Protein: NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (Complex I-PGIV) (CI-PGIV) (NADH-ubiquinone oxidoreductase 19 kDa subunit)

Gene: NDUA8, NDUFA8
Organism: Homo sapiens
Interactions: 129
UniProt ID: P51970

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0006120 - mitochondrial electron transport, NADH to ubiquinone
GO:0008137 - NADH dehydrogenase (ubiquinone) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

909492

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

4

0

High-throughput

0.836

High

183814

NDUA1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1

3

0

High-throughput

0.816

High

397593

NU1M
NADH-ubiquinone oxidoreductase chain 1

3

0

High-throughput

0.816

High

223610

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

3

1

High-throughput

0.667

High

333565

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

3

1

High-throughput

0.667

High

397676

NU4M
NADH-ubiquinone oxidoreductase chain 4

3

1

High-throughput

0.667

High

397732

NU5M
NADH-ubiquinone oxidoreductase chain 5

3

1

High-throughput

0.667

High

622138

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

4

0

High-throughput

0.661

High

909437

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

4

0

High-throughput

0.661

High

348431

AIFM1
Apoptosis-inducing factor 1, mitochondrial

3

1

High-throughput

0.643

High

127470

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

3

0

High-throughput

0.638

High

209757

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

3

0

High-throughput

0.638

High

223716

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

3

0

High-throughput

0.638

High

278639

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

3

0

High-throughput

0.638

High

281817

NDUB1
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

3

0

High-throughput

0.638

High

326468

NDUB6
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6

3

0

High-throughput

0.638

High

328234

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

3

0

High-throughput

0.638

High

328365

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

3

0

High-throughput

0.638

High

328518

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

3

0

High-throughput

0.638

High

605444

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

3

0

High-throughput

0.638

High

702553

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

3

0

High-throughput

0.638

High

890933

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

3

0

High-throughput

0.638

High

909422

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

3

0

High-throughput

0.638

High

909471

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

3

0

High-throughput

0.638

High

909494

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

3

0

High-throughput

0.638

High

909496

CIA30
Complex I intermediate-associated protein 30, mitochondrial

3

0

High-throughput

0.638

High

909498

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

3

0

High-throughput

0.638

High

371520

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.611

High

909432

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

3

2

High-throughput

0.609

High

909433

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

3

2

High-throughput

0.609

High

275269

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

2

0

High-throughput

0.585

High

275635

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

2

0

High-throughput

0.585

High

328299

NDUB4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

2

0

High-throughput

0.585

High

909483

ACAD9
Complex I assembly factor ACAD9, mitochondrial

2

0

High-throughput

0.585

High

909454

JOS2
Josephin-2

2

2

High-throughput

0.574

High

283828

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

2

0

Small-scale

0.559

High

559912

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.559

High

909484

SFXN1
Sideroflexin-1

2

0

High-throughput

0.559

High

395727

ESR1
Estrogen receptor

2

1

High-throughput

0.521

High

529384

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

901138

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.513

High

909430

ATM
Serine-protein kinase ATM

1

0

High-throughput

0.513

High

909441

KLC3
Kinesin light chain 3

1

0

High-throughput

0.513

High

909449

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

0

High-throughput

0.513

High

909472

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

1

0

High-throughput

0.513

High

909486

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

909474

TRI55
Tripartite motif-containing protein 55

1

2

High-throughput

0.494

High

292100

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

1

High-throughput

0.479

High

909467

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

909468

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

909478

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

2

High-throughput

0.479

High

109385

G5E9A7
DM1 locus, WD repeat containing

1

1

High-throughput

0.470

High

909447

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.470

High

137681

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

216647

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.458

High

223812

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.458

High

231220

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.458

High

245446

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.458

High

274994

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

296215

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

505422

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

532470

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

909427

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

909431

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

909436

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

909445

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

909448

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

909456

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.458

High

909457

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

1

0

High-throughput

0.458

High

909459

FXRD1
FAD-dependent oxidoreductase domain-containing protein 1

1

0

Small-scale

0.458

High

909461

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

909463

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.458

High

909464

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

909469

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.458

High

909470

PHB2
Prohibitin-2

1

0

High-throughput

0.458

High

909473

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

909475

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

909476

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

909477

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.458

High

909479

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

909485

PLRKT
Plasminogen receptor

1

0

High-throughput

0.458

High

909487

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

909490

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.458

High

909491

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

909458

TRI63
E3 ubiquitin-protein ligase TRIM63

1

2

High-throughput

0.439

High

405923

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

789448

PPARG
Peroxisome proliferator-activated receptor gamma

1

1

High-throughput

0.437

High

909421

ATX3
Ataxin-3

1

2

Small-scale

0.437

High

909434

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

2

High-throughput

0.437

High

909443

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

909444

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.437

High

909450

ASXL1
Polycomb group protein ASXL1

1

1

High-throughput

0.437

High

909462

RNF31
E3 ubiquitin-protein ligase RNF31

1

1

Small-scale

0.437

High

909480

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

909493

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

909423

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

0

Small-scale

0.426

High

909465

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.426

High

909424

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

909446

WAPL
Wings apart-like protein homolog

3

0

High-throughput

0.347

High

866918

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

909428

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

0

High-throughput

0.279

Low

909429

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.279

Low

909452

CNTRB
Centrobin

1

0

High-throughput

0.279

Low

909497

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

909438

GRPL2
GLIPR1-like protein 2

1

0

High-throughput

0.269

Low

246492

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.251

Low

293399

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

377468

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

536793

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

606466

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

674970

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.249

Low

830382

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

909425

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.249

Low

909426

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

909435

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.249

Low

909439

MIDN
Midnolin

1

0

High-throughput

0.249

Low

909442

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

909451

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.249

Low

909455

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

909460

OPTN
Optineurin

1

0

High-throughput

0.249

Low

909466

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

909481

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

909482

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

909488

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

909489

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

247096

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.238

Low

909440

S39AC
Zinc transporter ZIP12

1

0

High-throughput

0.232

Low

909453

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

909495

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025