Protein: IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein (Protein DANGER)

Gene: IPRI, ITPRIP
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q8IWB1

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0005640 - nuclear outer membrane
GO:0005886 - plasma membrane
GO:0008625 - extrinsic apoptotic signaling pathway via death domain receptors
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1309806

RASF1
Ras association domain-containing protein 1

4

3

High-throughput

0.638

High

705972

CD1B
T-cell surface glycoprotein CD1b

3

0

High-throughput

0.638

High

181365

PGRC2
Membrane-associated progesterone receptor component 2

3

0

High-throughput

0.636

High

1309796

ASIC4
Acid-sensing ion channel 4

3

0

High-throughput

0.634

High

406904

MAS
Proto-oncogene Mas

2

2

High-throughput

0.628

High

855349

5HT3A
5-hydroxytryptamine receptor 3A

2

5

High-throughput

0.628

High

1309790

5HT3C
5-hydroxytryptamine receptor 3C

2

4

High-throughput

0.611

High

1292460

RASF3
Ras association domain-containing protein 3

2

2

High-throughput

0.606

High

1309795

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

4

High-throughput

0.606

High

968982

PRS8
26S proteasome regulatory subunit 8

2

0

High-throughput

0.602

High

1244878

NCEH1
Neutral cholesterol ester hydrolase 1

2

0

High-throughput

0.602

High

1294971

LRC33
Transforming growth factor beta activator LRRC33

2

0

High-throughput

0.602

High

638466

FPR1
fMet-Leu-Phe receptor

2

3

High-throughput

0.601

High

1254530

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.553

High

1309808

NLGN3
Neuroligin-3

1

0

Small-scale

0.549

High

210406

MTLR
Motilin receptor

1

1

High-throughput

0.536

High

332362

5HT3B
5-hydroxytryptamine receptor 3B

1

6

High-throughput

0.536

High

663499

PRPH2
Peripherin-2

1

1

High-throughput

0.536

High

1048797

ACHE
Acetylcholine receptor subunit epsilon

1

3

High-throughput

0.536

High

1093146

STK4
Serine/threonine-protein kinase 4

1

3

High-throughput

0.536

High

1196201

S22A6
Solute carrier family 22 member 6

1

1

High-throughput

0.536

High

1309804

CRLF2
Cytokine receptor-like factor 2

1

1

High-throughput

0.536

High

1309809

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.536

High

1309810

P2RX2
P2X purinoceptor 2

1

1

High-throughput

0.536

High

1309816

PCDB7
Protocadherin beta-7

1

4

High-throughput

0.536

High

1309817

PCDBB
Protocadherin beta-11

1

4

High-throughput

0.536

High

1309818

PCDB1
Protocadherin beta-1

1

3

High-throughput

0.536

High

1309819

PCDGM
Protocadherin gamma-C5

1

2

High-throughput

0.536

High

252358

TLR2
Toll-like receptor 2

1

0

High-throughput

0.513

High

821739

CD79B
B-cell antigen receptor complex-associated protein beta chain

1

0

High-throughput

0.513

High

1133839

KI2S3
Killer cell immunoglobulin-like receptor 2DS3

1

0

High-throughput

0.513

High

1286822

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.513

High

1309813

BTNL2
Butyrophilin-like protein 2

1

0

High-throughput

0.513

High

191448

SIA8E
Alpha-2,8-sialyltransferase 8E

1

1

High-throughput

0.489

High

1309791

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

1

1

High-throughput

0.489

High

1309787

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.479

High

1309801

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1309811

TES
Testin

1

0

High-throughput

0.458

High

1309814

AT1B4
Protein ATP1B4

1

0

High-throughput

0.458

High

844824

EAA1
Excitatory amino acid transporter 1

1

2

High-throughput

0.445

High

886096

CXCR3
C-X-C chemokine receptor type 3

1

1

High-throughput

0.445

High

1101575

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

2

High-throughput

0.445

High

1131566

MFS10
Major facilitator superfamily domain-containing protein 10

1

3

High-throughput

0.445

High

1309788

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

1

High-throughput

0.445

High

1309792

S39A7
Zinc transporter SLC39A7

1

2

High-throughput

0.445

High

1309793

LPAR1
Lysophosphatidic acid receptor 1

1

4

High-throughput

0.445

High

1309794

S67A1
Solute carrier family 67 member A1

1

1

High-throughput

0.445

High

1309799

S1PR3
Sphingosine 1-phosphate receptor 3

1

4

High-throughput

0.445

High

1309812

LAT2
Large neutral amino acids transporter small subunit 2

1

1

High-throughput

0.445

High

106232

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

538778

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.426

High

839046

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.426

High

870256

S6A12
Sodium- and chloride-dependent betaine transporter

1

0

High-throughput

0.426

High

914443

EFNB2
Ephrin-B2

1

0

High-throughput

0.426

High

1175875

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

0

High-throughput

0.426

High

1236212

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1273768

NIPA1
Magnesium transporter NIPA1

1

0

High-throughput

0.426

High

1309784

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.426

High

1309785

AGRG5
Adhesion G-protein coupled receptor G5

1

0

High-throughput

0.426

High

1309815

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.426

High

1211927

S35F1
Solute carrier family 35 member F1

1

1

High-throughput

0.407

High

1308890

S22A9
Organic anion transporter 7

1

1

High-throughput

0.407

High

1309798

TECT2
Tectonic-2

2

0

High-throughput

0.328

High

934015

PLTP
Phospholipid transfer protein

2

0

High-throughput

0.318

High

822157

PSB10
Proteasome subunit beta type-10

1

0

High-throughput

0.279

Low

1309786

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

0

High-throughput

0.279

Low

1309789

TMED6
Transmembrane emp24 domain-containing protein 6

1

0

High-throughput

0.279

Low

1309807

GALT8
Probable polypeptide N-acetylgalactosaminyltransferase 8

1

0

High-throughput

0.279

Low

293976

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

385934

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.249

Low

1004794

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1252884

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1309800

Q9BPW0
Serine/threonine-protein phosphatase

1

0

High-throughput

0.249

Low

1309803

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.249

Low

1309805

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

1309797

BSCL2
Seipin

1

0

High-throughput

0.232

Low

1309802

ZDH11
Palmitoyltransferase ZDHHC11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025