Protein: MGST3
Glutathione S-transferase 3, mitochondrial (GST-3) (EC 2.5.1.-) (Glutathione peroxidase MGST3) (EC 1.11.1.-) (LTC4 synthase MGST3) (EC 4.4.1.20)

Gene: MGST3
Organism: Homo sapiens
Interactions: 239
UniProt ID: O14880

Gene Ontology (top 5):
GO:0004364 - glutathione transferase activity
GO:0004464 - leukotriene-C4 synthase activity
GO:0004602 - glutathione peroxidase activity
GO:0005635 - nuclear envelope
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

166810

MGST3
Glutathione S-transferase 3, mitochondrial

3

2

High-throughput

0.843

High

167006

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

3

1

High-throughput

0.667

High

166841

RASH
GTPase HRas

2

1

High-throughput

0.628

High

166812

BET1
BET1 homolog

2

2

High-throughput

0.606

High

166823

TSN2
Tetraspanin-2

2

4

High-throughput

0.606

High

166826

SC22B
Vesicle-trafficking protein SEC22b

2

2

High-throughput

0.606

High

166838

TSN12
Tetraspanin-12

2

4

High-throughput

0.606

High

166848

APOD
Apolipoprotein D

2

1

High-throughput

0.606

High

166866

PPLA
Phospholamban

2

1

High-throughput

0.606

High

166873

CTR1
High affinity cationic amino acid transporter 1

2

1

High-throughput

0.606

High

166882

EAA1
Excitatory amino acid transporter 1

2

1

High-throughput

0.606

High

166903

PLP2
Proteolipid protein 2

2

1

High-throughput

0.606

High

166918

VAMP3
Vesicle-associated membrane protein 3

2

2

High-throughput

0.606

High

166926

TTMP
TPA-induced transmembrane protein

2

1

High-throughput

0.606

High

166963

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.606

High

166966

GIMA1
GTPase IMAP family member 1

2

2

High-throughput

0.606

High

166967

AQP3
Aquaporin-3

2

4

High-throughput

0.606

High

166977

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

3

High-throughput

0.606

High

166985

AQP10
Aquaporin-10

2

5

High-throughput

0.606

High

167011

S39A9
Zinc transporter ZIP9

2

1

High-throughput

0.606

High

167024

STX8
Syntaxin-8

2

2

High-throughput

0.606

High

144377

SCD
Stearoyl-CoA desaturase

2

0

High-throughput

0.580

High

162131

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.580

High

166833

YIF1A
Protein YIF1A

2

0

High-throughput

0.580

High

166834

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.580

High

166843

TFR1
Transferrin receptor protein 1

2

0

High-throughput

0.580

High

166872

HMOX2
Heme oxygenase 2

2

0

High-throughput

0.580

High

166881

NSG1
Neuronal vesicle trafficking-associated protein 1

2

0

High-throughput

0.580

High

166896

S35A1
CMP-sialic acid transporter

2

0

High-throughput

0.580

High

166898

TFAM
Transcription factor A, mitochondrial

2

0

High-throughput

0.580

High

166915

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

2

0

High-throughput

0.580

High

166929

PLPP4
Phospholipid phosphatase 4

2

0

High-throughput

0.580

High

166931

LEMD1
LEM domain-containing protein 1

2

0

High-throughput

0.580

High

166932

MRM1
rRNA methyltransferase 1, mitochondrial

2

0

High-throughput

0.580

High

166936

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.580

High

166937

SNORC
Protein SNORC

2

0

High-throughput

0.580

High

166938

TM107
Transmembrane protein 107

2

0

High-throughput

0.580

High

166944

LRP10
Low-density lipoprotein receptor-related protein 10

2

0

High-throughput

0.580

High

166948

NRM
Nurim

2

0

High-throughput

0.580

High

166952

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.580

High

166955

T229B
Transmembrane protein 229B

2

0

High-throughput

0.580

High

166978

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.580

High

166980

CK024
Uncharacterized protein C11orf24

2

0

High-throughput

0.580

High

166984

FXDC2
Fatty acid hydroxylase domain-containing protein 2

2

0

High-throughput

0.580

High

166987

NEUR1
Sialidase-1

2

0

High-throughput

0.580

High

166992

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.580

High

166993

APOL2
Apolipoprotein L2

2

0

High-throughput

0.580

High

166995

FUND2
FUN14 domain-containing protein 2

2

0

High-throughput

0.580

High

167001

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.580

High

167002

TMM60
Transmembrane protein 60

2

0

High-throughput

0.580

High

167007

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

2

0

High-throughput

0.580

High

167008

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

2

0

High-throughput

0.580

High

167012

TM140
Transmembrane protein 140

2

0

High-throughput

0.580

High

167018

