Protein: ABRX1
BRCA1-A complex subunit Abraxas 1 (Coiled-coil domain-containing protein 98) (Protein FAM175A)

Gene: ABRX1, ABRAXAS1
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q6UWZ7

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006282 - regulation of DNA repair
GO:0006302 - double-strand break repair
GO:0006325 - chromatin organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

858782

BRCC3
Lys-63-specific deubiquitinase BRCC36

11

3

Small-scale

0.979

High

1248951

BABA2
BRISC and BRCA1-A complex member 2

7

1

Small-scale

0.963

High

1248946

UIMC1
BRCA1-A complex subunit RAP80

21

1

Small-scale

0.767

High

799225

BRCA1
Breast cancer type 1 susceptibility protein

16

1

Small-scale

0.764

High

1248950

BABA1
BRISC and BRCA1-A complex member 1

13

1

Small-scale

0.760

High

508158

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

5

3

Small-scale

0.710

High

1136452

FL2D
Pre-mRNA-splicing regulator WTAP

3

1

High-throughput

0.667

High

1248948

BARD1
BRCA1-associated RING domain protein 1

3

2

Small-scale

0.640

High

1248943

TEKT4
Tektin-4

3

0

High-throughput

0.638

High

968961

PRS8
26S proteasome regulatory subunit 8

2

4

High-throughput

0.628

High

535855

LAMC1
Laminin subunit gamma-1

3

1

High-throughput

0.609

High

1036110

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

2

0

High-throughput

0.602

High

964337

SUMO2
Small ubiquitin-related modifier 2

2

0

Small-scale

0.598

High

1129630

MDC1
Mediator of DNA damage checkpoint protein 1

2

2

High-throughput

0.584

High

1123571

ZMYM3
Zinc finger MYM-type protein 3

1

0

High-throughput

0.537

High

563945

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

185789

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

936193

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

High-throughput

0.493

High

142571

IMA3
Importin subunit alpha-3

1

0

High-throughput

0.480

High

728299

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.480

High

1088881

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1115744

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.479

High

1248942

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.479

High

1248952

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

185203

FANCG
Fanconi anemia group G protein

1

0

Small-scale

0.458

High

487450

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.458

High

761721

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

786680

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.458

High

979861

H4
Histone H4

1

0

High-throughput

0.458

High

1016965

H33
Histone H3.3

1

0

High-throughput

0.458

High

1045423

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1113461

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1248941

ABRX1
BRCA1-A complex subunit Abraxas 1

1

0

Small-scale

0.458

High

1248944

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1248947

CTIP
DNA endonuclease RBBP8

1

0

Small-scale

0.458

High

1248949

FANCJ
Fanconi anemia group J protein

1

0

Small-scale

0.426

High

921543

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

0

High-throughput

0.347

High

1248953

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

1

0

High-throughput

0.279

Low

1248945

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025