Protein: SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (U4/U6.U5 snRNP 27 kDa protein) (U4/U6.U5-27K) (Nucleic acid-binding protein RY-1) (U4/U6.U5 tri-snRNP-associated 27 kDa protein) (27K) (U4/U6.U5 tri-snRNP-associated protein 3)

Gene: SNR27, SNRNP27
Organism: Homo sapiens
Interactions: 165
UniProt ID: Q8WVK2

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003676 - nucleic acid binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0046540 - U4/U6 x U5 tri-snRNP complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

942835

SRPK2
SRSF protein kinase 2

4

1

High-throughput

0.708

High

1261477

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

3

1

High-throughput

0.667

High

959566

VIGLN
Vigilin

3

0

High-throughput

0.638

High

647637

MK03
Mitogen-activated protein kinase 3

2

1

High-throughput

0.628

High

1026932

PAK2
Serine/threonine-protein kinase PAK 2

2

2

High-throughput

0.628

High

1261483

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

1

High-throughput

0.628

High

1261498

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

1

High-throughput

0.628

High

1261512

SNX6
Sorting nexin-6

2

1

High-throughput

0.628

High

1261479

OTUB1
Ubiquitin thioesterase OTUB1

3

0

High-throughput

0.622

High

912081

RUXG
Small nuclear ribonucleoprotein G

2

3

High-throughput

0.611

High

48124

UBA6
Ubiquitin-like modifier-activating enzyme 6

2

0

High-throughput

0.602

High

202494

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

2

0

High-throughput

0.602

High

213851

SYNC
Asparagine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.602

High

664251

TPP2
Tripeptidyl-peptidase 2

2

0

High-throughput

0.602

High

670798

BLVRB
Flavin reductase

2

0

High-throughput

0.602

High

764401

FEN1
Flap endonuclease 1

2

0

High-throughput

0.602

High

801921

RECQ1
ATP-dependent DNA helicase Q1

2

0

High-throughput

0.602

High

911699

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.602

High

927989

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

0

High-throughput

0.602

High

948821

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

2

0

High-throughput

0.602

High

985999

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

0

High-throughput

0.602

High

1021767

PP1R8
Nuclear inhibitor of protein phosphatase 1

2

0

High-throughput

0.602

High

1036450

PICAL
Phosphatidylinositol-binding clathrin assembly protein

2

0

High-throughput

0.602

High

1038009

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

0

High-throughput

0.602

High

1078479

TOM34
Mitochondrial import receptor subunit TOM34

2

0

High-throughput

0.602

High

1102935

QRIC1
Transcriptional regulator QRICH1

2

0

High-throughput

0.602

High

1153039

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

2

0

High-throughput

0.602

High

1261469

CTBL1
Beta-catenin-like protein 1

2

0

High-throughput

0.602

High

1261473

SYAP1
Synapse-associated protein 1

2

0

High-throughput

0.602

High

1261480

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

2

0

High-throughput

0.602

High

1261481

CAR19
Caspase recruitment domain-containing protein 19

2

0

High-throughput

0.602

High

1261484

QKI
KH domain-containing RNA-binding protein QKI

2

0

High-throughput

0.602

High

1261485

S10AD
Protein S100-A13

2

0

High-throughput

0.602

High

1261487

VRK1
Serine/threonine-protein kinase VRK1

2

0

High-throughput

0.602

High

1261491

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

2

0

High-throughput

0.602

High

1261493

NAA50
N-alpha-acetyltransferase 50

2

0

High-throughput

0.602

High

1261494

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

2

0

High-throughput

0.602

High

1261496

ARMT1
Damage-control phosphatase ARMT1

2

0

High-throughput

0.602

High

1261497

UBE2T
Ubiquitin-conjugating enzyme E2 T

2

0

High-throughput

0.602

High

1261499

RBM12
RNA-binding protein 12

2

0

High-throughput

0.602

High

1261513

RRP44
Exosome complex exonuclease RRP44

2

0

High-throughput

0.602

High

1261515

SBDS
Ribosome maturation protein SBDS

2

0

High-throughput

0.602

High

234974

SNX3
Sorting nexin-3

2

1

High-throughput

0.574

High

240775

USO1
General vesicular transport factor p115

2

1

High-throughput

0.574

High

277613

PAK3
Serine/threonine-protein kinase PAK 3

2

2

High-throughput

0.574

High

300787

GLSK
Glutaminase kidney isoform, mitochondrial

2

1

High-throughput

0.574

High

320551

OXSR1
Serine/threonine-protein kinase OSR1

