Protein: WDR12
Ribosome biogenesis protein WDR12 (WD repeat-containing protein 12)

Gene: WDR12
Organism: Homo sapiens
Interactions: 98
UniProt ID: Q9GZL7

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0007219 - Notch signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

139603

PESC
Pescadillo homolog

11

4

Small-scale

0.977

High

1121081

BOP1
Ribosome biogenesis protein BOP1

6

20

Small-scale

0.943

High

1392233

DDX27
Probable ATP-dependent RNA helicase DDX27

2

20

Small-scale

0.789

High

1428134

ANLN
Anillin

2

5

High-throughput

0.754

High

1161656

IF16
Gamma-interferon-inducible protein 16

3

10

High-throughput

0.656

High

822852

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.630

High

288761

NPM3
Nucleoplasmin-3

2

10

High-throughput

0.628

High

447412

NPM
Nucleophosmin

2

10

High-throughput

0.628

High

998006

CSK21
Casein kinase II subunit alpha

2

13

High-throughput

0.628

High

1428132

WDR55
WD repeat-containing protein 55

2

15

High-throughput

0.628

High

194334

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.618

High

762048

GRK5
G protein-coupled receptor kinase 5

1

8

High-throughput

0.618

High

998781

H31
Histone H3.1

1

9

High-throughput

0.618

High

1316158

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

15

Small-scale

0.618

High

1428130

WDR12
Ribosome biogenesis protein WDR12

1

16

Small-scale

0.618

High

1428138

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

13

High-throughput

0.618

High

1428142

FBW1A
F-box/WD repeat-containing protein 1A

1

16

High-throughput

0.618

High

1418569

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

2

15

High-throughput

0.611

High

169270

CASQ2
Calsequestrin-2

3

9

High-throughput

0.609

High

396899

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1258384

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.557

High

157826

CTRO
Citron Rho-interacting kinase

1

8

High-throughput

0.553

High

419190

H2A1B
Histone H2A type 1-B/E

1

9

High-throughput

0.553

High

1255441

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.553

High

1428131

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

1428140

FBW1B
F-box/WD repeat-containing protein 11

1

16

High-throughput

0.553

High

187177

PPM1G
Protein phosphatase 1G

1

2

High-throughput

0.536

High

287125

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

20

High-throughput

0.536

High

625608

CSK22
Casein kinase II subunit alpha'

1

13

High-throughput

0.536

High

686410

RL13
Large ribosomal subunit protein eL13

1

5

High-throughput

0.536

High

807961

SMBP2
DNA-binding protein SMUBP-2

1

8

High-throughput

0.536

High

833182

MNDA
Myeloid cell nuclear differentiation antigen

1

10

High-throughput

0.536

High

1006691

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.536

High

1099241

SRSF5
Serine/arginine-rich splicing factor 5

1

20

High-throughput

0.536

High

1112164

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.536

High

1231660

RL7L
Ribosomal protein uL30-like

1

9

High-throughput

0.536

High

1428137

LYAR
Cell growth-regulating nucleolar protein

1

4

High-throughput

0.536

High

1428143

RL36
Large ribosomal subunit protein eL36

1

3

High-throughput

0.536

High

242853

PRKN
E3 ubiquitin-protein ligase parkin

2

14

High-throughput

0.533

High

1096215

TADBP
TAR DNA-binding protein 43

1

20

High-throughput

0.515

High

1227417

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.514

High

1361756

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

1390604

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

596337

H12
Histone H1.2

1

12

Small-scale

0.512

High

521925

H14
Histone H1.4

1

12

High-throughput

0.489

High

595863

H13
Histone H1.3

1

12

High-throughput

0.489

High

859988

RL28
Large ribosomal subunit protein eL28

1

2

High-throughput

0.489

High

1290036

PNM8A
Paraneoplastic antigen-like protein 8A

1

1

High-throughput

0.489

High

1428139

IL17B
Interleukin-17B

1

1

High-throughput

0.489

High

129404

MEN1
Menin

1

5

High-throughput

0.479

High

223314

PRC1
Protein regulator of cytokinesis 1

1

10

High-throughput

0.479

High

260425

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.479

High

274743

DNJB6
DnaJ homolog subfamily B member 6

1

14

High-throughput

0.479

High

373095

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

414574

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

473063

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

12

High-throughput

0.479

High

589629

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

637722

FLNA
Filamin-A

1

14

High-throughput

0.479

High

696442

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

765868

BMI1
Polycomb complex protein BMI-1

1

18

High-throughput

0.479

High

769116

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

810354

RL3
Large ribosomal subunit protein uL3

1

8

High-throughput

0.479

High

831390

CCNF
Cyclin-F

1

10

High-throughput

0.479

High

879445

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

937895

FOXA1
Hepatocyte nuclear factor 3-alpha

1

14

High-throughput

0.479

High

965223

WDR5
WD repeat-containing protein 5

1

18

Small-scale

0.479

High

979216

RS6
Small ribosomal subunit protein eS6

1

5

High-throughput

0.479

High

1035898

KIF23
Kinesin-like protein KIF23

1

12

High-throughput

0.479

High

1107185

BIRC3
Baculoviral IAP repeat-containing protein 3

1

6

High-throughput

0.479

High

1235515

IFIX
Pyrin and HIN domain-containing protein 1

1

10

High-throughput

0.479

High

1352736

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

1361229

DNJC9
DnaJ homolog subfamily C member 9

1

17

High-throughput

0.479

High

1367214

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1384872

CHCH1
Small ribosomal subunit protein mS37

1

1

High-throughput

0.479

High

1386570

OPTN
Optineurin

1

20

High-throughput

0.479

High

1393670

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1404748

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1428133

BRD7
Bromodomain-containing protein 7

1

13

High-throughput

0.479

High

1428135

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

6

High-throughput

0.479

High

1428136

MDN1
Midasin

1

15

Small-scale

0.479

High

1115411

CUL4B
Cullin-4B

1

20

High-throughput

0.445

High

1130440

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

11

High-throughput

0.445

High

1209630

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

High-throughput

0.445

High

106615

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

272448

OBSL1
Obscurin-like protein 1

1

10

High-throughput

0.437

High

346297

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.437

High

401451

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.437

High

731598

STIP1
Stress-induced-phosphoprotein 1

1

16

High-throughput

0.437

High

1140818

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.437

High

1178546

BLTP1
Bridge-like lipid transfer protein family member 1

1

1

High-throughput

0.437

High

1288247

LYRIC
Protein LYRIC

1

4

Small-scale

0.437

High

1290708

ZCH18
Zinc finger CCCH domain-containing protein 18

1

20

High-throughput

0.437

High

1385858

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.437

High

1428141

HECD1
E3 ubiquitin-protein ligase HECTD1

1

17

High-throughput

0.437

High

1329612

TMC5A
Transmembrane and coiled-coil domain-containing protein 5A

1

0

High-throughput

0.269

Low

1338357

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1397977

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025