Protein: CLNK
Cytokine-dependent hematopoietic cell linker (Mast cell immunoreceptor signal transducer)

Gene: CLNK
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q7Z7G1

Gene Ontology (top 5):
GO:0002729 - positive regulation of natural killer cell cytokine production
GO:0005737 - cytoplasm
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0032815 - negative regulation of natural killer cell activation
GO:0032991 - protein-containing complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

147529

SOCS6
Suppressor of cytokine signaling 6

2

20

High-throughput

0.767

High

655407

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

High-throughput

0.767

High

789028

TXK
Tyrosine-protein kinase TXK

2

20

High-throughput

0.743

High

802645

CRK
Adapter molecule crk

2

20

High-throughput

0.743

High

850750

BMX
Cytoplasmic tyrosine-protein kinase BMX

2

20

High-throughput

0.743

High

924670

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.743

High

1192754

RASF1
Ras association domain-containing protein 1

2

6

High-throughput

0.743

High

1031146

PTK7
Inactive tyrosine-protein kinase 7

2

20

High-throughput

0.686

High

1192751

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.686

High

338635

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

383868

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

890719

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.618

High

1073924

PP1R7
Protein phosphatase 1 regulatory subunit 7

2

1

High-throughput

0.594

High

1192753

STK36
Serine/threonine-protein kinase 36

2

4

High-throughput

0.576

High

1192755

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.576

High

1192757

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

2

3

High-throughput

0.576

High

1192746

RIP
RPA-interacting protein

2

0

High-throughput

0.569

High

1192749

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

2

0

High-throughput

0.551

High

135639

NDKM
Nucleoside diphosphate kinase, mitochondrial

2

2

High-throughput

0.542

High

1192756

SMBT1
Scm-like with four MBT domains protein 1

2

1

High-throughput

0.542

High

414327

RB
Retinoblastoma-associated protein

2

1

High-throughput

0.526

High

1192750

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

15

High-throughput

0.481

High

148005

C56D2
Transmembrane reductase CYB561D2

2

0

High-throughput

0.310

High

258474

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

0

High-throughput

0.310

High

1192747

F217A
Protein FAM217A

2

0

High-throughput

0.310

High

1192748

GLIS3
Zinc finger protein GLIS3

2

0

High-throughput

0.310

High

180056

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

2

0

High-throughput

0.300

High

1192752

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.300

High

1192758

ANR50
Ankyrin repeat domain-containing protein 50

2

0

High-throughput

0.300

High


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Last updated: 15 Jul 2024