Protein: GLRX1
Glutaredoxin-1 (Thioltransferase-1) (TTase-1)

Gene: GLRX1, GLRX
Organism: Homo sapiens
Interactions: 33
UniProt ID: P35754

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0015038 - glutathione disulfide oxidoreductase activity
GO:0015949 - nucleobase-containing small molecule interconversion
GO:0017080 - sodium channel regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

776880

CF298
Cilia- and flagella-associated protein 298

3

0

High-throughput

0.638

High

776896

TRI62
E3 ubiquitin-protein ligase TRIM62

2

0

High-throughput

0.580

High

776885

ATP7A
Copper-transporting ATPase 1

1

2

Small-scale

0.552

High

776875

CASP3
Caspase-3

1

0

High-throughput

0.518

High

776878

AQP5
Aquaporin-5

1

0

High-throughput

0.518

High

361857

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.513

High

390996

TRFL
Lactotransferrin

1

0

High-throughput

0.513

High

776898

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.513

High

775751

ATP7B
Copper-transporting ATPase 2

1

2

Small-scale

0.504

High

362011

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.486

High

776895

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

1

Small-scale

0.479

High

776897

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

776876

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

776877

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

776882

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

776886

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

776889

DET1
DET1 homolog

1

0

High-throughput

0.458

High

776891

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

776892

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

776893

COP1
E3 ubiquitin-protein ligase COP1

1

0

High-throughput

0.458

High

776879

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.445

High

379729

IGHA2
Immunoglobulin heavy constant alpha 2

1

0

High-throughput

0.426

High

776888

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

296865

MMP23
Matrix metalloproteinase-23

1

0

High-throughput

0.282

High

325295

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

776881

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.279

Low

776883

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

776887

CCD18
Coiled-coil domain-containing protein 18

1

0

High-throughput

0.279

Low

776894

CHUR
Protein Churchill

1

0

High-throughput

0.279

Low

377429

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

776890

WDR53
WD repeat-containing protein 53

1

0

High-throughput

0.249

Low

598697

ANFB
Natriuretic peptides B

1

0

High-throughput

0.232

Low

776884

TAGL
Transgelin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025