Protein: PAPD1
Poly(A) RNA polymerase, mitochondrial (PAP) (EC 2.7.7.19) (PAP-associated domain-containing protein 1) (Polynucleotide adenylyltransferase) (Terminal uridylyltransferase 1) (TUTase 1) (mtPAP)

Gene: PAPD1, MTPAP
Organism: Homo sapiens
Interactions: 147
UniProt ID: Q9NVV4

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0000965 - mitochondrial RNA 3'-end processing
GO:0002134 - UTP binding
GO:0003723 - RNA binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1025571

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

5

2

Small-scale

0.729

High

1346902

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

3

Small-scale

0.716

High

928490

DYL1
Dynein light chain 1, cytoplasmic

3

1

High-throughput

0.675

High

1018088

GRSF1
G-rich sequence factor 1

3

8

Small-scale

0.640

High

992714

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

1

High-throughput

0.628

High

1291307

DYL2
Dynein light chain 2, cytoplasmic

3

1

High-throughput

0.609

High

132036

VMA5A
von Willebrand factor A domain-containing protein 5A

2

0

High-throughput

0.602

High

1346907

TBK1
Serine/threonine-protein kinase TBK1

1

1

High-throughput

0.586

High

228867

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

1334560

LN28A
Protein lin-28 homolog A

1

9

High-throughput

0.575

High

1346919

EMIL1
EMILIN-1

2

1

High-throughput

0.574

High

370549

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

262999

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

1086823

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

815036

LEG7
Galectin-7

2

1

High-throughput

0.558

High

1051116

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.547

High

196209

RRP8
Ribosomal RNA-processing protein 8

1

2

High-throughput

0.536

High

269907

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

9

High-throughput

0.536

High

273277

SURF6
Surfeit locus protein 6

1

2

High-throughput

0.536

High

418716

NPM
Nucleophosmin

1

2

High-throughput

0.536

High

649778

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.536

High

1077139

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.536

High

1297030

ANM6
Protein arginine N-methyltransferase 6

1

1

High-throughput

0.536

High

1346910

HECD1
E3 ubiquitin-protein ligase HECTD1

2

4

Small-scale

0.533

High

272395

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.513

High

1079700

ADIPO
Adiponectin

1

0

High-throughput

0.513

High

1159949

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

1254671

HUMMR
Protein MGARP

1

0

High-throughput

0.513

High

1333344

GEMI7
Gem-associated protein 7

1

0

High-throughput

0.513

High

1333657

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

1346912

LAMP3
Lysosome-associated membrane glycoprotein 3

1

0

High-throughput

0.513

High

1346915

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1346917

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

0

High-throughput

0.513

High

1346918

EID1
EP300-interacting inhibitor of differentiation 1

1

0

High-throughput

0.513

High

787981

EPS15
Epidermal growth factor receptor substrate 15

1

2

High-throughput

0.501

High

1346908

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

High-throughput

0.493

High

121219

LEG8
Galectin-8

1

1

High-throughput

0.489

High

208949

FOXS1
Forkhead box protein S1

1

1

High-throughput

0.489

High

296489

ACL6B
Actin-like protein 6B

1

1

High-throughput

0.489

High

473608

DC8L2
DDB1- and CUL4-associated factor 8-like protein 2

1

3

High-throughput

0.489

High

1169832

FOXI2
Forkhead box protein I2

1

1

High-throughput

0.489

High

833823

CLK1
Dual specificity protein kinase CLK1

1

2

High-throughput

0.481

High

131614

STK25
Serine/threonine-protein kinase 25

1

1

High-throughput

0.479

High

270137

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

327584

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

1

High-throughput

0.479

High

348033

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

374966

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

440766

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.479

High

553866

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

582524

NUCL
Nucleolin

1

4

High-throughput

0.479

High

587721

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

High-throughput

0.479

High

595439

LMNB1
Lamin-B1

1

7

High-throughput

0.479

High

652406

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

803254

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

818519

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

824442

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

941492

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

959708

VIGLN
Vigilin

1

6

High-throughput

0.479

High

983682

FAK1
Focal adhesion kinase 1

1

2

High-throughput

0.479

High

1020588

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.479

High

1029938

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

1042653

CUL3
Cullin-3

1

6

High-throughput

0.479

High

1071707

KS6A2
Ribosomal protein S6 kinase alpha-2

1

2

High-throughput

0.479

High

1073487

KS6A1
Ribosomal protein S6 kinase alpha-1

1

2

High-throughput

0.479

High

1184060

DHX30
ATP-dependent RNA helicase DHX30

1

2

High-throughput

0.479

High

1185390

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

2

High-throughput

0.479

High

1233467

NIN
Ninein

1

1

High-throughput

0.479

High

1269745

