Protein: HOP2
Homologous-pairing protein 2 homolog (Nuclear receptor coactivator GT198) (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein) (Tat-binding protein 1-interacting protein) (TBP-1-interacting protein)

Gene: HOP2, PSMC3IP
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q9P2W1

Gene Ontology (top 5):
GO:0000709 - meiotic joint molecule formation
GO:0000794 - condensed nuclear chromosome
GO:0003690 - double-stranded DNA binding
GO:0003713 - transcription coactivator activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1416358

MND1
Meiotic nuclear division protein 1 homolog

7

3

Small-scale

0.967

High

220032

XRCC3
DNA repair protein XRCC3

1

3

High-throughput

0.541

High

397122

ESR1
Estrogen receptor

1

1

High-throughput

0.541

High

170398

AURKA
Aurora kinase A

1

0

High-throughput

0.518

High

355042

CHK2
Serine/threonine-protein kinase Chk2

1

0

High-throughput

0.518

High

411097

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

0

High-throughput

0.518

High

1047766

NOTC2
Neurogenic locus notch homolog protein 2

1

0

High-throughput

0.518

High

1439490

BRMS1
Breast cancer metastasis-suppressor 1

1

0

High-throughput

0.518

High

573902

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.513

High

1054660

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

1259291

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.513

High

1332122

EIF1A
Probable RNA-binding protein EIF1AD

1

0

High-throughput

0.513

High

1454848

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.513

High

404504

GCR
Glucocorticoid receptor

1

1

Small-scale

0.479

High

1055990

RAD51
DNA repair protein RAD51 homolog 1

1

3

Small-scale

0.479

High

1260632

ASXL2
Putative Polycomb group protein ASXL2

1

2

High-throughput

0.479

High

1312436

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.479

High

1454849

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.460

High

373380

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

607667

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

0

High-throughput

0.458

High

610495

PRS6A
26S proteasome regulatory subunit 6A

1

0

Small-scale

0.458

High

1387744

MBD6
Methyl-CpG-binding domain protein 6

1

0

High-throughput

0.458

High

1421201

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.437

High

294896

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

0

High-throughput

0.282

High

376915

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.282

High

648709

FGFR4
Fibroblast growth factor receptor 4

1

0

High-throughput

0.282

High

839100

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.282

High

1132456

CASP8
Caspase-8

1

0

High-throughput

0.282

High

1352001

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.282

High

300700

KRT37
Keratin, type I cuticular Ha7

1

0

High-throughput

0.279

Low

706342

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1410542

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

1430451

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.269

Low

556391

CADH1
Cadherin-1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025