Protein: RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1 (40S ribosomal protein S4)

Gene: RS4Y1, RPS4Y1
Organism: Homo sapiens
Interactions: 87
UniProt ID: P22090

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

644201

RS4Y2
Small ribosomal subunit protein eS4, Y isoform 2

5

6

High-throughput

0.915

High

644186

RS4X
Small ribosomal subunit protein eS4, X isoform

4

6

High-throughput

0.873

High

644188

RS6
Small ribosomal subunit protein eS6

3

3

High-throughput

0.640

High

644183

PRPS1
Ribose-phosphate pyrophosphokinase 1

3

0

High-throughput

0.628

High

644171

RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1

1

6

High-throughput

0.618

High

391182

FRIL
Ferritin light chain

1

1

High-throughput

0.536

High

644173

RS19
Small ribosomal subunit protein eS19

1

4

High-throughput

0.536

High

644184

ARP3
Actin-related protein 3

1

1

High-throughput

0.536

High

644185

RS8
Small ribosomal subunit protein eS8

1

3

High-throughput

0.536

High

644189

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.536

High

644214

TCAB1
Telomerase Cajal body protein 1

1

5

High-throughput

0.536

High

644215

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.536

High

644217

YTHD1
YTH domain-containing family protein 1

1

1

High-throughput

0.536

High

644238

WDR37
WD repeat-containing protein 37

1

4

High-throughput

0.536

High

644240

NGN3
Neurogenin-3

1

1

High-throughput

0.536

High

123329

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.513

High

269903

SDC3
Syndecan-3

1

0

High-throughput

0.513

High

402522

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.513

High

644172

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.513

High

644174

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.513

High

644177

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.513

High

644187

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

644190

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.513

High

644208

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.513

High

644210

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

644213

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.513

High

644223

RBSK
Ribokinase

1

0

High-throughput

0.513

High

644229

HINT3
Adenosine 5'-monophosphoramidase HINT3

1

0

High-throughput

0.513

High

644239

NEUR2
Sialidase-2

1

0

High-throughput

0.513

High

644178

CLK1
Dual specificity protein kinase CLK1

1

1

High-throughput

0.501

High

644236

PADI4
Protein-arginine deiminase type-4

1

0

High-throughput

0.493

High

207795

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

4

High-throughput

0.489

High

239011

ZNRD2
Protein ZNRD2

1

2

High-throughput

0.489

High

644196

HECD3
E3 ubiquitin-protein ligase HECTD3

1

8

High-throughput

0.489

High

644233

ARP3B
Actin-related protein 3B

1

1

High-throughput

0.489

High

644179

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

156957

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.479

High

222720

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.479

High

324526

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

330660

KI20A
Kinesin-like protein KIF20A

1

8

High-throughput

0.479

High

371164

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

427803

ICAM1
Intercellular adhesion molecule 1

1

2

High-throughput

0.479

High

519742

ANDR
Androgen receptor

1

5

High-throughput

0.479

High

644175

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

644176

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

644180

CDK7
Cyclin-dependent kinase 7

1

2

High-throughput

0.479

High

644182

CD81
CD81 antigen

1

1

High-throughput

0.479

High

644191

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.479

High

644193

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

644194

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.479

High

644195

LARP7
La-related protein 7

1

5

High-throughput

0.479

High

644197

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

644199

MEPCE
7SK snRNA methylphosphate capping enzyme

1

2

High-throughput

0.479

High

644200

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.479

High

644203

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

644204

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.479

High

644205

IGSF8
Immunoglobulin superfamily member 8

1

2

High-throughput

0.479

High

644206

CHM4C
Charged multivesicular body protein 4c

1

5

High-throughput

0.479

High

644209

AURKB
Aurora kinase B

1

3

High-throughput

0.479

High

644211

RUFY1
RUN and FYVE domain-containing protein 1

1

2

High-throughput

0.479

High

644212

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

644216

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

644218

NSD3
Histone-lysine N-methyltransferase NSD3

1

2

High-throughput

0.479

High

644221

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.479

High

644222

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.479

High

644225

ECT2
Protein ECT2

1

3

High-throughput

0.479

High

644227

CBX8
Chromobox protein homolog 8

1

1

High-throughput

0.479

High

644228

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

644230

ANLN
Anillin

1

2

High-throughput

0.479

High

644234

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

644192

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

644219

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

47489

RPSA2
Small ribosomal subunit protein uS2B

1

4

High-throughput

0.445

High

644226

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.445

High

644224

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

270086

TMCC2
Transmembrane and coiled-coil domains protein 2

1

0

High-throughput

0.279

Low

644181

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.279

Low

644231

CZIB
CXXC motif containing zinc binding protein

1

0

High-throughput

0.279

Low

644232

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.279

Low

644237

CAH5B
Carbonic anhydrase 5B, mitochondrial

1

0

High-throughput

0.279

Low

466999

DAF
Complement decay-accelerating factor

1

0

High-throughput

0.269

Low

644198

UD3A1
UDP-glucuronosyltransferase 3A1

1

0

High-throughput

0.269

Low

644207

PHIPL
Phytanoyl-CoA hydroxylase-interacting protein-like

1

0

High-throughput

0.269

Low

644235

KAD3
GTP:AMP phosphotransferase AK3, mitochondrial

1

0

High-throughput

0.269

Low

644202

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.249

Low

644220

S6A16
Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025