Protein: COMD6
COMM domain-containing protein 6

Gene: COMD6, COMMD6
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q7Z4G1

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0032088 - negative regulation of NF-kappaB transcription factor activity
GO:0051059 - NF-kappaB binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1278350

COMD1
COMM domain-containing protein 1

10

0

Small-scale

0.932

High

1278372

COMDA
COMM domain-containing protein 10

5

6

Small-scale

0.932

High

1278362

COMD4
COMM domain-containing protein 4

6

0

High-throughput

0.895

High

1278368

COMD3
COMM domain-containing protein 3

4

1

High-throughput

0.892

High

1278345

COMD7
COMM domain-containing protein 7

5

0

Small-scale

0.877

High

1278366

COMD8
COMM domain-containing protein 8

5

0

High-throughput

0.875

High

1278346

COMD2
COMM domain-containing protein 2

4

0

High-throughput

0.853

High

1278361

COMD5
COMM domain-containing protein 5

3

0

High-throughput

0.811

High

257136

CCD22
Coiled-coil domain-containing protein 22

7

0

Small-scale

0.810

High

1278367

COMD9
COMM domain-containing protein 9

7

0

Small-scale

0.805

High

1201129

CCD93
Coiled-coil domain-containing protein 93

6

0

Small-scale

0.798

High

282741

E2F6
Transcription factor E2F6

4

0

High-throughput

0.670

High

171084

VP26C
Vacuolar protein sorting-associated protein 26C

4

0

High-throughput

0.667

High

1122838

TFDP1
Transcription factor Dp-1

3

0

High-throughput

0.646

High

1045449

TF65
Transcription factor p65

2

1

Small-scale

0.611

High

1278363

VP33B
Vacuolar protein sorting-associated protein 33B

2

0

High-throughput

0.602

High

1278344

COMD6
COMM domain-containing protein 6

1

0

Small-scale

0.586

High

600845

HSP76
Heat shock 70 kDa protein 6

2

0

High-throughput

0.580

High

789155

NUP62
Nuclear pore glycoprotein p62

2

0

High-throughput

0.576

High

626271

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

Small-scale

0.536

High

1278347

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

1

High-throughput

0.536

High

1278374

R4GMX3
Polycomb complex protein BMI-1

1

2

High-throughput

0.514

High

175717

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

High-throughput

0.513

High

285976

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

925941

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.513

High

1065264

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1105327

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.513

High

1243417

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.513

High

1274019

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.513

High

1278348

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

0

High-throughput

0.513

High

1278349

KIF2B
Kinesin-like protein KIF2B

1

0

High-throughput

0.513

High

1278353

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

1278354

STMN2
Stathmin-2

1

0

High-throughput

0.513

High

1278355

CCD97
Coiled-coil domain-containing protein 97

1

0

High-throughput

0.513

High

1278357

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.513

High

1278370

RBMX2
RNA-binding motif protein, X-linked 2

1

0

High-throughput

0.513

High

1278371

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.513

High

1278373

DNM3A
DNA

1

0

High-throughput

0.513

High

765662

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.479

High

1278364

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

0

Small-scale

0.460

High

934796

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1278352

DEN10
DENN domain-containing protein 10

5

0

High-throughput

0.372

High

1278369

VPS29
Vacuolar protein sorting-associated protein 29

5

0

High-throughput

0.372

High

1277139

VP35L
VPS35 endosomal protein-sorting factor-like

4

0

High-throughput

0.363

High

935684

MFAP3
Microfibril-associated glycoprotein 3

2

0

High-throughput

0.328

High

1243685

EMB
Embigin

2

0

High-throughput

0.328

High

1099414

SRSF6
Serine/arginine-rich splicing factor 6

1

0

High-throughput

0.279

Low

1180453

C19L2
CWF19-like protein 2

1

0

High-throughput

0.279

Low

1278351

O13G1
Olfactory receptor 13G1

1

0

High-throughput

0.279

Low

1278356

SPF45
Splicing factor 45

1

0

High-throughput

0.279

Low

1278358

ODAD1
Outer dynein arm-docking complex subunit 1

1

0

High-throughput

0.279

Low

1278360

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.279

Low

1278365

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.279

Low

867245

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.249

Low

1278359

SCLT1
Sodium channel and clathrin linker 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025