2

1

High-throughput

0.574

High

950669

ARF5
ADP-ribosylation factor 5

2

1

High-throughput

0.574

High

1202773

WDR5B
WD repeat-containing protein 5B

2

2

High-throughput

0.574

High

1261492

EIF2A
Eukaryotic translation initiation factor 2A

2

1

High-throughput

0.574

High

1261495

SLK
STE20-like serine/threonine-protein kinase

2

2

High-throughput

0.574

High

1261500

TXLNG
Gamma-taxilin

2

1

High-throughput

0.574

High

1261503

STK26
Serine/threonine-protein kinase 26

2

2

High-throughput

0.574

High

1261522

SAR1B
Small COPII coat GTPase SAR1B

2

2

High-throughput

0.574

High

1219711

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

1

High-throughput

0.573

High

659010

MK01
Mitogen-activated protein kinase 1

1

1

High-throughput

0.536

High

1261507

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

3

High-throughput

0.536

High

1261517

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

4

High-throughput

0.536

High

197060

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

2

High-throughput

0.515

High

204004

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

453875

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

High-throughput

0.513

High

455696

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.513

High

537970

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.513

High

722625

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.513

High

834499

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

0

High-throughput

0.513

High

846572

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.513

High

887589

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

895207

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.513

High

928149

SUMO1
Small ubiquitin-related modifier 1

1

0

High-throughput

0.513

High

951883

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.513

High

958488

CYC
Cytochrome c

1

0

High-throughput

0.513

High

961557

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

0

High-throughput

0.513

High

1012504

HSP7E
Heat shock 70 kDa protein 14

1

0

High-throughput

0.513

High

1015815

SCRN1
Secernin-1

1

0

High-throughput

0.513

High

1045642

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.513

High

1059758

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.513

High

1063349

CND1
Condensin complex subunit 1

1

0

High-throughput

0.513

High

1068221

PEA15
Astrocytic phosphoprotein PEA-15

1

0

High-throughput

0.513

High

1074190

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1080735

ZYX
Zyxin

1

0

High-throughput

0.513

High

1109566

TKFC
Triokinase/FMN cyclase

1

0

High-throughput

0.513

High

1183335

DDX46
Probable ATP-dependent RNA helicase DDX46

1

0

High-throughput

0.513

High

1190690

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.513

High

1244632

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.513

High

1259850

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

0

High-throughput

0.513

High

1261470

PSMF1
Proteasome inhibitor PI31 subunit

1

0

High-throughput

0.513

High

1261472

EZH1
Histone-lysine N-methyltransferase EZH1

1

0

High-throughput

0.513

High

1261486

KIF2C
Kinesin-like protein KIF2C

1

0

High-throughput

0.513

High

1261488

RBM42
RNA-binding protein 42

1

0

High-throughput

0.513

High

1261489

H2AJ
Histone H2A.J

1

0

High-throughput

0.513

High

1261504

CGBP1
CGG triplet repeat-binding protein 1

1

0

High-throughput

0.513

High

1261511

TPX2
Targeting protein for Xklp2

1

0

High-throughput

0.513

High

1261518

PPME1
Protein phosphatase methylesterase 1

1

0

High-throughput

0.513

High

1121176

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

0

High-throughput

0.493

High

770650

TXLNA
Alpha-taxilin

1

2

High-throughput

0.489

High

913018

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.489

High

1067450

EEA1
Early endosome antigen 1

1

1

High-throughput

0.489

High

269257

WBP4
WW domain-binding protein 4

1

1

High-throughput

0.481

High

347434

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

379653

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

833937

CLK2
Dual specificity protein kinase CLK2

1

0

High-throughput

0.460

High

304263

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.458

High

313323

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.458

High

319944

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

374599

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