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.580

High

167023

ERG28
Ergosterol biosynthetic protein 28 homolog

2

0

High-throughput

0.580

High

167028

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

167035

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.580

High

166822

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

2

1

High-throughput

0.574

High

166871

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

2

1

High-throughput

0.574

High

166813

STX7
Syntaxin-7

2

1

High-throughput

0.553

High

166825

VAMP4
Vesicle-associated membrane protein 4

2

2

High-throughput

0.553

High

166862

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

2

1

High-throughput

0.553

High

166869

AQP1
Aquaporin-1

2

3

High-throughput

0.553

High

166870

MIP
Lens fiber major intrinsic protein

2

3

High-throughput

0.553

High

166910

STX3
Syntaxin-3

2

1

High-throughput

0.553

High

166946

TSN33
Tetraspanin-33

2

2

High-throughput

0.553

High

166962

GP152
Probable G-protein coupled receptor 152

2

2

High-throughput

0.553

High

166981

GIMA5
GTPase IMAP family member 5

2

2

High-throughput

0.553

High

167000

FXYD6
FXYD domain-containing ion transport regulator 6

2

1

High-throughput

0.553

High

167022

LPAR3
Lysophosphatidic acid receptor 3

2

3

High-throughput

0.553

High

166837

TSN15
Tetraspanin-15

1

2

High-throughput

0.536

High

166852

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

1

High-throughput

0.536

High

49718

TMM72
Transmembrane protein 72

1

0

High-throughput

0.513

High

160659

TOR1A
Torsin-1A

1

0

High-throughput

0.513

High

166847

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.513

High

166901

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

166902

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

0

High-throughput

0.513

High

166907

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.513

High

166919

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

166958

SVIP
Small VCP/p97-interacting protein

1

0

High-throughput

0.513

High

166960

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

166972

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.513

High

166973

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

0

High-throughput

0.513

High

166990

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.513

High

167021

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

167029

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

165854

FFAR1
Free fatty acid receptor 1

1

3

High-throughput

0.489

High

166865

EDNRA
Endothelin-1 receptor

1

1

High-throughput

0.489

High

166894

RAP1A
Ras-related protein Rap-1A

1

1

High-throughput

0.489

High

166935

S39A4
Zinc transporter ZIP4

1

1

High-throughput

0.489

High

166982

TSN17
Tetraspanin-17

1

3

High-throughput

0.489

High

167005

LPAR2
Lysophosphatidic acid receptor 2

1

3

High-throughput

0.489

High

166850

PPGB
Lysosomal protective protein

1

1

High-throughput

0.481

High

166819

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

166839

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

2

High-throughput

0.479

High

166845

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

166859

HXK1
Hexokinase-1

1

1

High-throughput

0.479

High

166861

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

2

High-throughput

0.479

High

166884

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

2

High-throughput

0.479

High

166889

HXK2
Hexokinase-2

1

1

High-throughput

0.479

High

166909

NDK3
Nucleoside diphosphate kinase 3

1

1

High-throughput

0.479

High

166969

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

167026

TDRKH
Tudor and KH domain-containing protein

1

1

High-throughput

0.479

High

166925

Q59EV6
Carboxypeptidase

1

1

High-throughput

0.470

High

166842

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

104843

APRIO
Alternative prion protein

1

0

High-throughput

0.458

High

135409

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.458

High

166811

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.458

High

166827

TACC1
Transforming acidic coiled-coil-containing protein 1

1

0

High-throughput

0.458

High

166830

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.458

High

166831

TOM70
Mitochondrial import receptor subunit TOM70

1

0

High-throughput

0.458

High

166832

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

166844

FRIL
Ferritin light chain

1

0

High-throughput

0.458

High

166846

