Protein: KXDL1
KxDL motif-containing protein 1

Gene: KXDL1, KXD1
Organism: Homo sapiens
Interactions: 182
UniProt ID: Q9BQD3

Gene Ontology (top 5):
GO:0016192 - vesicle-mediated transport
GO:0032418 - lysosome localization
GO:0051036 - regulation of endosome size
GO:0062196 - regulation of lysosome size
GO:0072384 - organelle transport along microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1392334

BORC6
BLOC-1-related complex subunit 6

7

2

High-throughput

0.744

High

482960

TPM1
Tropomyosin alpha-1 chain

9

7

High-throughput

0.692

High

447847

TPM3
Tropomyosin alpha-3 chain

7

7

High-throughput

0.688

High

1008492

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

3

2

High-throughput

0.650

High

1410526

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

3

2

High-throughput

0.616

High

1386116

LRC45
Leucine-rich repeat-containing protein 45

3

1

High-throughput

0.609

High

610453

PRS6A
26S proteasome regulatory subunit 6A

3

1

High-throughput

0.609

High

1410521

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

3

2

High-throughput

0.604

High

1410519

MLP3B
Microtubule-associated protein 1 light chain 3 beta

2

2

High-throughput

0.590

High

1398340

CEP63
Centrosomal protein of 63 kDa

2

1

High-throughput

0.578

High

333394

SNAPN
SNARE-associated protein Snapin

2

0

High-throughput

0.576

High

1246499

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

2

0

High-throughput

0.576

High

1351266

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

2

0

High-throughput

0.576

High

1380381

BORC5
BLOC-1-related complex subunit 5

2

0

High-throughput

0.576

High

1384072

BORC7
BLOC-1-related complex subunit 7

2

0

High-throughput

0.576

High

1390560

BORC8
BLOC-1-related complex subunit 8

2

0

High-throughput

0.576

High

252908

EXOC3
Exocyst complex component 3

2

1

High-throughput

0.574

High

1330514

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

1

High-throughput

0.574

High

1395334

CC136
Coiled-coil domain-containing protein 136

2

5

High-throughput

0.574

High

1330173

CC185
Coiled-coil domain-containing protein 185

2

1

High-throughput

0.555

High

1124401

ELOA1
Elongin-A

2

1

High-throughput

0.553

High

131010

HIP1
Huntingtin-interacting protein 1

2

1

High-throughput

0.549

High

244867

TRAK2
Trafficking kinesin-binding protein 2

2

4

High-throughput

0.549

High

269605

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

2

1

High-throughput

0.549

High

281779

VP26A
Vacuolar protein sorting-associated protein 26A

2

1

High-throughput

0.549

High

1063167

GOGA3
Golgin subfamily A member 3

2

2

High-throughput

0.549

High

1122434

GIT2
ARF GTPase-activating protein GIT2

2

1

High-throughput

0.549

High

1134698

NUMA1
Nuclear mitotic apparatus protein 1

2

3

High-throughput

0.549

High

1135373

SLMAP
Sarcolemmal membrane-associated protein

2

4

High-throughput

0.549

High

1150943

TRIPB
Thyroid receptor-interacting protein 11

2

4

High-throughput

0.549

High

1194115

VP26B
Vacuolar protein sorting-associated protein 26B

2

1

High-throughput

0.549

High

1231953

MRCKG
Serine/threonine-protein kinase MRCK gamma

2

1

High-throughput

0.549

High

1289973

LUZP1
Leucine zipper protein 1

2

1

High-throughput

0.549

High

1290953

TAXB1
Tax1-binding protein 1

2

2

High-throughput

0.549

High

1293015

CDR2L
Cerebellar degeneration-related protein 2-like

2

1

High-throughput

0.549

High

1295407

RFIP4
Rab11 family-interacting protein 4

2

3

High-throughput

0.549

High

1396963

IFT74
Intraflagellar transport protein 74 homolog

2

4

High-throughput

0.549

High

1401153

SPAG5
Sperm-associated antigen 5

2

1

High-throughput

0.549

High

1402509

NEB2
Neurabin-2

2

2

High-throughput

0.549

High

1410515

FYCO1
