Protein: VPS50
Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50)

Gene: VPS50
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q96JG6

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0015031 - protein transport
GO:0016020 - membrane
GO:0032456 - endocytic recycling
GO:0048471 - perinuclear region of cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1217274

VPS53
Vacuolar protein sorting-associated protein 53 homolog

7

6

Small-scale

0.751

High

1394942

VPS51
Vacuolar protein sorting-associated protein 51 homolog

7

3

Small-scale

0.750

High

1323325

VPS52
Vacuolar protein sorting-associated protein 52 homolog

6

6

Small-scale

0.738

High

1200061

EIPR1
EARP and GARP complex-interacting protein 1

6

2

Small-scale

0.733

High

774560

BASI
Basigin

3

2

High-throughput

0.667

High

1394940

VPS54
Vacuolar protein sorting-associated protein 54

3

1

High-throughput

0.667

High

343444

SNP29
Synaptosomal-associated protein 29

3

0

High-throughput

0.638

High

669051

FPR2
N-formyl peptide receptor 2

2

3

High-throughput

0.628

High

821758

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.602

High

1394936

S39A9
Zinc transporter ZIP9

2

0

High-throughput

0.602

High

1394937

EXOC1
Exocyst complex component 1

2

0

High-throughput

0.602

High

226171

STX6
Syntaxin-6

2

2

Small-scale

0.594

High

182728

GP182
G-protein coupled receptor 182

1

3

High-throughput

0.536

High

1394923

CML1
Chemerin-like receptor 1

1

3

High-throughput

0.536

High

136536

GOLI4
Golgi integral membrane protein 4

1

0

High-throughput

0.513

High

300680

KRT37
Keratin, type I cuticular Ha7

1

0

High-throughput

0.513

High

673787

LAMA1
Laminin subunit alpha-1

1

0

High-throughput

0.513

High

711731

RABP2
Cellular retinoic acid-binding protein 2

1

0

High-throughput

0.513

High

777540

K22E
Keratin, type II cytoskeletal 2 epidermal

1

0

High-throughput

0.513

High

1053050

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.513

High

1124886

FLOT2
Flotillin-2

1

0

High-throughput

0.513

High

1324845

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1394924

CAB45
45 kDa calcium-binding protein

1

0

High-throughput

0.513

High

1394925

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

0

High-throughput

0.513

High

1394935

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.513

High

1394939

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.513

High

1394947

RPGF2
Rap guanine nucleotide exchange factor 2

1

0

High-throughput

0.513

High

160912

STX16
Syntaxin-16

1

3

Small-scale

0.500

High

278545

VAMP4
Vesicle-associated membrane protein 4

1

2

Small-scale

0.500

High

1154708

VAMP3
Vesicle-associated membrane protein 3

1

2

Small-scale

0.500

High

1294810

STX12
Syntaxin-12

1

3

Small-scale

0.500

High

1383301

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

1

Small-scale

0.500

High

1361516

CTBL1
Beta-catenin-like protein 1

1

0

High-throughput

0.493

High

771207

APJ
Apelin receptor

1

2

High-throughput

0.489

High

914327

EFNA4
Ephrin-A4

1

1

High-throughput

0.489

High

1101630

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.489

High

1371351

TF3B
Transcription factor IIIB 90 kDa subunit

1

1

High-throughput

0.489

High

1394946

PSF2
DNA replication complex GINS protein PSF2

1

1

High-throughput

0.489

High

1394948

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

508446

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

189777

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

562316

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.479

High

630934

RAB4A
Ras-related protein Rab-4A

1

4

High-throughput

0.479

High

902006

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.479

High

976486

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

1227265

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1233418

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1276274

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

1394945

DD19B
ATP-dependent RNA helicase DDX19B

1

1

High-throughput

0.479

High

390730

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

791631

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

935007

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

965827

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

High-throughput

0.458

High

1110688

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

1196296

GRAP1
GRIP1-associated protein 1

1

0

High-throughput

0.458

High

1201148

CCD93
Coiled-coil domain-containing protein 93

1

0

High-throughput

0.458

High

1243035

PKN3
Serine/threonine-protein kinase N3

1

0

High-throughput

0.458

High

1348298

