Protein: DEN10
DENN domain-containing protein 10 (Protein FAM45A)

Gene: DEN10, DENND10
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q8TCE6

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005770 - late endosome
GO:0015031 - protein transport
GO:0031267 - small GTPase binding
GO:0032509 - endosome transport via multivesicular body sorting pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

257149

CCD22
Coiled-coil domain-containing protein 22

7

0

High-throughput

0.714

High

1201140

CCD93
Coiled-coil domain-containing protein 93

6

0

High-throughput

0.705

High

1328832

COMD1
COMM domain-containing protein 1

5

0

High-throughput

0.684

High

1349638

VPS29
Vacuolar protein sorting-associated protein 29

5

0

High-throughput

0.684

High

1277145

VP35L
VPS35 endosomal protein-sorting factor-like

4

0

High-throughput

0.658

High

1349641

COMDA
COMM domain-containing protein 10

3

5

High-throughput

0.604

High

1238019

DE10B
Putative DENN domain-containing protein 10 B

1

0

High-throughput

0.426

High

1349637

COMD3
COMM domain-containing protein 3

6

0

High-throughput

0.378

High

1349634

COMD4
COMM domain-containing protein 4

5

0

High-throughput

0.373

High

1278352

COMD6
COMM domain-containing protein 6

5

0

High-throughput

0.372

High

1293489

COMD2
COMM domain-containing protein 2

4

0

High-throughput

0.363

High

171094

VP26C
Vacuolar protein sorting-associated protein 26C

4

0

High-throughput

0.358

High

1291790

COMD7
COMM domain-containing protein 7

4

0

High-throughput

0.358

High

1349636

COMD9
COMM domain-containing protein 9

4

0

High-throughput

0.358

High

1349633

COMD5
COMM domain-containing protein 5

3

0

High-throughput

0.345

High

1349635

COMD8
COMM domain-containing protein 8

3

0

High-throughput

0.345

High

1349631

PAQR1
Adiponectin receptor protein 1

2

0

High-throughput

0.328

High

251464

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

1

0

High-throughput

0.279

Low

582106

PGAM2
Phosphoglycerate mutase 2

1

0

High-throughput

0.279

Low

1179822

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1243424

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.279

Low

1315644

RN168
E3 ubiquitin-protein ligase RNF168

1

0

High-throughput

0.279

Low

1340034

O13G1
Olfactory receptor 13G1

1

0

High-throughput

0.279

Low

1349629

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.279

Low

1349630

STMN2
Stathmin-2

1

0

High-throughput

0.279

Low

1349632

ODAD1
Outer dynein arm-docking complex subunit 1

1

0

High-throughput

0.279

Low

1349639

ZBT47
Zinc finger and BTB domain-containing protein 47

1

0

High-throughput

0.279

Low

867288

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.249

Low

1254758

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1349640

NISCH
Nischarin

1

0

High-throughput

0.249

Low

423922

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.238

Low

1324547

TM256
Transmembrane protein 256

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025