FYVE and coiled-coil domain-containing protein 1

2

1

High-throughput

0.549

High

1410517

CP250
Centrosome-associated protein CEP250

2

2

High-throughput

0.549

High

1410536

NDE1
Nuclear distribution protein nudE homolog 1

2

1

High-throughput

0.549

High

1410553

3BP1
SH3 domain-binding protein 1

2

1

High-throughput

0.549

High

1410556

TRAF6
TNF receptor-associated factor 6

2

3

High-throughput

0.549

High

1410557

TACC3
Transforming acidic coiled-coil-containing protein 3

2

4

High-throughput

0.549

High

1087028

KIF5A
Kinesin heavy chain isoform 5A

1

1

High-throughput

0.536

High

1144869

RABE1
Rab GTPase-binding effector protein 1

1

1

High-throughput

0.536

High

902032

RAB9A
Ras-related protein Rab-9A

2

1

High-throughput

0.533

High

1233450

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.513

High

1314964

ELOA2
Elongin-A2

1

1

High-throughput

0.494

High

134956

EMAL1
Echinoderm microtubule-associated protein-like 1

1

1

High-throughput

0.489

High

180912

TIF1A
Transcription intermediary factor 1-alpha

1

1

High-throughput

0.489

High

272739

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

2

High-throughput

0.489

High

281091

TACC1
Transforming acidic coiled-coil-containing protein 1

1

2

High-throughput

0.489

High

300689

KRT37
Keratin, type I cuticular Ha7

1

2

High-throughput

0.489

High

300825

KRT38
Keratin, type I cuticular Ha8

1

2

High-throughput

0.489

High

331268

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.489

High

334315

TACC2
Transforming acidic coiled-coil-containing protein 2

1

3

High-throughput

0.489

High

706281

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

814850

CUX1
Homeobox protein cut-like 1

1

1

High-throughput

0.489

High

883942

CENPF
Centromere protein F

1

3

High-throughput

0.489

High

1010870

TMF1
TATA element modulatory factor

1

2

High-throughput

0.489

High

1033419

CDR2
Cerebellar degeneration-related protein 2

1

1

High-throughput

0.489

High

1091033

BFSP1
Filensin

1

3

High-throughput

0.489

High

1097877

STX5
Syntaxin-5

1

1

High-throughput

0.489

High

1217905

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

3

High-throughput

0.489

High

1247752

NHS
Actin remodeling regulator NHS

1

3

High-throughput

0.489

High

1277618

K1C27
Keratin, type I cytoskeletal 27

1

1

High-throughput

0.489

High

1310165

GCC2
GRIP and coiled-coil domain-containing protein 2

1

4

High-throughput

0.489

High

1323336

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

1

High-throughput

0.489

High

1324657

AGGF1
Angiogenic factor with G patch and FHA domains 1

1

1

High-throughput

0.489

High

1326321

NIN
Ninein

1

4

High-throughput

0.489

High

1350430

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.489

High

1350709

CCHCR
Coiled-coil alpha-helical rod protein 1

1

2

High-throughput

0.489

High

1353012

SNX29
Sorting nexin-29

1

2

High-throughput

0.489

High

1388629

SPDLY
Protein Spindly

1

2

High-throughput

0.489

High

1403328

RUFY1
RUN and FYVE domain-containing protein 1

1

2

High-throughput

0.489

High

1410523

TARA
TRIO and F-actin-binding protein

1

1

High-throughput

0.489

High

1410528

EMAL4
Echinoderm microtubule-associated protein-like 4

1

1

High-throughput

0.489

High

1410532

KIF15
Kinesin-like protein KIF15

1

1

High-throughput

0.489

High

1410541

IFT80
Intraflagellar transport protein 80 homolog

1

1

High-throughput

0.489

High

1410544

IF172
Intraflagellar transport protein 172 homolog

1

1

High-throughput

0.489

High

1410545

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

1

High-throughput

0.489

High

1410547

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

2

High-throughput

0.489

High

1410548

TNIK
TRAF2 and NCK-interacting protein kinase

1

1

High-throughput

