Protein: UIMC1
BRCA1-A complex subunit RAP80 (Receptor-associated protein 80) (Retinoid X receptor-interacting protein 110) (Ubiquitin interaction motif-containing protein 1)

Gene: UIMC1
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q96RL1

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006282 - regulation of DNA repair
GO:0006302 - double-strand break repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508473

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

25

2

Small-scale

0.991

High

931583

RD23A
UV excision repair protein RAD23 homolog A

3

1

Small-scale

0.843

High

1248946

ABRX1
BRCA1-A complex subunit Abraxas 1

21

1

Small-scale

0.767

High

799415

BRCA1
Breast cancer type 1 susceptibility protein

18

2

Small-scale

0.764

High

858801

BRCC3
Lys-63-specific deubiquitinase BRCC36

13

0

Small-scale

0.728

High

1401501

BABA1
BRISC and BRCA1-A complex member 1

9

0

Small-scale

0.722

High

1401503

BABA2
BRISC and BRCA1-A complex member 2

8

0

Small-scale

0.717

High

964424

SUMO2
Small ubiquitin-related modifier 2

4

1

Small-scale

0.692

High

1129706

MDC1
Mediator of DNA damage checkpoint protein 1

4

2

Small-scale

0.692

High

396759

ESR1
Estrogen receptor

3

1

Small-scale

0.665

High

242657

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.665

High

507326

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

2

Small-scale

0.647

High

159810

DVL2
Segment polarity protein dishevelled homolog DVL-2

3

0

High-throughput

0.630

High

443484

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.618

High

1058220

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

Small-scale

0.605

High

1401502

COMD8
COMM domain-containing protein 8

2

0

High-throughput

0.602

High

1401494

TRAIP
E3 ubiquitin-protein ligase TRAIP

2

0

Small-scale

0.598

High

414449

P53
Cellular tumor antigen p53

2

0

Small-scale

0.598

High

1371370

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

2

0

Small-scale

0.598

High

1307387

RIOX2
Ribosomal oxygenase 2

2

0

High-throughput

0.585

High

1401491

BARD1
BRCA1-associated RING domain protein 1

2

0

Small-scale

0.585

High

487654

PARP1
Poly [ADP-ribose] polymerase 1

2

1

Small-scale

0.584

High

981029

H2B1C
Histone H2B type 1-C/E/F/G/I

2

1

High-throughput

0.584

High

998710

H31
Histone H3.1

2

1

High-throughput

0.584

High

1162873

H2A2C
Histone H2A type 2-C

2

0

Small-scale

0.569

High

185229

FANCG
Fanconi anemia group G protein

1

0

Small-scale

0.554

High

1123591

ZMYM3
Zinc finger MYM-type protein 3

1

0

High-throughput

0.537

High

783647

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

2

High-throughput

0.536

High

1100972

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.536

High

1136936

ABRX2
BRISC complex subunit Abraxas 2

1

1

High-throughput

0.536

High

1348710

UBA3
NEDD8-activating enzyme E1 catalytic subunit

1

1

High-throughput

0.536

High

390147

ALBU
Albumin

1

0

High-throughput

0.513

High

629156

CCNA2
Cyclin-A2

1

0

High-throughput

0.513

High

650569

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

0

High-throughput

0.513

High

769767

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.513

High

788157

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

859033

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

958698

CSN2
COP9 signalosome complex subunit 2

1

0

High-throughput

0.513

High

1117640

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.513

High

1347144

WDR48
WD repeat-containing protein 48

1

0

High-throughput

0.513

High

1401490

CTIP
DNA endonuclease RBBP8

1

0

Small-scale

0.513

High

1401492

CPNE1
Copine-1

1

0

High-throughput

0.513

High

1401495

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.513

High

1401498

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

High-throughput

0.513

High

1401505

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.513

High

1401507

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

1401508

SPAT2
Spermatogenesis-associated protein 2

1

0

High-throughput

0.513

High

1148267

NR6A1
Nuclear receptor subfamily 6 group A member 1

1

2

Small-scale

0.501

High

926399

BLM
RecQ-like DNA helicase BLM

1

0

Small-scale

0.493

High

791643

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

1401510

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

1110850

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

1

High-throughput

0.489

High

1197067

AMOT
Angiomotin

1

1

High-throughput

0.489

High

1401500

LIN7C
Protein lin-7 homolog C

1

1

High-throughput

0.489

High

1401509

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.489

High

555516

SKIL
Ski-like protein

1

0

High-throughput

0.486

High

1401499

AT8A2
Phospholipid-transporting ATPase IB

1

0

Small-scale

0.480

High

991404

SUMO1
Small ubiquitin-related modifier 1

1

1

Small-scale

0.479

High

1017140

H33
Histone H3.3

1

1

High-throughput

0.479

High

1088981

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1163155

H2B2E
Histone H2B type 2-E

1

1

Small-scale

0.479

High

1257104

PAXI1
PAX-interacting protein 1

1

2

High-throughput

0.479

High

1364214

TOPB1
DNA topoisomerase 2-binding protein 1

1

2

High-throughput

0.479

High

1367073

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1219327

ECM29
Proteasome adapter and scaffold protein ECM29

1

0

Small-scale

0.460

High

1368456

CBP
CREB-binding protein

1

0

Small-scale

0.460

High

1381230

WBP2
WW domain-binding protein 2

1

0

Small-scale

0.460

High

170299

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

260333

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

321640

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.458

High

589464

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

696271

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

703190

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.458

High

714364

PML
Protein PML

1

0

High-throughput

0.458

High

761832

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

768948

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

786798

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.458

High

975881

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

979157

RS6
Small ribosomal subunit protein eS6

1

0

Small-scale

0.458

High

980178

H4
Histone H4

1

0

High-throughput

0.458

High

986652

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1004999

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1028347

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

1045667

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1097508

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1114072

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1137961

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1141880

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

1246941

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1255155

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1276673

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1289556

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1313358

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1401497

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1401504

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1401506

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

993718

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.457

High

1401496

IN80B
INO80 complex subunit B

1

0

High-throughput

0.438

High

1199940

P5CR3
Pyrroline-5-carboxylate reductase 3

1

1

High-throughput

0.437

High

81647

B5MD87
pyrroline-5-carboxylate reductase

1

1

High-throughput

0.407

High

1316530

Q8IZK2
Breast and ovarian cancer susceptibility protein

1

1

High-throughput

0.407

High

168735

CSKP
Peripheral plasma membrane protein CASK

1

0

High-throughput

0.279

Low

176703

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.279

Low

181016

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

1

0

High-throughput

0.279

Low

229556

NRDC
Nardilysin

1

0

High-throughput

0.279

Low

475490

FA7
Coagulation factor VII

1

0

High-throughput

0.279

Low

706272

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

867360

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

915167

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.279

Low

1239088

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

1

0

High-throughput

0.279

Low

1315345

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.279

Low

1401493

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.279

Low

1123777

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.268

Low

939410

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.249

Low

1252941

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1155177

EREP1
Endosomal transmembrane epsin interactor 1

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025