Protein: SOSD1
Sclerostin domain-containing protein 1 (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1)

Gene: SOSD1, SOSTDC1
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q6X4U4

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0007389 - pattern specification process
GO:0010454 - negative regulation of cell fate commitment
GO:0030178 - negative regulation of Wnt signaling pathway
GO:0030514 - negative regulation of BMP signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

554232

BMP4
Bone morphogenetic protein 4

2

2

Small-scale

0.584

High

554135

BMP2
Bone morphogenetic protein 2

1

2

Small-scale

0.479

High

611740

BMP7
Bone morphogenetic protein 7

1

2

Small-scale

0.479

High

767093

SPB6
Serpin B6

1

1

Small-scale

0.479

High

1250899

SPB12
Serpin B12

1

1

Small-scale

0.479

High

162843

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

0

Small-scale

0.458

High

552993

PIP
Prolactin-inducible protein

1

0

Small-scale

0.458

High

1250894

SOSD1
Sclerostin domain-containing protein 1

1

0

Small-scale

0.458

High

1250900

ATX10
Ataxin-10

1

0

Small-scale

0.458

High

281052

TACC1
Transforming acidic coiled-coil-containing protein 1

1

2

Small-scale

0.437

High

334302

TACC2
Transforming acidic coiled-coil-containing protein 2

1

1

Small-scale

0.437

High

445633

CEAM5
Cell adhesion molecule CEACAM5

1

0

Small-scale

0.249

Low

728303

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.249

Low

839303

MTOR
Serine/threonine-protein kinase mTOR

1

0

Small-scale

0.249

Low

845320

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

0

Small-scale

0.249

Low

887436

CEBPD
CCAAT/enhancer-binding protein delta

1

0

Small-scale

0.249

Low

948439

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

Small-scale

0.249

Low

958661

CSN2
COP9 signalosome complex subunit 2

1

0

Small-scale

0.249

Low

988462

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

Small-scale

0.249

Low

1116963

CD166
CD166 antigen

1

0

Small-scale

0.249

Low

1120748

DSG2
Desmoglein-2

1

0

Small-scale

0.249

Low

1143167

PLEC
Plectin

1

0

Small-scale

0.249

Low

1250895

BCAP
Phosphoinositide 3-kinase adapter protein 1

1

0

Small-scale

0.249

Low

1250896

POF1B
Protein POF1B

1

0

Small-scale

0.249

Low

1250897

ARL8A
ADP-ribosylation factor-like protein 8A

1

0

Small-scale

0.249

Low

1250898

DOCK7
Dedicator of cytokinesis protein 7

1

0

Small-scale

0.249

Low

1250901

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

Small-scale

0.249

Low

1250902

TLN2
Talin-2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025