Protein: ALG1
Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase) (Mannosyltransferase-1) (MT-1) (hMat-1)

Gene: ALG1
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q9BT22

Gene Ontology (top 5):
GO:0000030 - mannosyltransferase activity
GO:0004578 - chitobiosyldiphosphodolichol beta-mannosyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006486 - protein glycosylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

242753

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

564300

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

1413058

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

508534

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

1294249

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.479

High

1334533

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

1413061

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.479

High

347902

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

488850

FURIN
Furin

1

0

High-throughput

0.458

High

693071

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

774587

BASI
Basigin

1

0

High-throughput

0.458

High

932594

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

0

High-throughput

0.458

High

1114153

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1249168

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1252959

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1276295

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1403562

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1413052

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

412525

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.457

High

1157052

NTRK3
NT-3 growth factor receptor

1

1

High-throughput

0.457

High

211172

CTR4
Cationic amino acid transporter 4

1

2

High-throughput

0.445

High

1139552

S39AE
Metal cation symporter ZIP14

1

2

High-throughput

0.445

High

1413053

S39A8
Metal cation symporter ZIP8

1

2

High-throughput

0.445

High

1286888

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.437

High

1413056

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

303279

S22A5
Organic cation/carnitine transporter 2

1

0

High-throughput

0.426

High

1413055

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

0

High-throughput

0.426

High

944058

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

1197876

S39AC
Zinc transporter ZIP12

1

2

High-throughput

0.407

High

1361297

CTR3
Cationic amino acid transporter 3

1

2

High-throughput

0.407

High

218701

TGON2
Trans-Golgi network integral membrane protein 2

3

0

High-throughput

0.330

High

1259463

TBA1A
Tubulin alpha-1A chain

2

0

High-throughput

0.298

High

1310358

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1413065

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.279

Low

164429

NRP1
Neuropilin-1

1

0

High-throughput

0.249

Low

294263

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

589555

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

831333

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

861272

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.249

Low

927118

ATX3
Ataxin-3

1

0

Small-scale

0.249

Low

1005035

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1163897

DUS7
Dual specificity protein phosphatase 7

1

0

High-throughput

0.249

Low

1178345

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1255300

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1281057

VTCN1
V-set domain-containing T-cell activation inhibitor 1

1

0

Small-scale

0.249

Low

1312591

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1397378

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

1413054

TOLIP
Toll-interacting protein

1

0

High-throughput

0.249

Low

1413057

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1413059

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1413060

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

1413062

KS6B2
Ribosomal protein S6 kinase beta-2

1

0

High-throughput

0.249

Low

1413063

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

652243

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

0

High-throughput

0.232

Low

1157195

S15A2
Solute carrier family 15 member 2

1

0

High-throughput

0.232

Low

1227367

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

1260507

S35D2
Nucleotide sugar transporter SLC35D2

1

0

High-throughput

0.232

Low

1413064

S23A1
Solute carrier family 23 member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025