GOGA5
Golgin subfamily A member 5

1

0

High-throughput

0.458

High

1361996

RFFL
E3 ubiquitin-protein ligase rififylin

1

0

Small-scale

0.458

High

1394926

NUF2
Kinetochore protein Nuf2

1

0

High-throughput

0.458

High

1394927

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

High-throughput

0.458

High

1394943

RABX5
Rab5 GDP/GTP exchange factor

1

0

High-throughput

0.458

High

71465

P20L1
PHD finger protein 20-like protein 1

1

1

High-throughput

0.437

High

132759

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

1

High-throughput

0.437

High

192954

CLOCK
Circadian locomoter output cycles protein kaput

1

1

High-throughput

0.437

High

412443

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

1105377

SF3B2
Splicing factor 3B subunit 2

1

1

High-throughput

0.437

High

1241928

FBX42
F-box only protein 42

1

1

High-throughput

0.437

High

1384406

PF21A
PHD finger protein 21A

1

1

High-throughput

0.437

High

628445

KLK2
Kallikrein-2

1

0

High-throughput

0.426

High

107429

F8W9L8
PHD finger protein 20-like protein 1

1

1

High-throughput

0.407

High

114526

H0YEX5
Splicing factor 3b subunit 2

1

1

High-throughput

0.407

High

116313

H3BQK0
RNA helicase

1

1

High-throughput

0.407

High

1389784

DTBP1
Dysbindin

4

0

High-throughput

0.360

High

166392

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

2

0

High-throughput

0.288

High

185227

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.279

Low

214140

DHH
Desert hedgehog protein

1

0

High-throughput

0.279

Low

1056671

ZN33A
Zinc finger protein 33A

1

0

High-throughput

0.279

Low

1138942

R3HD1
R3H domain-containing protein 1

1

0

High-throughput

0.279

Low

1179839

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1310316

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1394922

OPALI
Opalin

1

0

High-throughput

0.279

Low

1394928

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.279

Low

1394929

PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3

1

0

High-throughput

0.279

Low

85300

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.249

Low

106466

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

128464

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.249

Low

174583

TRI66
Tripartite motif-containing protein 66

1

0

High-throughput

0.249

Low

217179

MS18B
Protein Mis18-beta

1

0

High-throughput

0.249

Low

246863

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.249

Low

340387

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.249

Low

342291

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

503648

TFPT
TCF3 fusion partner

1

0

High-throughput

0.249

Low

768901

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

959635

MAX
Protein max

1

0

High-throughput

0.249

Low

1088284

SFSWA
Splicing factor, suppressor of white-apricot homolog

1

0

High-throughput

0.249

Low

1122428

GIT2
ARF GTPase-activating protein GIT2

1

0

High-throughput

0.249

Low

1156574

CCDC6
Coiled-coil domain-containing protein 6

1

0

High-throughput

0.249

Low

1237915

PHLB3
Pleckstrin homology-like domain family B member 3

1

0

High-throughput

0.249

Low

1239912

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.249

Low

1255086

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1278428

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.249

Low

1294551

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

0

High-throughput

0.249

Low

1338321

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1350695

CCHCR
Coiled-coil alpha-helical rod protein 1

1

0

High-throughput

0.249

Low

1380919

P2R3C
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

1

0

High-throughput

0.249

Low

1389062

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.249

Low

1394920

SCLT1
Sodium channel and clathrin linker 1

1

0

High-throughput

0.249

Low

1394921

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

0

High-throughput

0.249

Low

1394930

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1394932

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.249

Low

1394933

TUFT1
Tuftelin

1

0

High-throughput

0.249

Low

1394934

HM20A
High mobility group protein 20A

1

0

High-throughput

0.249

Low

1394938

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

1394941

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1394944

RCOR1
REST corepressor 1

1

0

High-throughput

0.249

Low

1167101

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

1219531

ANR22
Ankyrin repeat domain-containing protein 22

1

0

High-throughput

0.232

Low

1394931

NRDE2
Nuclear exosome regulator NRDE2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025