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

166854

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.458

High

166855

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.458

High

166857

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

166858

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.458

High

166868

ABCD3
ATP-binding cassette sub-family D member 3

1

0

High-throughput

0.458

High

166874

GLPK
Glycerol kinase

1

0

High-throughput

0.458

High

166877

BASI
Basigin

1

0

High-throughput

0.458

High

166878

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

166886

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.458

High

166887

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

166888

PEX5
Peroxisomal targeting signal 1 receptor

1

0

High-throughput

0.458

High

166890

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.458

High

166900

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

0

High-throughput

0.458

High

166906

GOGA3
Golgin subfamily A member 3

1

0

High-throughput

0.458

High

166911

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

166916

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

166921

GLO2
Hydroxyacylglutathione hydrolase, mitochondrial

1

0

High-throughput

0.458

High

166922

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

166928

VP13D
Intermembrane lipid transfer protein VPS13D

1

0

High-throughput

0.458

High

166933

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

166934

MTFR2
Mitochondrial fission regulator 2

1

0

High-throughput

0.458

High

166940

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

0

High-throughput

0.458

High

166941

LARP4
La-related protein 4

1

0

High-throughput

0.458

High

166943

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.458

High

166945

CNTRL
Centriolin

1

0

High-throughput

0.458

High

166947

MIRO2
Mitochondrial Rho GTPase 2

1

0

High-throughput

0.458

High

166949

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.458

High

166950

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

166968

UBXN4
UBX domain-containing protein 4

1

0

High-throughput

0.458

High

166974

MARC2
Mitochondrial amidoxime reducing component 2

1

0

High-throughput

0.458

High

166976

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

166983

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

166996

B2L13
Bcl-2-like protein 13

1

0

High-throughput

0.458

High

166999

MFF
Mitochondrial fission factor

1

0

High-throughput

0.458

High

167009

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.458

High

167010

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

167013

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

167014

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.458

High

167016

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

167017

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.458

High

167030

HYOU1
Hypoxia up-regulated protein 1

1

0

High-throughput

0.458

High

167031

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.458

High

167032

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

0

High-throughput

0.458

High

166883

SATT
Neutral amino acid transporter A

1

1

High-throughput

0.445

High

166897

S35B1
Solute carrier family 35 member B1

1

1

High-throughput

0.445

High

166913

MFS10
Major facilitator superfamily domain-containing protein 10

1

1

High-throughput

0.445

High

166997

S12A9
Solute carrier family 12 member 9

1

2

High-throughput

0.445

High

167015

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.445

High

166820

NDK8
Putative nucleoside diphosphate kinase

1

1

High-throughput

0.437

High

166835

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.437

High

166998

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.437

High

840

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.426

High

166821

GSDME
Gasdermin-E

1

0

High-throughput

0.426

High

166849

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.426

High

166851

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

166863

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

166904

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.426

High

166959

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.426

High

167020

GRHL1
Grainyhead-like protein 1 homolog

1

0

High-throughput

0.426

High

167033

MPC1
Mitochondrial pyruvate carrier 1

1

0

High-throughput

0.426

High

167036

MTCH2
Mitochondrial carrier homolog 2

1

0

High-throughput

