Protein: NQO1
NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1)

Gene: NQO1
Organism: Homo sapiens
Interactions: 47
UniProt ID: P15559

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0002931 - response to ischemia
GO:0003723 - RNA binding
GO:0003955 - NAD(P)H dehydrogenase (quinone) activity
GO:0004128 - cytochrome-b5 reductase activity, acting on NAD(P)H

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548991

NQO1
NAD(P)H dehydrogenase [quinone] 1

4

2

Small-scale

0.891

High

386031

P53
Cellular tumor antigen p53

4

1

Small-scale

0.696

High

549018

CHIP
E3 ubiquitin-protein ligase CHIP

2

0

Small-scale

0.603

High

549010

HIF1A
Hypoxia-inducible factor 1-alpha

2

0

Small-scale

0.598

High

549009

NF2L2
Nuclear factor erythroid 2-related factor 2

2

1

Small-scale

0.584

High

432459

GALT
Galactose-1-phosphate uridylyltransferase

2

0

High-throughput

0.580

High

549013

SH2D3
SH2 domain-containing protein 3C

2

1

High-throughput

0.571

High

548994

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.561

High

373635

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

0

High-throughput

0.559

High

549002

GRB2
Growth factor receptor-bound protein 2

2

0

High-throughput

0.547

High

549004

CAV1
Caveolin-1

2

0

High-throughput

0.547

High

226431

PRKN
E3 ubiquitin-protein ligase parkin

1

0

Small-scale

0.537

High

549017

ING1
Inhibitor of growth protein 1

1

0

Small-scale

0.537

High

175636

TRI18
E3 ubiquitin-protein ligase Midline-1

1

2

High-throughput

0.536

High

128804

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

0

High-throughput

0.513

High

176373

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

High-throughput

0.513

High

258656

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.513

High

496226

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

549003

TIE2
Angiopoietin-1 receptor

1

0

High-throughput

0.513

High

549016

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

0

High-throughput

0.513

High

548998

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

0

Small-scale

0.480

High

549000

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

345306

FOS
Protein c-Fos

1

1

Small-scale

0.479

High

549001

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

549012

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

243873

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

324210

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

352473

TNFA
Tumor necrosis factor

1

0

High-throughput

0.458

High

455050

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.458

High

530401

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

548993

TYY1
Transcriptional repressor protein YY1

1

0

Small-scale

0.458

High

548995

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

548997

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

548999

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

549005

TRI26
Tripartite motif-containing protein 26

1

0

Small-scale

0.458

High

549006

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

Small-scale

0.458

High

549008

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

549011

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.458

High

549014

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

Small-scale

0.458

High

549015

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

175818

P73
Tumor protein p73

1

1

Small-scale

0.445

High

548996

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

548992

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.426

High

549007

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.426

High

329317

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

362778

FINC
Fibronectin

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024