0.489

High

1218097

Q5VU62
TPM3 protein

1

7

High-throughput

0.470

High

901526

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.437

High

257171

CCD22
Coiled-coil domain-containing protein 22

1

3

High-throughput

0.407

High

324201

CE152
Centrosomal protein of 152 kDa

1

3

High-throughput

0.407

High

464203

TPM2
Tropomyosin beta chain

1

7

High-throughput

0.407

High

686859

S10A4
Protein S100-A4

1

1

High-throughput

0.407

High

995468

TPM4
Tropomyosin alpha-4 chain

1

7

High-throughput

0.407

High

1307484

MY18B
Unconventional myosin-XVIIIb

1

1

High-throughput

0.407

High

1410550

NEB1
Neurabin-1

1

3

High-throughput

0.407

High

1410551

EXOC7
Exocyst complex component 7

5

0

High-throughput

0.374

High

1397098

CEP19
Centrosomal protein of 19 kDa

4

0

High-throughput

0.368

High

1313688

IFT20
Intraflagellar transport protein 20 homolog

3

0

High-throughput

0.360

High

1389789

DTBP1
Dysbindin

4

0

High-throughput

0.360

High

1410533

EXOC1
Exocyst complex component 1

4

0

High-throughput

0.359

High

1197777

CD046
Renal cancer differentiation gene 1 protein

3

0

High-throughput

0.352

High

1347718

ZN417
Zinc finger protein 417

3

0

High-throughput

0.352

High

1348460

LNX1
E3 ubiquitin-protein ligase LNX

3

0

High-throughput

0.348

High

1361573

ING5
Inhibitor of growth protein 5

3

0

High-throughput

0.348

High

1390150

MCRS1
Microspherule protein 1

3

0

High-throughput

0.348

High

1410527

MOB1A
MOB kinase activator 1A

3

0

High-throughput

0.348

High

1410531

ZC4H2
Zinc finger C4H2 domain-containing protein

3

0

High-throughput

0.347

High

1150165

TCEA2
Transcription elongation factor A protein 2

3

0

High-throughput

0.341

High

1227350

A16L1
Autophagy-related protein 16-1

3

0

High-throughput

0.339

High

1351582

MIPT3
TRAF3-interacting protein 1

3

0

High-throughput

0.337

High

137269

EXOC5
Exocyst complex component 5

2

0

High-throughput

0.335

High

1136489

FL2D
Pre-mRNA-splicing regulator WTAP

2

0

High-throughput

0.328

High

1331424

MB213
Protein mab-21-like 3

2

0

High-throughput

0.316

High

1239923

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.313

High

1246155

TRAF7
E3 ubiquitin-protein ligase TRAF7

2

0

High-throughput

0.313

High

1308813

NAV2
Neuron navigator 2

2

0

High-throughput

0.313

High

1322437

SPICE
Spindle and centriole-associated protein 1

2

0

High-throughput

0.313

High

1350555

NEK9
Serine/threonine-protein kinase Nek9

2

0

High-throughput

0.313

High

1382575

EXOC4
Exocyst complex component 4

2

0

High-throughput

0.313

High

1400912

VPS35
Vacuolar protein sorting-associated protein 35

2

0

High-throughput

0.313

High

1406253

KIF2C
Kinesin-like protein KIF2C

2

0

High-throughput

0.313

High

1410516

BEGIN
Brain-enriched guanylate kinase-associated protein

2

0

High-throughput

0.313

High

1410522

ATG5
Autophagy protein 5

2

0

High-throughput

0.313

High

1410540

RAI14
Ankycorbin

2

0

High-throughput

0.313

High

1410543

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.313

High

1127826

KRT81
Keratin, type II cuticular Hb1

1

0

High-throughput

0.304

High

1410546

RABX5
Rab5 GDP/GTP exchange factor

1

0

High-throughput

0.304

High

556948

MYH7
Myosin-7

1

0

High-throughput

0.299

High

749122

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.299

High

1366121

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

0

High-throughput

0.299

High

1386277

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.299

High

1407508

GDIR3
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.299

High

286717

STX11
Syntaxin-11

1

0

High-throughput

0.282

High

664399

ZBT25
Zinc finger and BTB domain-containing protein 25

1

0

High-throughput

0.282

High

900483

FXR2
RNA-binding protein FXR2

