Protein: PRPH2
Peripherin-2 (Retinal degeneration slow protein) (Tetraspanin-22) (Tspan-22)

Gene: PRPH2
Organism: Homo sapiens
Interactions: 34
UniProt ID: P23942

Gene Ontology (top 5):
GO:0001750 - photoreceptor outer segment
GO:0001917 - photoreceptor inner segment
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007601 - visual perception

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

333442

MPZL1
Myelin protein zero-like protein 1

1

5

High-throughput

0.691

High

663503

NECT2
Nectin-2

1

3

High-throughput

0.691

High

163241

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

2

High-throughput

0.536

High

373778

RASN
GTPase NRas

1

6

High-throughput

0.536

High

564799

NCAM1
Neural cell adhesion molecule 1

1

3

High-throughput

0.536

High

663489

HMOX2
Heme oxygenase 2

1

3

High-throughput

0.536

High

663494

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

6

High-throughput

0.536

High

663495

SLMAP
Sarcolemmal membrane-associated protein

1

6

High-throughput

0.536

High

663497

ULBP6
UL16-binding protein 6

1

2

High-throughput

0.536

High

663498

POTEE
POTE ankyrin domain family member E

1

2

High-throughput

0.536

High

663499

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

1

1

High-throughput

0.536

High

663500

CPNE9
Copine-9

1

2

High-throughput

0.536

High

663505

RAB9B
Ras-related protein Rab-9B

1

2

High-throughput

0.536

High

663506

PDXL2
Podocalyxin-like protein 2

1

1

High-throughput

0.536

High

663508

ACSL6
Long-chain-fatty-acid--CoA ligase 6

1

1

High-throughput

0.536

High

663510

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

1

High-throughput

0.536

High

280508

PR40A
Pre-mRNA-processing factor 40 homolog A

1

1

High-throughput

0.515

High

561899

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.515

High

160685

TOR1A
Torsin-1A

1

0

High-throughput

0.513

High

162782

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

0

High-throughput

0.513

High

507084

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

0

High-throughput

0.513

High

569161

CD59
CD59 glycoprotein

1

0

High-throughput

0.513

High

663490

PCY1A
Choline-phosphate cytidylyltransferase A

1

0

High-throughput

0.513

High

663491

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.513

High

663502

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.513

High

663509

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

663501

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.489

High

663507

EXTL2
Exostosin-like 2

1

2

High-throughput

0.489

High

254814

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

663504

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.426

High

663492

CSTF3
Cleavage stimulation factor subunit 3

1

0

High-throughput

0.279

Low

441524

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

663493

SRSF5
Serine/arginine-rich splicing factor 5

1

0

Small-scale

0.249

Low

663496

TAF11
Transcription initiation factor TFIID subunit 11

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025