0.426

High

166885

GPR12
G-protein coupled receptor 12

1

2

High-throughput

0.407

High

156218

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

2

0

High-throughput

0.328

High

166971

GLMN
Glomulin

2

0

High-throughput

0.328

High

166988

S10AD
Protein S100-A13

2

0

High-throughput

0.328

High

49605

T120B
Transmembrane protein 120B

2

0

High-throughput

0.316

High

166828

PAGE1
P antigen family member 1

2

0

High-throughput

0.316

High

166836

BMP10
Bone morphogenetic protein 10

2

0

High-throughput

0.316

High

166853

ITAM
Integrin alpha-M

2

0

High-throughput

0.316

High

166891

CLRN1
Clarin-1

2

0

High-throughput

0.316

High

166893

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.316

High

166905

CCG1
Voltage-dependent calcium channel gamma-1 subunit

2

0

High-throughput

0.316

High

166912

GRM2
Metabotropic glutamate receptor 2

2

0

High-throughput

0.316

High

166920

NKG7
Protein NKG7

2

0

High-throughput

0.316

High

166924

UNC50
Protein unc-50 homolog

2

0

High-throughput

0.316

High

166927

SNP47
Synaptosomal-associated protein 47

2

0

High-throughput

0.316

High

166951

SYS1
Protein SYS1 homolog

2

0

High-throughput

0.316

High

166953

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

2

0

High-throughput

0.316

High

166954

NRAC
Nutritionally-regulated adipose and cardiac enriched protein homolog

2

0

High-throughput

0.316

High

166994

TM109
Voltage-gated monoatomic cation channel TMEM109

2

0

High-throughput

0.316

High

167019

NINJ2
Ninjurin-2

2

0

High-throughput

0.316

High

166864

CCNC
Cyclin-C

1

0

High-throughput

0.299

High

166917

KPCD1
Serine/threonine-protein kinase D1

2

0

High-throughput

0.298

High

166814

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.279

Low

166817

EFNA2
Ephrin-A2

1

0

High-throughput

0.279

Low

166818

KLK8
Kallikrein-8

1

0

High-throughput

0.279

Low

166824

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

166860

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.279

Low

166876

APJ
Apelin receptor

1

0

High-throughput

0.279

Low

166879

GPV
Platelet glycoprotein V

1

0

High-throughput

0.279

Low

166899

IRF9
Interferon regulatory factor 9

1

0

High-throughput

0.279

Low

166930

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

0

High-throughput

0.279

Low

166939

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

166961

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.279

Low

166986

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.279

Low

167025

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

167034

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.279

Low

166914

CLCA4
Calcium-activated chloride channel regulator 4

1

0

High-throughput

0.251

Low

125076

LEG9
Galectin-9

1

0

High-throughput

0.249

Low

166815

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

166816

MYO1B
Unconventional myosin-Ib

1

0

High-throughput

0.249

Low

166829

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

166856

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

166867

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

166875

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

166880

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

166892

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low

166895

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

166908

TP53B
TP53-binding protein 1

1

0

High-throughput

0.249

Low

166923

MIDN
Midnolin

1

0

High-throughput

0.249

Low

166942

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.249

Low

166956

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

166957

EHBP1
EH domain-binding protein 1

1

0

High-throughput

0.249

Low

166964

FBF1
Fas-binding factor 1

1

0

High-throughput

0.249

Low

166965

SMCR8
Guanine nucleotide exchange protein SMCR8

1

0

High-throughput

0.249

Low

166970

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.249

Low

166975

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.249

Low

166989

CDCA3
Cell division cycle-associated protein 3

1

0

High-throughput

0.249

Low

167003

WDR41
WD repeat-containing protein 41

1

0

High-throughput

0.249

Low

167004

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.249

Low

167027

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

166840

FA10
Coagulation factor X

1

0

High-throughput

0.238

Low

166979

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low

166991

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025