Protein: PDXL2
Podocalyxin-like protein 2 (Endoglycan)

Gene: PDXL2, PODXL2
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9NZ53

Gene Ontology (top 5):
GO:0005539 - glycosaminoglycan binding
GO:0005796 - Golgi lumen
GO:0005886 - plasma membrane
GO:0050901 - leukocyte tethering or rolling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

705998

CD1B
T-cell surface glycoprotein CD1b

3

2

High-throughput

0.667

High

1197898

S39AC
Zinc transporter ZIP12

3

1

High-throughput

0.662

High

619940

VCAM1
Vascular cell adhesion protein 1

2

2

High-throughput

0.628

High

1350321

RAE1E
Retinoic acid early transcript 1E

2

2

High-throughput

0.628

High

1453002

PCDGD
Protocadherin gamma-B1

2

1

High-throughput

0.628

High

749411

TNFL8
Tumor necrosis factor ligand superfamily member 8

2

0

High-throughput

0.602

High

1187226

CC50B
Cell cycle control protein 50B

2

0

High-throughput

0.602

High

939542

FCGRN
IgG receptor FcRn large subunit p51

2

1

High-throughput

0.574

High

1350271

RHPN1
Rhophilin-1

2

3

High-throughput

0.574

High

1432766

TMX1
Thioredoxin-related transmembrane protein 1

2

2

High-throughput

0.574

High

477476

CD63
CD63 antigen

1

1

High-throughput

0.536

High

663506

PRPH2
Peripherin-2

1

1

High-throughput

0.536

High

761303

RYK
Tyrosine-protein kinase RYK

1

6

High-throughput

0.536

High

1150494

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

8

High-throughput

0.536

High

1410021

PD1L2
Programmed cell death 1 ligand 2

1

1

High-throughput

0.536

High

1438715

CRLF2
Cytokine receptor-like factor 2

1

1

High-throughput

0.536

High

376647

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.513

High

596540

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.513

High

1090016

LMAN2
Vesicular integral-membrane protein VIP36

1

0

High-throughput

0.513

High

1116405

TPBG
Trophoblast glycoprotein

1

0

High-throughput

0.513

High

1390792

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.513

High

1453000

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.513

High

570765

LYAM1
L-selectin

1

4

Small-scale

0.501

High

162870

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

8

High-throughput

0.489

High

1138117

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.489

High

1450051

UFSP2
Ufm1-specific protease 2

1

1

High-throughput

0.489

High

126836

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

189883

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

218870

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

363942

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.479

High

376026

RASK
GTPase KRas

1

8

High-throughput

0.479

High

376557

LDLR
Low-density lipoprotein receptor

1

2

High-throughput

0.479

High

411087

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

7

High-throughput

0.479

High

953710

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

1015853

RHOG
Rho-related GTP-binding protein RhoG

1

19

High-throughput

0.479

High

1438198

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1452999

PDXL2
Podocalyxin-like protein 2

1

4

Small-scale

0.479

High

1369711

KLK6
Kallikrein-6

1

1

High-throughput

0.470

High

562452

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.458

High

774671

BASI
Basigin

1

0

High-throughput

0.458

High

787259

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.458

High

975283

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

948948

CD81
CD81 antigen

1

1

High-throughput

0.445

High

1251814

S39A5
Zinc transporter ZIP5

1

1

High-throughput

0.445

High

1308541

SL9A9
Sodium/hydrogen exchanger 9

1

3

High-throughput

0.445

High

1359511

CTL1
Choline transporter-like protein 1

1

1

High-throughput

0.445

High

1365134

SL9A6
Sodium/hydrogen exchanger 6

1

3

High-throughput

0.445

High

905214

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.437

High

976618

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.437

High

1005183

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1229723

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

1255854

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1447899

SAR1A
Small COPII coat GTPase SAR1A

1

7

High-throughput

0.437

High

1031875

LAT1
Large neutral amino acids transporter small subunit 1

1

0

High-throughput

0.426

High

1090038

NTCP2
Ileal sodium/bile acid cotransporter

1

0

High-throughput

0.426

High

1179035

S35G1
Solute carrier family 35 member G1

1

0

High-throughput

0.426

High

1408084

SC6A7
Sodium-dependent proline transporter

1

0

High-throughput

0.426

High

1439127

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.426

High

1186239

CEA21
Cell adhesion molecule CEACAM21

3

0

High-throughput

0.347

High

49822

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

1083161

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.279

Low

1259203

SMIM5
Small integral membrane protein 5

1

0

High-throughput

0.279

Low

1336533

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.279

Low

1430697

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

1453001

B3GT5
Beta-1,3-galactosyltransferase 5

1

0

High-throughput

0.279

Low

1398002

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025