Protein: MKLN1
Muskelin

Gene: MKLN1
Organism: Homo sapiens
Interactions: 115
UniProt ID: Q9UL63

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0001726 - ruffle
GO:0002090 - regulation of receptor internalization
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1356791

MKLN1
Muskelin

3

17

Small-scale

0.843

High

1301828

RANB9
Ran-binding protein 9

8

8

Small-scale

0.753

High

1333468

RMD5A
E3 ubiquitin-protein transferase RMND5A

6

5

Small-scale

0.733

High

1241209

KCTD6
BTB/POZ domain-containing protein KCTD6

1

2

High-throughput

0.691

High

1347494

GID8
Glucose-induced degradation protein 8 homolog

3

6

Small-scale

0.674

High

1216860

ARMC8
Armadillo repeat-containing protein 8

3

3

High-throughput

0.667

High

1185167

MAEA
E3 ubiquitin-protein transferase MAEA

3

6

Small-scale

0.660

High

1332983

WDR26
WD repeat-containing protein 26

3

12

Small-scale

0.656

High

318032

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

2

5

High-throughput

0.628

High

1033758

IKZF1
DNA-binding protein Ikaros

2

2

High-throughput

0.628

High

1167191

RBP10
Ran-binding protein 10

2

6

High-throughput

0.611

High

448897

MMP7
Matrilysin

3

1

High-throughput

0.609

High

533103

PRG2
Bone marrow proteoglycan

3

1

High-throughput

0.609

High

1235698

ZBTB2
Zinc finger and BTB domain-containing protein 2

2

3

High-throughput

0.606

High

1289228

ZMY19
Zinc finger MYND domain-containing protein 19

2

0

High-throughput

0.602

High

1028218

GPS2
G protein pathway suppressor 2

2

0

High-throughput

0.585

High

1218053

GID4
Glucose-induced degradation protein 4 homolog

2

0

Small-scale

0.585

High

1314755

CYREN
Cell cycle regulator of non-homologous end joining

2

0

High-throughput

0.580

High

1245575

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

2

2

High-throughput

0.574

High

1293377

CC120
Coiled-coil domain-containing protein 120

2

1

High-throughput

0.574

High

1350545

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

2

2

High-throughput

0.574

High

1356792

PRG3
Proteoglycan 3

2

1

High-throughput

0.574

High

206434

LTOR5
Ragulator complex protein LAMTOR5

1

1

High-throughput

0.541

High

204085

HTRA2
Serine protease HTRA2, mitochondrial

1

1

High-throughput

0.536

High

473812

R10B1
Radial spoke head 10 homolog B

1

1

High-throughput

0.536

High

737524

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.536

High

818596

SOX2
Transcription factor SOX-2

1

8

High-throughput

0.536

High

869428

HAP1
Huntingtin-associated protein 1

1

9

High-throughput

0.536

High

1044891

AAMP
Angio-associated migratory cell protein

1

7

High-throughput

0.536

High

1051711

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

High-throughput

0.536

High

1167498

CRDL2
Chordin-like protein 2

1

2

High-throughput

0.536

High

1253142

PMFBP
Polyamine-modulated factor 1-binding protein 1

1

12

High-throughput

0.536

High

1307551

GDF15
Growth/differentiation factor 15

1

1

High-throughput

0.536

High

1308894

DDX50
ATP-dependent RNA helicase DDX50

1

3

High-throughput

0.536

High

1344106

DBLOH
Diablo IAP-binding mitochondrial protein

1

1

High-throughput

0.536

High

1345671

EMIL3
EMILIN-3

1

13

High-throughput

0.536

High

1049450

MORC3
MORC family CW-type zinc finger protein 3

1

0

High-throughput

0.518

High

348207

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.515

High

1070690

RNPS1
RNA-binding protein with serine-rich domain 1

1

2

High-throughput

0.515

High

1284159

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.515

High

159775

LECT2
Leukocyte cell-derived chemotaxin-2

1

0

High-throughput

0.513

High

238512

CST8
Cystatin-8

1

0

High-throughput

0.513

High

254018

MTG16
Protein CBFA2T3

1

0

High-throughput

0.513

High

259188

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

High-throughput

0.513

High

351469

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.513

High

445958

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.513

High

521316

SKI
Ski oncogene

1

0

High-throughput

0.513

High

1289722

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1330172

MMAD
Cobalamin trafficking protein CblD

1

0

High-throughput

0.513

High

131799

LAD1
Ladinin-1

1

2

High-throughput

0.489

High

611598

GNLY
Granulysin

1

1

High-throughput

0.489

High

725903

SOAT1
Sterol O-acyltransferase 1

1

1

High-throughput

0.489

High

799578

MMP13
Collagenase 3

1

1

High-throughput

0.489

High

1295293

JPH4
Junctophilin-4

1

1

High-throughput

0.489

High

1312641

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.489

