Protein: MPZL1
Myelin protein zero-like protein 1 (Protein zero-related)

Gene: MPZL1
Organism: Homo sapiens
Interactions: 126
UniProt ID: O95297

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007267 - cell-cell signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

333441

LEG3
Galectin-3

4

9

High-throughput

0.892

High

333426

RASK
GTPase KRas

4

20

High-throughput

0.873

High

333424

RASN
GTPase NRas

3

20

High-throughput

0.827

High

333425

RASH
GTPase HRas

3

20

High-throughput

0.827

High

125115

LEG9
Galectin-9

3

9

High-throughput

0.770

High

333460

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

333448

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

2

0

High-throughput

0.736

High

333450

CBPA2
Carboxypeptidase A2

2

3

High-throughput

0.726

High

333452

FCGRN
IgG receptor FcRn large subunit p51

2

2

High-throughput

0.726

High

333502

CBPA5
Carboxypeptidase A5

2

3

High-throughput

0.726

High

333440

CTLA4
Cytotoxic T-lymphocyte protein 4

1

1

High-throughput

0.691

High

333442

PRPH2
Peripherin-2

1

5

High-throughput

0.691

High

333445

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

1

High-throughput

0.691

High

333489

BTNL9
Butyrophilin-like protein 9

1

9

High-throughput

0.691

High

333490

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.691

High

333522

CRLF2
Cytokine receptor-like factor 2

1

3

High-throughput

0.691

High

333535

CLC4A
C-type lectin domain family 4 member A

1

5

High-throughput

0.691

High

333487

S39A4
Zinc transporter ZIP4

4

9

High-throughput

0.691

High

333469

TSN31
Tetraspanin-31

1

0

High-throughput

0.656

High

333531

GPC5D
G-protein coupled receptor family C group 5 member D

1

0

High-throughput

0.656

High

333534

FZD4
Frizzled-4

1

0

High-throughput

0.656

High

333466

PTN11
Tyrosine-protein phosphatase non-receptor type 11

4

20

Small-scale

0.633

High

333479

CC50B
Cell cycle control protein 50B

2

1

High-throughput

0.628

High

333518

PACC1
Proton-activated chloride channel

2

1

High-throughput

0.628

High

333472

FHL3
Four and a half LIM domains protein 3

1

2

High-throughput

0.621

High

333480

ACTBL
Beta-actin-like protein 2

1

4

High-throughput

0.618

High

333492

AMGO1
Amphoterin-induced protein 1

1

3

High-throughput

0.618

High

333496

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

2

High-throughput

0.618

High

333510

LST8
Target of rapamycin complex subunit LST8

1

3

High-throughput

0.618

High

333512

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

2

High-throughput

0.618

High

126417

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

333423

DIRA3
GTP-binding protein Di-Ras3

1

5

High-throughput

0.618

High

333431

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

333434

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.618

High

333436

CADH1
Cadherin-1

1

8

High-throughput

0.618

High

333439

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

333444

EPHA2
Ephrin type-A receptor 2

1

7

High-throughput

0.618

High

333447

MUC18
Cell surface glycoprotein MUC18

1

11

High-throughput

0.618

High

333455

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

333456

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

333458

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

333461

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

333462

CXAR
Coxsackievirus and adenovirus receptor

1

10

High-throughput

0.618

High

333464

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

333475

RAB35
Ras-related protein Rab-35

1

5

High-throughput

0.618

High

333476

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

333517

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

333520

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

333488

TMM65
Transmembrane protein 65

2

1

High-throughput

0.612

High

333521

SACA1
Sperm acrosome membrane-associated protein 1

3

1

High-throughput

0.609

High

333532

GGT7
Glutathione hydrolase 7

2

0

High-throughput

0.602

High

333498

LY65B
Lymphocyte antigen 6 complex locus protein G5b

1

0

High-throughput

0.578

High

333454

CD81
CD81 antigen

1

10

High-throughput

0.575

High

333435

PSPC
Surfactant protein C

2

2

High-throughput

0.574

High

333495

SIGL1
SIGLEC family-like protein 1

2

1

High-throughput

0.574

High

333508

CP2S1
Cytochrome P450 2S1

2

2

High-throughput

0.574

High

333457

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.553

High

170595

CLGN
Calmegin

2

4

High-throughput

0.549

High

333505

SAAL1
Protein SAAL1

2

5

High-throughput

0.549

High

333427

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

1

High-throughput

0.536

High

333433

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.536

High

333526

PICK1
PRKCA-binding protein

1

5

High-throughput

