small-scale

0.753

High

806648

NOG1
Nucleolar GTP-binding protein 1

16

0

Small-scale

0.729

High

804985

IPI1
Pre-rRNA-processing protein IPI1

14

0

Small-scale

0.728

High

750080

MRT4
Ribosome assembly factor MRT4

6

1

Small-scale

0.726

High

806636

PESC
Pescadillo homolog

14

0

Small-scale

0.726

High

673564

NLE1
Ribosome assembly protein 4

12

0

Small-scale

0.725

High

806651

ARX1
Probable metalloprotease ARX1

11

0

Small-scale

0.723

High

570013

RL3
Large ribosomal subunit protein uL3

10

0

Small-scale

0.722

High

806674

MDN1
Midasin

9

0

Small-scale

0.721

High

806682

IF6
Eukaryotic translation initiation factor 6

9

0

Small-scale

0.721

High

806614

NSA2
Ribosome biogenesis protein NSA2

10

0

Small-scale

0.720

High

806666

BUD20
Bud site selection protein 20

8

0

Small-scale

0.719

High

806637

SDA1
Protein SDA1

8

0

Small-scale

0.715

High

682275

SPB4
ATP-dependent rRNA helicase SPB4

5

1

Small-scale

0.709

High

803859

CIC1
Proteasome-interacting protein CIC1

6

0

Small-scale

0.697

High

806676

NOP53
Ribosome biogenesis protein NOP53

6

0

Small-scale

0.688

High

806664

NOC3
Nucleolar complex-associated protein 3

4

1

Small-scale

0.686

High

806640

NOP15
Ribosome biogenesis protein 15

5

0

Small-scale

0.686

High

806628

ALB1
Ribosome biogenesis protein ALB1

5

0

Small-scale

0.684

High

782332

RPF2
Ribosome biogenesis protein RPF2

5

0

Small-scale

0.679

High

806650

HAS1
ATP-dependent RNA helicase HAS1

4

1

Small-scale

0.676

High

684722

RL5
Large ribosomal subunit protein uL18

5

0

Small-scale

0.676

High

515256

RL35A
Large ribosomal subunit protein uL29A

5

0

Small-scale

0.672

High

806665

RLP24
Ribosome biogenesis protein RLP24

7

2

Small-scale

0.671

High

531735

RL4A
Large ribosomal subunit protein uL4A

3

1

Small-scale

0.633

High

806656

ERB1
Ribosome biogenesis protein ERB1

3

0

Small-scale

0.613

High

433635

RL26A
Large ribosomal subunit protein uL24A

2

1

Small-scale

0.611

High

806660

ATG17
Autophagy-related protein 17

2

0

High-throughput

0.594

High

410126

RL25
Large ribosomal subunit protein uL23

2

0

Small-scale

0.585

High

806673

NIP7
60S ribosome subunit biogenesis protein NIP7

2

0

High-throughput

0.585

High

523914

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.584

High

677200

SPB1
27S pre-rRNA

2

1

Small-scale

0.584

High

689031

RL16A
Large ribosomal subunit protein uL13A

2

1

Small-scale

0.584

High

806680

MAK21
Ribosome biogenesis protein MAK21

2

2

Small-scale

0.584

High

544837

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.571

High

792039

GBLP
Small ribosomal subunit protein RACK1

2

1

High-throughput

0.571

High

435083

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.559

High

504207

RL31A
Large ribosomal subunit protein eL31A

2

0

Small-scale

0.559

High

601043

RL8A
Large ribosomal subunit protein eL8A

2

0

Small-scale

0.559

High

806622

NOP2
25S rRNA

2

0

Small-scale

0.559

High

806633

CGR1
rRNA-processing protein CGR1

2

0

Small-scale

0.559

High

806655

PUF6
Pumilio homology domain family member 6

2

0

Small-scale

0.547

High

806657

RRP5
rRNA biogenesis protein RRP5

2

0

Small-scale

0.547

High

754472

RT05
Small ribosomal subunit protein uS5m

2

1

High-throughput

0.537

High

806668

BRX1
Ribosome biogenesis protein BRX1

1

1

High-throughput

0.536

High

806644

NOP3
Serine/arginine

1

1

Small-scale

0.515

High

381514

H2B2
Histone H2B.2

1

0

High-throughput

0.513

High

700004

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.513

High

792517

RL32
Large ribosomal subunit protein eL32

1

0

Small-scale

0.513

High

806124

NMD3
60S ribosomal export protein NMD3

1

0

Small-scale

0.513

High

806623

RL10
Large ribosomal subunit protein uL16

1

0

Small-scale

0.513

High

806619

MSL1
U2 small nuclear ribonucleoprotein B''