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1282859

FAKD4
FAST kinase domain-containing protein 4

1

2

High-throughput

0.479

High

1287401

OPTN
Optineurin

1

3

High-throughput

0.479

High

1301163

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

1326531

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

4

High-throughput

0.479

High

1330103

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1330859

Q9H4D1
Protein kinase

1

1

High-throughput

0.479

High

1343685

ANLN
Anillin

1

2

High-throughput

0.479

High

1346903

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

2

High-throughput

0.479

High

1346905

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1346906

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1346909

HOOK1
Protein Hook homolog 1

1

1

High-throughput

0.479

High

59329

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

173130

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

182925

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

486661

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

790033

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

799385

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

881686

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

959068

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

981455

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1128273

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1201710

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1289012

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1289151

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1300400

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1329492

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1329813

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1333108

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1346904

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1346911

DIM1
Probable dimethyladenosine transferase

1

0

High-throughput

0.458

High

1346916

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

402537

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

883651

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

120668

RHOD
Rho-related GTP-binding protein RhoD

1

6

High-throughput

0.437

High

125751

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.437

High

164490

TRI66
Tripartite motif-containing protein 66

1

2

High-throughput

0.437

High

256099

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.437

High

319350

BRD1
Bromodomain-containing protein 1

1

3

High-throughput

0.437

High

545652

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.437

High

719637

MERL
Merlin

1

1

High-throughput

0.437

High

780194

CCNF
Cyclin-F

1

2

High-throughput

0.437

High

852644

RND2
Rho-related GTP-binding protein RhoN

1

5

High-throughput

0.437

High

894500

CDC42
Cell division control protein 42 homolog

1

4

High-throughput

0.437

High

900968

RHOA
Transforming protein RhoA

1

4

High-throughput

0.437

High

951393

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.437

High

1076785

RHOH
Rho-related GTP-binding protein RhoH

1

4

High-throughput

0.437

High

1140806

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.437

High

1146886

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.437

High

1171958

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1188937

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1202468

HOOK3
Protein Hook homolog 3

1

1

High-throughput

0.437

High

1232703

FBXW8
F-box/WD repeat-containing protein 8

1

1

High-throughput

0.437

High

1330945

RHOJ
Rho-related GTP-binding protein RhoJ

1

4

High-throughput

0.437

High

1331435

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

1335337

RHOF
Rho-related GTP-binding protein RhoF

1

5

High-throughput

0.437

High

1346914

NINL
Ninein-like protein

1

1

High-throughput

0.437

High

832873

TSP3
Thrombospondin-3

3

0

High-throughput

0.347

High

516155

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.328

High

885909

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.328

High

1332471

AZI2
5-azacytidine-induced protein 2

1

0

High-throughput

0.301

High

172255

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.279

Low

181355

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.279

Low

648622

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

1232089

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1237384

TSYL6
Testis-specific Y-encoded-like protein 6

1

0

High-throughput

0.279

Low

1243252

DDHD1
Phospholipase DDHD1

1

0

High-throughput

0.279

Low

1253044

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1264552

ATG4A
Cysteine protease ATG4A

1

0

High-throughput

0.279

Low

1295370

ZN333
Zinc finger protein 333

1

0

High-throughput

0.279

Low

1346913

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.279

Low

1297720

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.251

Low

352278

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

928697

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.249

Low

1101333

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1294062

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1302864

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.249

Low

1335580

SACA1
Sperm acrosome membrane-associated protein 1

1

0

High-throughput

0.249

Low

2122

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024