Protein: LIAS
Lipoyl synthase, mitochondrial (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoic acid synthase)

Gene: LIAS
Organism: Homo sapiens
Interactions: 23
UniProt ID: O43766

Gene Ontology (top 5):
GO:0001843 - neural tube closure
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006954 - inflammatory response
GO:0006979 - response to oxidative stress

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

226935

GCSH
Glycine cleavage system H protein, mitochondrial

2

1

High-throughput

0.601

High

226936

CASPE
Caspase-14

1

0

High-throughput

0.513

High

226940

NDUF5
Arginine-hydroxylase NDUFAF5, mitochondrial

1

0

High-throughput

0.513

High

226944

DPOG2
DNA polymerase subunit gamma-2

1

0

High-throughput

0.513

High

226925

CATL2
Cathepsin L2

1

1

High-throughput

0.489

High

226927

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

226933

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

226929

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

1

High-throughput

0.445

High

226945

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

1

1

High-throughput

0.445

High

223770

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.426

High

226938

DPOE1
DNA polymerase epsilon catalytic subunit A

1

0

High-throughput

0.426

High

226939

H90B4
Putative heat shock protein HSP 90-beta 4

1

1

High-throughput

0.407

High

226931

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.282

High

226926

INVO
Involucrin

1

0

High-throughput

0.279

Low

226934

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

226937

AL1A3
Retinaldehyde dehydrogenase 3

1

0

High-throughput

0.279

Low

226942

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

226943

TREX2
Three prime repair exonuclease 2

1

0

High-throughput

0.279

Low

226930

LYL1
Protein lyl-1

1

0

High-throughput

0.249

Low

226932

AMPN
Aminopeptidase N

1

0

High-throughput

0.249

Low

226941

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low

137397

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

0

High-throughput

0.232

Low

226928

H14
Histone H1.4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025