1

0

High-throughput

0.282

High

1033190

EWS
RNA-binding protein EWS

1

0

High-throughput

0.282

High

1256878

NUD18
8-oxo-dGDP phosphatase NUDT18

1

0

High-throughput

0.282

High

1328394

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.282

High

1347370

LMO3
LIM domain only protein 3

1

0

High-throughput

0.282

High

1387098

RN183
E3 ubiquitin-protein ligase RNF183

1

0

High-throughput

0.282

High

1410520

NIF3L
NIF3-like protein 1

1

0

High-throughput

0.282

High

1410537

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

0

High-throughput

0.282

High

1410549

DP13A
DCC-interacting protein 13-alpha

1

0

High-throughput

0.282

High

219225

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.279

Low

270116

TMCC2
Transmembrane and coiled-coil domains protein 2

1

0

High-throughput

0.279

Low

317668

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.279

Low

507344

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

0

High-throughput

0.279

Low

572165

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.279

Low

851407

PRS6B
26S proteasome regulatory subunit 6B

1

0

High-throughput

0.279

Low

896296

PEX5
Peroxisomal targeting signal 1 receptor

1

0

High-throughput

0.279

Low

1026524

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.279

Low

1081827

LTOR4
Ragulator complex protein LAMTOR4

1

0

High-throughput

0.279

Low

1179845

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1198514

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.279

Low

1200067

EIPR1
EARP and GARP complex-interacting protein 1

1

0

High-throughput

0.279

Low

1211614

TEX35
Testis-expressed protein 35

1

0

High-throughput

0.279

Low

1212968

STXB5
Syntaxin-binding protein 5

1

0

High-throughput

0.279

Low

1271988

CENPQ
Centromere protein Q

1

0

High-throughput

0.279

Low

1290334

MYPOP
Myb-related transcription factor, partner of profilin

1

0

High-throughput

0.279

Low

1383233

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.279

Low

1398752

PLD3A
PRELI domain containing protein 3A

1

0

High-throughput

0.279

Low

1405208

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.279

Low

1410518

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.279

Low

1410524

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

High-throughput

0.279

Low

1410525

CENPH
Centromere protein H

1

0

High-throughput

0.279

Low

1410529

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

0

High-throughput

0.279

Low

1410530

PRD11
PR domain-containing protein 11

1

0

High-throughput

0.279

Low

1410535

IFT57
Intraflagellar transport protein 57 homolog

1

0

High-throughput

0.279

Low

1410538

USE1
Vesicle transport protein USE1

1

0

High-throughput

0.279

Low

1410542

HOP2
Homologous-pairing protein 2 homolog

1

0

High-throughput

0.279

Low

1410552

EXC6B
Exocyst complex component 6B

1

0

High-throughput

0.279

Low

1410554

RBGP1
Rab GTPase-activating protein 1

1

0

High-throughput

0.279

Low

1410555

SKAP
Small kinetochore-associated protein

1

0

High-throughput

0.279

Low

967536

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.269

Low

1410539

ITSN2
Intersectin-2

1

0

High-throughput

0.251

Low

1091836

TP4A2
Protein tyrosine phosphatase type IVA 2

1

0

Small-scale

0.249

Low

1396568

C170L
Cep170-like protein

1

0

High-throughput

0.238

Low

133790

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.232

Low

251318

NEMF
Ribosome quality control complex subunit NEMF

1

0

High-throughput

0.232

Low

1009876

NUCB2
Nucleobindin-2

1

0

High-throughput

0.232

Low

1167107

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

1258680

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.232

Low

1410534

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025