Protein: TYPH
Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase)

Gene: TYPH, TYMP
Organism: Homo sapiens
Interactions: 91
UniProt ID: P19971

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0004645 - 1,4-alpha-oligoglucan phosphorylase activity
GO:0005829 - cytosol
GO:0006206 - pyrimidine nucleobase metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

627106

TYPH
Thymidine phosphorylase

1

1

High-throughput

0.698

High

627160

RBM24
RNA-binding protein 24

3

0

High-throughput

0.638

High

627151

CDK15
Cyclin-dependent kinase 15

2

0

High-throughput

0.602

High

410610

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

0

High-throughput

0.551

High

602729

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

627107

PO3F3
POU domain, class 3, transcription factor 3

1

0

High-throughput

0.513

High

627112

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

627115

PCP4
Calmodulin regulator protein PCP4

1

0

High-throughput

0.513

High

627119

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

627121

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.513

High

627123

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

627124

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

0

High-throughput

0.513

High

627125

GABPA
GA-binding protein alpha chain

1

0

High-throughput

0.513

High

627130

SYT6
Synaptotagmin-6

1

0

High-throughput

0.513

High

627155

TREX2
Three prime repair exonuclease 2

1

0

High-throughput

0.513

High

627161

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

627166

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

627170

KLH11
Kelch-like protein 11

1

0

High-throughput

0.513

High

627177

CHMP3
Charged multivesicular body protein 3

1

0

High-throughput

0.513

High

627179

RN115
E3 ubiquitin-protein ligase RNF115

1

0

High-throughput

0.513

High

552121

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.489

High

627180

RPKL1
Ribosomal protein S6 kinase-like 1

1

1

High-throughput

0.489

High

240726

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

461139

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

627110

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.458

High

627114

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

627141

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

627163

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

627113

PI4KA
Phosphatidylinositol 4-kinase alpha

1

2

High-throughput

0.445

High

627129

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

2

High-throughput

0.437

High

627108

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

0

High-throughput

0.426

High

627132

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

627147

ASB9
Ankyrin repeat and SOCS box protein 9

1

0

High-throughput

0.426

High

627164

CARD9
Caspase recruitment domain-containing protein 9

1

0

High-throughput

0.426

High

627140

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

2

High-throughput

0.407

High

627173

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

1

High-throughput

0.407

High

600535

ZSC20
Zinc finger and SCAN domain-containing protein 20

3

0

High-throughput

0.347

High

627148

GMCL1
Germ cell-less protein-like 1

3

0

High-throughput

0.347

High

627149

SUSD3
Sushi domain-containing protein 3

3

0

High-throughput

0.347

High

627158

YJU2
Splicing factor YJU2

3

0

High-throughput

0.347

High

627135

KHDC4
KH homology domain-containing protein 4

2

0

High-throughput

0.328

High

627165

SHCAF
SIN3-HDAC complex-associated factor

2

0

High-throughput

0.328

High

627169

TB22B
TBC1 domain family member 22B

2

0

High-throughput

0.328

High

627171

GPT2L
G patch domain-containing protein 2-like

2

0

High-throughput

0.328

High

627131

MYOME
Myomegalin

2

0

High-throughput

0.318

High

627174

DD19B
ATP-dependent RNA helicase DDX19B

2

0

High-throughput

0.318

High

627127

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

627162

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

132564

UPK1A
Uroplakin-1a

1

0

High-throughput

0.279

Low

226934

LIAS
Lipoyl synthase, mitochondrial

1

0

High-throughput

0.279

Low

229212

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

0

High-throughput

0.279

Low

254797

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.279

Low

292545

RENR
Renin receptor

1

0

High-throughput

0.279

Low

325279

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

351658

SG1D1
Secretoglobin family 1D member 1

1

0

High-throughput

0.279

Low

622747

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

0

High-throughput

0.279

Low

627109

CCNC
Cyclin-C

1

0

High-throughput

0.279

Low

627111

EPHA8
Ephrin type-A receptor 8

1

0

High-throughput

0.279

Low

627116

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

627117

ASCL1
Achaete-scute homolog 1

1

0

High-throughput

0.279

Low

627120

DSCR6
Protein ripply3

1

0

High-throughput

0.279

Low

627122

SSBP2
Single-stranded DNA-binding protein 2

1

0

High-throughput

0.279

Low

627126

ZN154
Zinc finger protein 154

1

0

High-throughput

0.279

Low

627128

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

627134

APTX
Aprataxin

1

0

High-throughput

0.279

Low

627136

COA5
Cytochrome c oxidase assembly factor 5

1

0

High-throughput

0.279

Low

627137

CERS3
Ceramide synthase 3

1

0

High-throughput

0.279

Low

627138

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

627139

AN36B
Ankyrin repeat domain-containing protein 36B

1

0

High-throughput

0.279

Low

627142

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

627143

ZDH19
Palmitoyltransferase ZDHHC19

1

0

High-throughput

0.279

Low

627144

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.279

Low

627145

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.279

Low

627146

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

627150

F227B
Protein FAM227B

1

0

High-throughput

0.279

Low

627152

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

627154

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

627156

SH23A
SH2 domain-containing protein 3A

1

0

High-throughput

0.279

Low

627157

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

627159

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.279

Low

627167

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.279

Low

627172

PHF11
PHD finger protein 11

1

0

High-throughput

0.279

Low

627176

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

627168

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.249

Low

627178

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.249

Low

261081

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

627118

GPC3
Glypican-3

1

0

High-throughput

0.232

Low

627133

RL7L
Ribosomal protein uL30-like

1

0

High-throughput

0.232

Low

627153

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.232

Low

627175

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025