Protein: ASCC2
Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100)

Gene: ASCC2
Organism: Homo sapiens
Interactions: 126
UniProt ID: Q9H1I8

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006307 - DNA alkylation repair
GO:0006355 - regulation of DNA-templated transcription
GO:0016607 - nuclear speck

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508605

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

4

1

Small-scale

0.888

High

1331964

ASCC1
Activating signal cointegrator 1 complex subunit 1

7

0

Small-scale

0.709

High

1325006

ASCC3
Activating signal cointegrator 1 complex subunit 3

6

0

Small-scale

0.706

High

1151386

TRIP4
Activating signal cointegrator 1

6

0

Small-scale

0.697

High

856914

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.656

High

1400599

ALKB3
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3

3

0

High-throughput

0.638

High

1406152

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.580

High

658400

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.576

High

860940

RS10
Small ribosomal subunit protein eS10

2

0

High-throughput

0.576

High

396921

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

401468

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

1

High-throughput

0.571

High

1058646

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.541

High

74599

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

1

High-throughput

0.536

High

1431119

DRG1
Developmentally-regulated GTP-binding protein 1

1

1

High-throughput

0.536

High

320409

SASH1
SAM and SH3 domain-containing protein 1

1

0

Small-scale

0.529

High

246939

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.518

High

280429

DEAF1
Deformed epidermal autoregulatory factor 1 homolog

1

0

High-throughput

0.518

High

369088

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.518

High

428226

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.518

High

482544

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.518

High

574467

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.518

High

665283

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.518

High

696472

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.518

High

714964

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.518

High

773014

MYH9
Myosin-9

1

0

High-throughput

0.518

High

1085829

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.518

High

1122771

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.518

High

1410036

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.518

High

1413580

URM1
Ubiquitin-related modifier 1

1

0

High-throughput

0.518

High

1415536

GNL3
Guanine nucleotide-binding protein-like 3

1

0

High-throughput

0.518

High

1416211

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.518

High

1431108

CUTC
Copper homeostasis protein cutC homolog

1

0

High-throughput

0.518

High

1431116

FAF1
FAS-associated factor 1

1

0

High-throughput

0.518

High

1431118

PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

1

0

High-throughput

0.518

High

1431120

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.518

High

1431123

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.518

High

447427

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

502529

H2A1
Histone H2A type 1

1

0

High-throughput

0.513

High

973299

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

973583

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

979226

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.513

High

992955

RACK1
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.513

High

1110067

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.513

High

1111434

DGKZ
Diacylglycerol kinase zeta

1

0

High-throughput

0.513

High

1310395

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1334222

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.513

High

1370628

GPKOW
G-patch domain and KOW motifs-containing protein

1

0

High-throughput

0.513

High

1383851

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1387888

PABP5
Polyadenylate-binding protein 5

1

0

High-throughput

0.513

High

1409837

RBM4B
RNA-binding protein 4B

1

0

High-throughput

0.513

High

1417874

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

1431114

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

1431115

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

1431107

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.494

High

1313596

DDX60
Probable ATP-dependent RNA helicase DDX60

1

1

High-throughput

0.489

High

1431122

RNF11
RING finger protein 11

1

0

High-throughput

0.486

High

1111260

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.481

High

1431104

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

Small-scale

0.480

High

504972

H2AB2
Histone H2A-Bbd type 2/3

1

1

High-throughput

0.479

High

1047104

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

1

Small-scale

0.479

High

1367243

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

279491

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

316003

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

637155

CSRP1
Cysteine and glycine-rich protein 1

1

0

Small-scale

0.458

High

684387

DDX6
Probable ATP-dependent RNA helicase DDX6

1

0

High-throughput

0.458

High

831408

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

954267

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

1024837

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1088561

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.458

High

1092239

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

1106701

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1125225

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

0

High-throughput

0.458

High

1329865

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1330928

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1338365

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1393683

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1412092

TRI56
E3 ubiquitin-protein ligase TRIM56

1

0

High-throughput

0.458

High

1431105

BRD7
Bromodomain-containing protein 7

1

0

High-throughput

0.458

High

1431106

ANLN
Anillin

1

0

High-throughput

0.458

High

1431109

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1431113

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.458

High

1395005

RADIL
Ras-associating and dilute domain-containing protein

1

1

High-throughput

0.439

High

1255490

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1256587

CE128
Centrosomal protein of 128 kDa

1

1

High-throughput

0.437

High

1336631

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.437

High

1429457

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

1

High-throughput

0.437

High

1431102

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

809841

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.426

High

959958

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.426

High

969434

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.426

High

1056966

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.426

High

1157683

CRY1
Cryptochrome-1

1

0

Small-scale

0.426

High

1431121

RRP7A
Ribosomal RNA-processing protein 7 homolog A

1

0

High-throughput

0.426

High

1233187

Q6I9S2
SNW domain-containing protein 1

1

1

High-throughput

0.417

High

1260279

Q75LH2
Ras-associating and dilute domain-containing protein

1

1

High-throughput

0.417

High

109159

G4U4J3
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.407

High

259097

DNJA2
DnaJ homolog subfamily A member 2

2

0

High-throughput

0.318

High

1415927

KATL1
Katanin p60 ATPase-containing subunit A-like 1

2

0

High-throughput

0.316

High

132799

PK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

1

0

High-throughput

0.282

High

449538

LIPL
Lipoprotein lipase

1

0

High-throughput

0.282

High

938674

ALR
FAD-linked sulfhydryl oxidase ALR

1

0

High-throughput

0.282

High

1164560

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.282

High

1339845

PJA1
E3 ubiquitin-protein ligase Praja-1

1

0

High-throughput

0.282

High

1430242

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

0

High-throughput

0.282

High

1431103

TBC17
TBC1 domain family member 17

1

0

High-throughput

0.282

High

1431110

TUTLA
Protein turtle homolog A

1

0

High-throughput

0.282

High

161837

RIOK3
Serine/threonine-protein kinase RIO3

1

0

High-throughput

0.279

Low

613457

VINC
Vinculin

1

0

High-throughput

0.279

Low

1022470

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1099637

NOGG
Noggin

1

0

High-throughput

0.279

Low

1136360

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.279

Low

1398709

AP4AT
AP-4 complex accessory subunit Tepsin

1

0

High-throughput

0.279

Low

1409593

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.279

Low

1431112

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.279

Low

1098842

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

0

Small-scale

0.261

Low

124964

GTPB1
GTP-binding protein 1

1

0

High-throughput

0.249

Low

346312

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

412587

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1295552

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.249

Low

1327189

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1431111

C2D2A
Coiled-coil and C2 domain-containing protein 2A

1

0

High-throughput

0.249

Low

1431117

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.249

Low

1155187

EREP1
Endosomal transmembrane epsin interactor 1

1

0

Small-scale

0.238

Low

288199

CLC3A
C-type lectin domain family 3 member A

1

0

High-throughput

0.232

Low

517262

AMY1B
Alpha-amylase 1B

1

0

High-throughput

0.232

Low

1227434

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025