1

0

High-throughput

0.486

High

416429

HXKA
Hexokinase-1

1

0

High-throughput

0.479

High

486169

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.479

High

626728

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.479

High

806641

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.479

High

409729

RL24A
Large ribosomal subunit protein eL24A

1

2

Small-scale

0.479

High

427272

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.479

High

513500

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

663674

RL24B
Large ribosomal subunit protein eL24B

1

2

Small-scale

0.479

High

674619

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

689211

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.479

High

694542

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.479

High

791056

NOP4
Nucleolar protein 4

1

1

Small-scale

0.479

High

806661

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

806675

YTM1
Ribosome biogenesis protein YTM1

1

1

Small-scale

0.479

High

149757

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383697

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

403508

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.458

High

432839

RL9A
Large ribosomal subunit protein uL6A

1

0

Small-scale

0.458

High

433204

RL17A
Large ribosomal subunit protein uL22A

1

0

Small-scale

0.458

High

435960

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

436407

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

441903

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

455058

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

503039

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

503388

RL11A
Large ribosomal subunit protein uL5A

1

0

Small-scale

0.458

High

503791

RL27A
Large ribosomal subunit protein eL27A

1

0

Small-scale

0.458

High

511197

RL20B
Large ribosomal subunit protein eL20B

1

0

Small-scale

0.458

High

511419

RL43B
Large ribosomal subunit protein eL43B

1

0

Small-scale

0.458

High

512435

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513004

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

513364

RL23B
Large ribosomal subunit protein uL14B

1

0

Small-scale

0.458

High

513684

RL2A
Large ribosomal subunit protein uL2A

1

0

Small-scale

0.458

High

513997

RL18B
Large ribosomal subunit protein eL18B

1

0

Small-scale

0.458

High

514286

RL12B
Large ribosomal subunit protein uL11B

1

0

Small-scale

0.458

High

514634

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

579367

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

594361

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

647105

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

670264

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.458

High

670692

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

677392

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

689449

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

707066

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

734974

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747354

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

753365

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

778325

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

780262

EBP2
rRNA-processing protein EBP2

1

0

Small-scale

0.458

High

781189

RL14A
Large ribosomal subunit protein eL14A

1

0

Small-scale

0.458

High

782161

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

794981

NU170
Nucleoporin NUP170

1

0

High-throughput

0.458

High

795816

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

798214

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.458

High

802166

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

806609

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

806610

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

806612

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.458

High

806618

BMT5
25S rRNA

1

0

High-throughput

0.458

High

806629

MTR4
ATP-dependent RNA helicase DOB1

1

0

Small-scale

0.458

High

806630

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

806632

NSA1
Ribosome biogenesis protein NSA1

1

0

High-throughput

0.458

High

806642

H3
Histone H3

1

0

High-throughput

0.458

High

806645

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

806647

RL6A
Large ribosomal subunit protein eL6A

1

0

Small-scale

0.458

High

806649

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

806653

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

806654

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.458

High

806659

FKBP4
FK506-binding protein 4

1

0

Small-scale

0.458

High

806669

SGO1
Shugoshin

1

0

High-throughput

0.458

High

806670

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

806671

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

806672

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.458

High

806677

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

806679

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

526666

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

645731

HSP74
Heat shock protein SSA4

1

2

High-throughput

0.445

High

741560

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

806615

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

806616

RL13B
Large ribosomal subunit protein eL13B

1

1

Small-scale

0.445

High

806631

RL4B
Large ribosomal subunit protein uL4B

1

1

Small-scale

0.445

High

806634

RL26B
Large ribosomal subunit protein uL24B

1

1

Small-scale

0.445

High

806683

RL13A
Large ribosomal subunit protein eL13A

1

1

Small-scale

0.445

High

806624

GLDS1
Protein GDS1

1

0

High-throughput

0.438

High

806626

ZNF1
Respiratory transcription factor ZNF1

1

0

High-throughput

0.438

High

806662

RXT3
Transcriptional regulatory protein RXT3

1

0

High-throughput

0.438

High

806678

MED2
Mediator of RNA polymerase II transcription subunit 2

1

0

High-throughput

0.438

High

806681

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.438

High

619428

MED14
Mediator of RNA polymerase II transcription subunit 14

1

0

High-throughput

0.426

High

739961

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

High-throughput

0.426

High

744514

HBS1
Elongation factor 1 alpha-like protein

1

0

High-throughput

0.426

High

748257

VPS17
Vacuolar protein sorting-associated protein 17

1

0

High-throughput

0.426

High

806617

YIR7
Y' element ATP-dependent helicase YIL177C

1

1

High-throughput

0.407

High

806621

YJW5
Y' element ATP-dependent helicase YJL225C

1

1

High-throughput

0.407

High

806620

RLP7
Ribosome biogenesis protein RLP7

5

0

Small-scale

0.368

High

745081

AFG2
ATPase family gene 2 protein

2

0

High-throughput

0.305

High

676804

BUD3
Bud site selection protein 3

1

0

High-throughput

0.279

Low

793075

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

806652

YD131
F-box protein YDR131C

1

0

High-throughput

0.279

Low

613575

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.261

Low

365044

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.249

Low

806611

IMDH1
Putative inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.249

Low

806643

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

806663

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

806667

NOP12
Nucleolar protein 12

1

0

Small-scale

0.249

Low

806635

BUD9
Bud site selection protein 9

1

0

High-throughput

0.238

Low

806646

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

806658

ECI1
3,2-trans-enoyl-CoA isomerase

1

0

High-throughput

0.238

Low

598861

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.232

Low

617979

IRA1
Inhibitory regulator protein IRA1

1

0

High-throughput

0.232

Low

746488

BEM3
GTPase-activating protein BEM3

1

0

High-throughput

0.232

Low

752245

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

796569

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.232

Low

806625

AGP3
General amino acid permease AGP3

1

0

High-throughput

0.232

Low

806627

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025