Protein: TREX2
Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2)

Gene: TREX2
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q9BQ50

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006259 - DNA metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

391656

FRIH
Ferritin heavy chain

2

0

High-throughput

0.602

High

1400514

CDK15
Cyclin-dependent kinase 15

2

0

High-throughput

0.602

High

1410009

DD19B
ATP-dependent RNA helicase DDX19B

2

0

High-throughput

0.585

High

445058

S10A9
Protein S100-A9

1

2

High-throughput

0.536

High

713439

SPB3
Serpin B3

1

2

High-throughput

0.536

High

724625

S10A7
Protein S100-A7

1

2

High-throughput

0.536

High

787700

SPB5
Serpin B5

1

2

High-throughput

0.536

High

1286350

S1A7A
Protein S100-A7A

1

2

High-throughput

0.536

High

248767

PEPL
Periplakin

1

0

High-throughput

0.513

High

552366

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.513

High

568974

ANXA8
Annexin A8

1

0

High-throughput

0.513

High

582614

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.513

High

600566

ZSC20
Zinc finger and SCAN domain-containing protein 20

1

0

High-throughput

0.513

High

602831

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

627155

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.513

High

711737

RABP2
Cellular retinoic acid-binding protein 2

1

0

High-throughput

0.513

High

733425

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

818765

CAPG
Macrophage-capping protein

1

0

High-throughput

0.513

High

1010774

SSBP2
Single-stranded DNA-binding protein 2

1

0

High-throughput

0.513

High

1271213

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.513

High

1292336

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.513

High

1306982

CERS3
Ceramide synthase 3

1

0

High-throughput

0.513

High

1308693

FMNL3
Formin-like protein 3

1

0

High-throughput

0.513

High

1316240

DOCK3
Dedicator of cytokinesis protein 3

1

0

High-throughput

0.513

High

1410003

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

1410004

KLH11
Kelch-like protein 11

1

0

High-throughput

0.513

High

1410005

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.513

High

1410008

PHF11
PHD finger protein 11

1

0

High-throughput

0.513

High

1410010

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

874852

SPB4
Serpin B4

1

2

High-throughput

0.489

High

957827

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

Small-scale

0.480

High

1410007

DUX4
Double homeobox protein 4

1

1

High-throughput

0.479

High

617243

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

0

High-throughput

0.460

High

872679

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

1410002

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

75714

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

1408317

PKP2
Plakophilin-2

1

0

High-throughput

0.426

High

69540

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

1330632

CCYL1
Cyclin-Y-like protein 1

2

0

High-throughput

0.328

High

1410011

FCF1
rRNA-processing protein FCF1 homolog

2

0

High-throughput

0.328

High

1131221

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

226943

LIAS
Lipoyl synthase, mitochondrial

1

0

High-throughput

0.279

Low

255189

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.279

Low

325352

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

609328

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.279

Low

943120

STX17
Syntaxin-17

1

0

High-throughput

0.279

Low

1009709

NGAL
Neutrophil gelatinase-associated lipocalin

1

0

High-throughput

0.279

Low

1023869

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.279

Low

1292223

BPHL
Serine hydrolase BPHL

1

0

High-throughput

0.279

Low

1353342

PAR3L
Partitioning defective 3 homolog B

1

0

High-throughput

0.279

Low

1380525

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.279

Low

1408221

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

1410001

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

1410006

SELN
Selenoprotein N

1

0

High-throughput

0.279

Low

261262

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025