High

1316141

ANGL4
Angiopoietin-related protein 4

1

1

High-throughput

0.489

High

1326586

WN10A
Protein Wnt-10a

1

1

High-throughput

0.489

High

1335920

SPON1
Spondin-1

1

1

High-throughput

0.489

High

1349256

HPBP1
Hsp70-binding protein 1

1

3

High-throughput

0.489

High

1355444

IL17B
Interleukin-17B

1

2

High-throughput

0.489

High

1355480

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

2

High-throughput

0.489

High

1355549

TCAL9
Transcription elongation factor A protein-like 9

1

1

High-throughput

0.489

High

1356758

PNMA2
Paraneoplastic antigen Ma2

1

2

High-throughput

0.489

High

151249

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

9

High-throughput

0.479

High

233912

HBP1
HMG box-containing protein 1

1

7

High-throughput

0.479

High

334307

LDHA
L-lactate dehydrogenase A chain

1

1

Small-scale

0.479

High

538057

KPYM
Pyruvate kinase PKM

1

1

Small-scale

0.479

High

554033

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

764756

GDNF
Glial cell line-derived neurotrophic factor

1

1

High-throughput

0.479

High

909313

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.479

High

980957

TLE4
Transducin-like enhancer protein 4

1

10

High-throughput

0.479

High

1025274

NR1H3
Oxysterols receptor LXR-alpha

1

10

High-throughput

0.479

High

1061677

CUL7
Cullin-7

1

3

High-throughput

0.479

High

1172226

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

1261446

NUDC2
NudC domain-containing protein 2

1

20

High-throughput

0.479

High

1291948

RMD5B
E3 ubiquitin-protein transferase RMND5B

1

5

High-throughput

0.479

High

1332757

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

1354150

HDAC6
Histone deacetylase 6

1

5

Small-scale

0.479

High

526692

GILT
Gamma-interferon-inducible lysosomal thiol reductase

1

0

High-throughput

0.458

High

894823

RAB8A
Ras-related protein Rab-8A

1

0

High-throughput

0.458

High

914900

YPEL5
Protein yippee-like 5

1

0

High-throughput

0.458

High

963700

E2F1
Transcription factor E2F1

1

4

High-throughput

0.445

High

1222635

SLX4
Structure-specific endonuclease subunit SLX4

1

6

High-throughput

0.445

High

577477

PACA
Pituitary adenylate cyclase-activating polypeptide

1

1

High-throughput

0.437

High

881334

CTBP2
C-terminal-binding protein 2

1

1

High-throughput

0.437

High

1161016

SG11A
Sperm-associated antigen 11A

1

1

High-throughput

0.437

High

996172

SG11B
Sperm-associated antigen 11B

1

1

High-throughput

0.407

High

1127613

Q5JSZ1
TLE family member 4, transcriptional corepressor

1

2

High-throughput

0.407

High

382645

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

3

0

High-throughput

0.347

High

526927

TDGF1
Protein Cripto

3

0

High-throughput

0.347

High

1116932

GRPL2
GLIPR1-like protein 2

3

0

High-throughput

0.347

High

1271377

GGH
Gamma-glutamyl hydrolase

3

0

High-throughput

0.347

High

1293535

SFRP2
Secreted frizzled-related protein 2

3

0

High-throughput

0.347

High

1316591

RM04
Large ribosomal subunit protein uL4m

3

0

High-throughput

0.347

High

528144

BMP1
Bone morphogenetic protein 1

2

0

High-throughput

0.328

High

1120130

TIGD5
Tigger transposable element-derived protein 5

2

0

High-throughput

0.328

High

1281763

PIGT
GPI transamidase component PIG-T

2

0

High-throughput

0.328

High

1356795

INSL6
Insulin-like peptide INSL6

2

0

High-throughput

0.328

High

1347561

HPF1
Histone PARylation factor 1

2

0

High-throughput

0.319

High

261926

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.279

Low

295895

LY6H
Lymphocyte antigen 6H

1

0

High-throughput

0.279

Low

351835

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

1

0

High-throughput

0.279

Low

873769

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.279

Low

1102668

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1218248

NNRD
ATP-dependent

1

0

High-throughput

0.279

Low

1246406

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.279

Low

1289918

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.279

Low

1328197

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.279

Low

1332870

GREM2
Gremlin-2

1

0

High-throughput

0.279

Low

1355715

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1356793

RT02
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.279

Low

1356794

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

1

0

High-throughput

0.279

Low

793167

PE2R3
Prostaglandin E2 receptor EP3 subtype

1

0

Small-scale

0.275

Low

1316809

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024