Protein: NDUB4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (Complex I-B15) (CI-B15) (NADH-ubiquinone oxidoreductase B15 subunit)

Gene: NDUB4, NDUFB4
Organism: Homo sapiens
Interactions: 69
UniProt ID: O95168

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006120 - mitochondrial electron transport, NADH to ubiquinone
GO:0008137 - NADH dehydrogenase (ubiquinone) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

283745

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

4

0

High-throughput

0.664

High

231184

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

2

0

High-throughput

0.602

High

278594

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

2

0

High-throughput

0.602

High

328306

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

2

0

High-throughput

0.602

High

328329

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

2

0

High-throughput

0.602

High

328299

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

2

0

High-throughput

0.585

High

328291

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

2

0

High-throughput

0.576

High

328288

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

328295

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

2

0

High-throughput

0.559

High

183800

NDUA1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1

1

0

High-throughput

0.513

High

209720

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

1

0

High-throughput

0.513

High

223683

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

0

High-throughput

0.513

High

328281

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

1

0

High-throughput

0.513

High

328282

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.513

High

328289

NEP
Neprilysin

1

0

Small-scale

0.513

High

328297

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.513

High

328298

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.513

High

328301

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

0

High-throughput

0.513

High

328312

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

0

High-throughput

0.513

High

328313

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

328322

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.513

High

328328

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

328333

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.513

High

328320

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

137595

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

169867

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

240356

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

314977

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

328283

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

328286

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

328290

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.458

High

328293

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

328294

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

328300

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

328314

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

328315

SNIP1
Smad nuclear-interacting protein 1

1

0

Small-scale

0.458

High

328323

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

328324

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

328327

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

328331

QCR9
Cytochrome b-c1 complex subunit 9

1

0

High-throughput

0.458

High

328332

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

328304

S35B1
Solute carrier family 35 member B1

1

1

High-throughput

0.445

High

328321

SNX27
Sorting nexin-27

1

3

High-throughput

0.437

High

328325

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

328302

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

0

Small-scale

0.426

High

328307

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

328303

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

328317

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.407

High

328310

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

2

0

High-throughput

0.318

High

165878

FFAR1
Free fatty acid receptor 1

1

0

High-throughput

0.279

Low

328287

FRIL
Ferritin light chain

1

0

High-throughput

0.279

Low

328292

FUT1
Galactoside alpha-(1,2)-fucosyltransferase 1

1

0

High-throughput

0.279

Low

328309

SCAR3
Scavenger receptor class A member 3

1

0

High-throughput

0.279

Low

328319

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

0

High-throughput

0.279

Low

328330

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.279

Low

328336

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

164202

NRP1
Neuropilin-1

1

0

High-throughput

0.249

Low

292974

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

328284

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

328296

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.249

Low

328308

FTM
Protein fantom

1

0

High-throughput

0.249

Low

328311

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

328316

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.249

Low

328318

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

328326

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

328285

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

0

High-throughput

0.232

Low

328305

MFS10
Major facilitator superfamily domain-containing protein 10

1

0

High-throughput

0.232

Low

328334

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low

328335

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025