Protein: LRP3
Low-density lipoprotein receptor-related protein 3 (LRP-3) (105 kDa low-density lipoprotein receptor-related protein) (hLRp105)

Gene: LRP3
Organism: Homo sapiens
Interactions: 48
UniProt ID: O75074

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0005905 - clathrin-coated pit
GO:0006898 - receptor-mediated endocytosis
GO:0010628 - positive regulation of gene expression
GO:0010629 - negative regulation of gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

270186

LRP12
Low-density lipoprotein receptor-related protein 12

1

16

High-throughput

0.691

High

270182

EGFL7
Epidermal growth factor-like protein 7

1

19

High-throughput

0.618

High

270184

GGA1
ADP-ribosylation factor-binding protein GGA1

1

7

Small-scale

0.552

High

270145

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.541

High

270144

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

14

High-throughput

0.536

High

270147

EREP3
Protein ENTREP3

1

2

High-throughput

0.536

High

270149

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

1

High-throughput

0.536

High

270153

KCNT2
Potassium channel subfamily T member 2

1

6

High-throughput

0.536

High

270154

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

1

High-throughput

0.536

High

270160

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

1

High-throughput

0.536

High

270162

LMBR1
Limb region 1 protein homolog

1

1

High-throughput

0.536

High

270166

ASTRA
Protein Aster-A

1

2

High-throughput

0.536

High

270169

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

14

High-throughput

0.536

High

270176

TRPM3
Transient receptor potential cation channel subfamily M member 3

1

4

High-throughput

0.536

High

61066

T131L
Transmembrane protein 131-like

1

0

High-throughput

0.513

High

270142

FUT4
Alpha-(1,3)-fucosyltransferase 4

1

0

High-throughput

0.513

High

270143

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

1

0

High-throughput

0.513

High

270148

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.513

High

270177

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.513

High

270140

Z324A
Zinc finger protein 324A

1

13

High-throughput

0.489

High

270141

SUN1
SUN domain-containing protein 1

1

2

High-throughput

0.489

High

270150

MANEA
Glycoprotein endo-alpha-1,2-mannosidase

1

1

High-throughput

0.489

High

270152

Z324B
Zinc finger protein 324B

1

10

High-throughput

0.489

High

270157

ZN101
Zinc finger protein 101

1

11

High-throughput

0.489

High

270158

ZN444
Zinc finger protein 444

1

17

High-throughput

0.489

High

270164

SYNE2
Nesprin-2

1

4

High-throughput

0.489

High

270168

P121A
Nuclear envelope pore membrane protein POM 121

1

2

High-throughput

0.489

High

270170

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

6

High-throughput

0.489

High

270171

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

14

High-throughput

0.489

High

270173

EMIL2
EMILIN-2

1

19

High-throughput

0.489

High

270174

ZN696
Zinc finger protein 696

1

13

High-throughput

0.489

High

270175

DJC18
DnaJ homolog subfamily C member 18

1

6

High-throughput

0.489

High

270180

HECW2
E3 ubiquitin-protein ligase HECW2

1

14

High-throughput

0.489

High

270181

SUN2
SUN domain-containing protein 2

1

2

High-throughput

0.489

High

270146

SL9A3
Sodium/hydrogen exchanger 3

1

7

High-throughput

0.445

High

270163

CTL1
Choline transporter-like protein 1

1

1

High-throughput

0.445

High

270183

GGA2
ADP-ribosylation factor-binding protein GGA2

1

7

Small-scale

0.417

High

270156

ZN100
Zinc finger protein 100

1

0

High-throughput

0.279

Low

270159

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.279

Low

270161

ZN579
Zinc finger protein 579

1

0

High-throughput

0.279

Low

270165

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

270167

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.279

Low

270172

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

1

0

High-throughput

0.279

Low

270178

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

0

High-throughput

0.279

Low

270179

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.279

Low

270185

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.279

Low

270151

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.232

Low

270155

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025