908878

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

917654

H4
Histone H4

1

0

High-throughput

0.458

High

1045342

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

1085853

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1184229

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1201563

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1234219

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

Small-scale

0.458

High

1235573

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

1261471

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1261505

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1261519

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

0

Small-scale

0.458

High

68439

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

3

High-throughput

0.445

High

348827

RASN
GTPase NRas

1

1

High-throughput

0.437

High

1261510

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

199057

PAPS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

2

0

High-throughput

0.328

High

207733

DENR
Density-regulated protein

2

0

High-throughput

0.328

High

307403

LETM1
Mitochondrial proton/calcium exchanger protein

2

0

High-throughput

0.328

High

335483

NB5R3
NADH-cytochrome b5 reductase 3

2

0

High-throughput

0.328

High

646430

KAD4
Adenylate kinase 4, mitochondrial

2

0

High-throughput

0.328

High

914552

ERF1
Eukaryotic peptide chain release factor subunit 1

2

0

High-throughput

0.328

High

984403

EF1A2
Elongation factor 1-alpha 2

2

0

High-throughput

0.328

High

1047782

CKAP5
Cytoskeleton-associated protein 5

2

0

High-throughput

0.328

High

1056381

PLSI
Plastin-1

2

0

High-throughput

0.328

High

1060020

LASP1
LIM and SH3 domain protein 1

2

0

High-throughput

0.328

High

1068409

PMVK
Phosphomevalonate kinase

2

0

High-throughput

0.328

High

1079389

VAMP3
Vesicle-associated membrane protein 3

2

0

High-throughput

0.328

High

1126166

MTX3
Metaxin-3

2

0

High-throughput

0.328

High

1261478

MITOK
Mitochondrial potassium channel

2

0

High-throughput

0.328

High

1261490

PDC10
Programmed cell death protein 10

2

0

High-throughput

0.328

High

1261506

CHRD1
Cysteine and histidine-rich domain-containing protein 1

2

0

High-throughput

0.328

High

1261516

TLN1
Talin-1

2

0

High-throughput

0.328

High

1261514

LC7L2
Putative RNA-binding protein Luc7-like 2

2

0

High-throughput

0.318

High

150071

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.279

Low

153936

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

0

High-throughput

0.279

Low

159668

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

225893

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

0

High-throughput

0.279

Low

456179

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

650130

CO8A1
Collagen alpha-1(VIII) chain

1

0

High-throughput

0.279

Low

674961

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.279

Low

1045089

LAMB3
Laminin subunit beta-3

1

0

High-throughput

0.279

Low

1075064

MARE2
Microtubule-associated protein RP/EB family member 2

1

0

High-throughput

0.279

Low

1086680

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.279

Low

1138414

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

1231396

CT197
Putative uncharacterized protein encoded by LINC02910

1

0

High-throughput

0.279

Low

1245525

ATLA2
Atlastin-2

1

0

High-throughput

0.279

Low

1261468

JPH3
Junctophilin-3

1

0

High-throughput

0.279

Low

1261474

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1261475

EFHD2
EF-hand domain-containing protein D2

1

0

High-throughput

0.279

Low

1261482

PRRC1
Protein PRRC1

1

0

High-throughput

0.279

Low

1261502

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

1261508

MCTS1
Malignant T-cell-amplified sequence 1

1

0

High-throughput

0.279

Low

1261509

ANR50
Ankyrin repeat domain-containing protein 50

1

0

High-throughput

0.279

Low

1261520

TNPO3
Transportin-3

1

0

High-throughput

0.279

Low

1261521

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

1261523

S23IP
SEC23-interacting protein

1

0

High-throughput

0.279

Low

149101

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

1261476

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.249

Low

1261501

TBA8
Tubulin alpha-8 chain

1

0

High-throughput

0.249

Low

891242

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.232

Low

995559

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024