Protein: CLC7A
C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (CD antigen CD369)

Gene: CLC7A, CLEC7A
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q9BXN2

Gene Ontology (top 5):
GO:0001775 - cell activation
GO:0001872 - (1->3)-beta-D-glucan binding
GO:0001878 - response to yeast
GO:0001879 - detection of yeast
GO:0002223 - stimulatory C-type lectin receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1417127

CLC7A
C-type lectin domain family 7 member A

3

16

High-throughput

0.861

High

1417128

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

15

High-throughput

0.817

High

456007

ASGR2
Asialoglycoprotein receptor 2

2

15

High-throughput

0.783

High

688621

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

2

17

High-throughput

0.783

High

1417131

VISTA
V-type immunoglobulin domain-containing suppressor of T-cell activation

2

1

High-throughput

0.783

High

252371

TLR2
Toll-like receptor 2

2

7

Small-scale

0.754

High

239389

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

4

1

High-throughput

0.703

High

1092087

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

3

1

High-throughput

0.675

High

1417129

SMIM3
Small integral membrane protein 3

3

2

High-throughput

0.675

High

1065913

Q08AM2
ADAM33 protein

1

19

High-throughput

0.665

High

923477

PTTG
Pituitary tumor-transforming gene 1 protein-interacting protein

3

0

High-throughput

0.646

High

139305

UPK2
Uroplakin-2

2

2

High-throughput

0.606

High

188987

TMPS2
Transmembrane protease serine 2

2

5

High-throughput

0.606

High

211946

SPIT1
Kunitz-type protease inhibitor 1

2

15

High-throughput

0.606

High

327429

ZFPL1
Zinc finger protein-like 1

2

2

High-throughput

0.606

High

407128

HG2A
HLA class II histocompatibility antigen gamma chain

2

2

High-throughput

0.606

High

553371

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

11

High-throughput

0.606

High

622101

CD53
Leukocyte surface antigen CD53

2

14

High-throughput

0.606

High

770910

OPRM
Mu-type opioid receptor

2

3

High-throughput

0.606

High

800315

INGR2
Interferon gamma receptor 2

2

4

High-throughput

0.606

High

1059101

CXCL9
C-X-C motif chemokine 9

2

5

High-throughput

0.606

High

1159175

SGCB
Beta-sarcoglycan

2

3

High-throughput

0.606

High

1195546

CTXN3
Cortexin-3

2

2

High-throughput

0.606

High

1249434

OLFM4
Olfactomedin-4

2

5

High-throughput

0.606

High

1348783

FNDC9
Fibronectin type III domain-containing protein 9

2

3

High-throughput

0.606

High

1396494

SUSD3
Sushi domain-containing protein 3

2

1

High-throughput

0.606

High

193301

SOCS1
Suppressor of cytokine signaling 1

2

5

Small-scale

0.584

High

849241

KSYK
Tyrosine-protein kinase SYK

2

8

Small-scale

0.584

High

1329392

TEX29
Testis-expressed protein 29

2

0

High-throughput

0.580

High

1331501

NRAC
Nutritionally-regulated adipose and cardiac enriched protein homolog

2

0

High-throughput

0.580

High

1398470

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

1417135

NSG2
Neuronal vesicle trafficking-associated protein 2

2

0

High-throughput

0.580

High

1031679

ILRL1
Interleukin-1 receptor-like 1

1

10

High-throughput

0.573

High

1159823

OCLN
Occludin

1

2

High-throughput

0.573

High

1288776

KTN1
Kinectin

1

8

High-throughput

0.573

High

1417133

TMPS4
Transmembrane protease serine 4

1

5

High-throughput

0.573

High

1417134

NINJ2
Ninjurin-2

1

2

High-throughput

0.573

High

155617

NEMP1
Nuclear envelope integral membrane protein 1

2

1

High-throughput

0.553

High

464716

CXB1
Gap junction beta-1 protein

2

4

High-throughput

0.553

High

1187551

AR13B
ADP-ribosylation factor-like protein 13B

2

9

High-throughput

0.553

High

1394445

SC22A
Vesicle-trafficking protein SEC22a

2

6

High-throughput

0.553

High

1417132

SAR1A
Small COPII coat GTPase SAR1A

2

7

High-throughput

0.553

High

564330

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.541

High

1328195

JAGN1
Protein jagunal homolog 1

1

2

High-throughput

0.523

High

462610

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

4

High-throughput

0.515

High

1413919

Q9BU27
FAM3 metabolism regulating signaling molecule A

1

1

High-throughput

0.515

High

1270976

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.501

High

609791

LEG3
Galectin-3

1

12

Small-scale

0.500

High

532923

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.481

High

1023010

FAM3A
Protein FAM3A

1

10

High-throughput

0.481

High

1402286

RANB9
Ran-binding protein 9

1

1

High-throughput

0.481

High

477465

CD63
CD63 antigen

1

13

Small-scale

0.479

High

535920

CD37
Leukocyte antigen CD37

1

16

Small-scale

0.479

High

124834

AIP
AH receptor-interacting protein

1

0

High-throughput

0.460

High

1412306

TMM79
Transmembrane protein 79

4

0

High-throughput

0.364

High

1323882

SYNE4
Nesprin-4

2

0

High-throughput

0.334

High

1417130

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.316

High

1411443

Q9BRL5
Calmodulin

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025