0.536

High

333536

BAIP2
BAR/IMD domain-containing adapter protein 2

1

1

High-throughput

0.536

High

333481

DCAF6
DDB1- and CUL4-associated factor 6

1

0

High-throughput

0.517

High

333515

TOLIP
Toll-interacting protein

1

0

High-throughput

0.517

High

333499

MFSD8
Major facilitator superfamily domain-containing protein 8

1

2

High-throughput

0.514

High

333506

MF14A
Hippocampus abundant transcript 1 protein

1

2

High-throughput

0.514

High

333428

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

333500

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.513

High

164500

TNPO2
Transportin-2

1

14

High-throughput

0.489

High

333438

DHB1
17-beta-hydroxysteroid dehydrogenase type 1

1

3

High-throughput

0.489

High

333443

CALX
Calnexin

1

4

High-throughput

0.489

High

333449

CRKL
Crk-like protein

1

5

High-throughput

0.489

High

333467

VAC14
Protein VAC14 homolog

1

19

High-throughput

0.489

High

333478

KIF7
Kinesin-like protein KIF7

1

1

High-throughput

0.489

High

333482

NHLC3
NHL repeat-containing protein 3

1

1

High-throughput

0.489

High

333507

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.481

High

333446

STAT3
Signal transducer and activator of transcription 3

1

1

High-throughput

0.481

High

189361

STX7
Syntaxin-7

1

4

High-throughput

0.479

High

217657

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

333430

LYN
Tyrosine-protein kinase Lyn

1

5

High-throughput

0.479

High

333437

SRC
Proto-oncogene tyrosine-protein kinase Src

1

5

Small-scale

0.479

High

333453

ARL4C
ADP-ribosylation factor-like protein 4C

1

11

High-throughput

0.479

High

333459

ARF6
ADP-ribosylation factor 6

1

5

High-throughput

0.479

High

333465

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

333468

STX4
Syntaxin-4

1

4

High-throughput

0.479

High

333485

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

333494

ARL14
ADP-ribosylation factor-like protein 14

1

7

High-throughput

0.479

High

333497

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.479

High

333516

CCDC8
Coiled-coil domain-containing protein 8

1

3

High-throughput

0.479

High

333527

T106B
Transmembrane protein 106B

1

2

High-throughput

0.479

High

333537

FBX7
F-box only protein 7

1

1

High-throughput

0.457

High

333432

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

333470

TRDN
Triadin

1

5

High-throughput

0.445

High

333474

S39AE
Metal cation symporter ZIP14

1

9

High-throughput

0.445

High

333523

ANKH
Mineralization regulator ANKH

1

1

High-throughput

0.445

High

333533

S39AA
Zinc transporter ZIP10

1

9

High-throughput

0.445

High

333503

TRI63
E3 ubiquitin-protein ligase TRIM63

1

9

High-throughput

0.439

High

333511

TRI55
Tripartite motif-containing protein 55

1

9

High-throughput

0.439

High

181673

CTDSL
CTD small phosphatase-like protein

1

2

High-throughput

0.437

High

333463

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

333491

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

2

High-throughput

0.437

High

333493

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

333504

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

333529

ARL15
ADP-ribosylation factor-like protein 15

1

11

High-throughput

0.437

High

333501

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.426

High

109140

G4U4J3
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.407

High

333429

LIPF
Gastric triacylglycerol lipase

3

0

High-throughput

0.347

High

333451

CCHL
Holocytochrome c-type synthase

3

0

High-throughput

0.347

High

333486

NXRD1
NADP-dependent oxidoreductase domain-containing protein 1

3

0

High-throughput

0.342

High

333471

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.328

High

333519

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.328

High

333514

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

280893

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

317230

AL1A2
Retinal dehydrogenase 2

1

0

High-throughput

0.279

Low

333473

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.279

Low

333483

PLAC9
Placenta-specific protein 9

1

0

High-throughput

0.279

Low

333484

CF136
Uncharacterized protein C6orf136

1

0

High-throughput

0.279

Low

333509

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.279

Low

333513

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

1

0

High-throughput

0.279

Low

333525

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.279

Low

333528

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.279

Low

333530

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.279

Low

333477

DOK7
Protein Dok-7

1

0

High-throughput

0.251

Low

333524

EXOS4
Exosome complex component RRP41

1

0

High-throughput

0.251

Low

292979

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025