Protein: SCS3
Acyl-coenzyme A diphosphatase SCS3 (EC 3.6.1.-) (FIT family protein SCS3)

Gene: SCS3
Organism: Saccharomyces cerevisiae S288C
Interactions: 77
UniProt ID: P53012

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0005789 - endoplasmic reticulum membrane
GO:0006644 - phospholipid metabolic process
GO:0008654 - phospholipid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

527191

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.521

High

793247

BAP2
Leu/Val/Ile amino-acid permease

1

3

Small-scale

0.481

High

793275

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

1

3

Small-scale

0.481

High

822191

CYB5
Cytochrome b5

1

1

Small-scale

0.481

High

877845

GNP1
High-affinity glutamine permease

1

3

Small-scale

0.481

High

916447

SCS7
Ceramide very long chain fatty acid hydroxylase SCS7

1

1

Small-scale

0.481

High

564753

ATC1
Calcium-transporting ATPase 1

1

0

Small-scale

0.460

High

645114

EPT1
Choline/ethanolaminephosphotransferase 1

1

0

Small-scale

0.460

High

663809

PPA3
Constitutive acid phosphatase

1

0

Small-scale

0.460

High

737577

ERG1
Squalene epoxidase ERG1

1

0

Small-scale

0.460

High

745368

EMP24
Endosomal protein P24B

1

0

Small-scale

0.460

High

794939

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

0

Small-scale

0.460

High

797004

PHO88
SRP-independent targeting protein 3

1

0

Small-scale

0.460

High

809027

STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

1

0

Small-scale

0.460

High

822263

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

0

Small-scale

0.460

High

826986

VLD1
Vacuole localized DSC protein 1

1

0

Small-scale

0.460

High

850933

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

Small-scale

0.460

High

916444

SLG1
Protein SLG1

1

0

Small-scale

0.460

High

916450

IZH3
ADIPOR-like receptor IZH3

1

0

Small-scale

0.460

High

916453

PCD1
Peroxisomal coenzyme A diphosphatase 1, peroxisomal

1

0

Small-scale

0.460

High

420962

PMA1
Plasma membrane ATPase 1

1

1

Small-scale

0.439

High

564785

ATN1
Sodium/potassium exporting P-type ATPase 1

1

1

Small-scale

0.439

High

737234

HXT1
Low-affinity glucose transporter HXT1

1

2

Small-scale

0.439

High

737274

HXT3
Low-affinity glucose transporter HXT3

1

2

Small-scale

0.439

High

737292

HXT4
Low-affinity glucose transporter HXT4

1

2

Small-scale

0.439

High

738002

LYP1
Lysine-specific permease

1

3

Small-scale

0.439

High

793875

FLR1
Fluconazole resistance protein 1

1

3

Small-scale

0.439

High

801079

FKS1
1,3-beta-glucan synthase component FKS1

1

1

Small-scale

0.439

High

816118

SIT1
Siderophore iron transporter 1

1

3

Small-scale

0.439

High

819272

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

Small-scale

0.439

High

830106

FKS2
1,3-beta-glucan synthase component GSC2

1

1

Small-scale

0.439

High

524575

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.437

High

545577

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

394733

EF1A
Elongation factor 1-alpha

2

0

Small-scale

0.300

High

836790

MPG1
Mannose-1-phosphate guanyltransferase

2

0

Small-scale

0.300

High

809157

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

High-throughput

0.265

Low

358280

ADH1
Alcohol dehydrogenase 1

1

0

Small-scale

0.251

Low

359502

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

0

Small-scale

0.251

Low

365660

PGK
Phosphoglycerate kinase

1

0

Small-scale

0.251

Low

416264

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

Small-scale

0.251

Low

416458

HXKA
Hexokinase-1

1

0

Small-scale

0.251

Low

419810

H2A2
Histone H2A.2

1

0

Small-scale

0.251

Low

464514

CHS1
Chitin synthase 1

1

0

Small-scale

0.251

Low

566513

DHAS
Aspartate-semialdehyde dehydrogenase

1

0

Small-scale

0.251

Low

585641

STI1
Heat shock protein STI1

1

0

Small-scale

0.251

Low

613607

ADT2
ADP,ATP carrier protein 2

1

0

Small-scale

0.251

Low

628272

ZRC1
Vacuolar zinc transporter ZRC1

1

0

Small-scale

0.251

Low

663612

VATO
V-type proton ATPase subunit c''

1

0

Small-scale

0.251

Low

668400

PSB2
Proteasome subunit beta type-2

1

0

Small-scale

0.251

Low

677010

ATG22
Autophagy-related protein 22

1

0

Small-scale

0.251

Low

712617

RL8B
Large ribosomal subunit protein eL8B

1

0

Small-scale

0.251

Low

713504

TRXB1
Thioredoxin reductase 1

1

0

Small-scale

0.251

Low

724341

DHOM
Homoserine dehydrogenase

1

0

Small-scale

0.251

Low

734755

RME1
Zinc finger protein RME1

1

0

Small-scale

0.251

Low

739413

ZUO1
Zuotin

1

0

Small-scale

0.251

Low

746244

PTM1
Membrane protein PTM1

1

0

Small-scale

0.251

Low

747094

PTR2
Peptide transporter PTR2

1

0

Small-scale

0.251

Low

751101

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

0

Small-scale

0.251

Low

763093

RRP1
Ribosomal RNA-processing protein 1

1

0

Small-scale

0.251

Low

777215

KES1
Oxysterol-binding protein homolog 4

1

0

Small-scale

0.251

Low

780620

CAB3
Coenzyme A biosynthesis protein 3

1

0

Small-scale

0.251

Low

782284

GTO2
Glutathione S-transferase omega-like 2

1

0

Small-scale

0.251

Low

813733

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

0

Small-scale

0.251

Low

865134

AVT1
Vacuolar amino acid transporter 1

1

0

Small-scale

0.251

Low

916441

YG37
Uncharacterized protein YGR127W

1

0

Small-scale

0.251

Low

916442

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

Small-scale

0.251

Low

916443

YN8Z
Uncharacterized vacuolar membrane protein YNR061C

1

0

Small-scale

0.251

Low

916445

ACT
Actin

1

0

Small-scale

0.251

Low

916446

H3
Histone H3

1

0

Small-scale

0.251

Low

916449

YPQ2
Vacuolar arginine/histidine antiporter YPQ2

1

0

Small-scale

0.251

Low

916452

NOP56
Nucleolar protein 56

1

0

Small-scale

0.251

Low

916451

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

382222

H4
Histone H4

1

0

High-throughput

0.232

Low

531808

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.232

Low

670930

SIS1
Protein SIS1

1

0

High-throughput

0.232

Low

817910

IMB4
Importin subunit beta-4

1

0

High-throughput

0.232

Low

916448

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025