Protein: OPA3
Optic atrophy 3 protein

Gene: OPA3
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q9H6K4

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0007005 - mitochondrion organization
GO:0007601 - visual perception
GO:0019216 - regulation of lipid metabolic process
GO:0040008 - regulation of growth

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1435007

PCDGD
Protocadherin gamma-B1

3

3

High-throughput

0.604

High

1435006

PCDGE
Protocadherin gamma-B2

2

3

High-throughput

0.549

High

1403427

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.536

High

1435004

PCDGG
Protocadherin gamma-B4

1

3

High-throughput

0.489

High

228858

SCO2
Protein SCO2 homolog, mitochondrial

1

1

High-throughput

0.479

High

296302

SCO1
Protein SCO1 homolog, mitochondrial

1

1

High-throughput

0.479

High

575202

IDE
Insulin-degrading enzyme

1

1

High-throughput

0.479

High

1397654

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

1435005

PCDGI
Protocadherin gamma-B6

1

3

High-throughput

0.470

High

168122

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

1

0

High-throughput

0.458

High

348736

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.458

High

617600

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.458

High

634180

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.458

High

680507

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

784723

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

869983

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.458

High

1058275

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1092644

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.458

High

1367277

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1403729

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.458

High

1429489

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.458

High

1432308

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1435000

OPA3
Optic atrophy 3 protein

1

0

High-throughput

0.458

High

1435001

STAR7
StAR-related lipid transfer protein 7, mitochondrial

1

0

High-throughput

0.458

High

1435003

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.458

High

1435008

MTCH2
Mitochondrial carrier homolog 2

1

0

High-throughput

0.458

High

229569

NRDC
Nardilysin

1

1

High-throughput

0.437

High

1035493

TNR17
Tumor necrosis factor receptor superfamily member 17

2

0

High-throughput

0.328

High

1036251

NRG1
Pro-neuregulin-1, membrane-bound isoform

2

0

High-throughput

0.318

High

854582

S15A1
Solute carrier family 15 member 1

2

0

High-throughput

0.313

High

1243403

TM154
Transmembrane protein 154

2

0

High-throughput

0.313

High

1435002

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

2

0

High-throughput

0.313

High

388297

GLPA
Glycophorin-A

1

0

High-throughput

0.279

Low

536290

PPAL
Lysosomal acid phosphatase

1

0

High-throughput

0.279

Low

1249508

VSTM1
V-set and transmembrane domain-containing protein 1

1

0

High-throughput

0.279

Low

216543

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.265

Low

246949

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.265

Low

1396929

ANM6
Protein arginine N-methyltransferase 6

1

0

High-throughput

0.265

Low

423172

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

508632

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.261

Low

535892

LAMC1
Laminin subunit gamma-1

1

0

High-throughput

0.249

Low

1258944

H32
Histone H3.2

1

0

High-throughput

0.249

Low

1390463

PHIPL
Phytanoyl-CoA hydroxylase-interacting protein-like

1

0

High-throughput

0.249

Low

1393696

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1093576

TRDN
Triadin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025