Protein: ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDE1B) (BCKDH E1-beta)

Gene: ODBB, BCKDHB
Organism: Homo sapiens
Interactions: 45
UniProt ID: P21953

Gene Ontology (top 5):
GO:0003863 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520685

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

6

15

Small-scale

0.953

High

505935

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

2

8

High-throughput

0.811

High

602407

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

5

0

High-throughput

0.688

High

417805

DPOLB
DNA polymerase beta

3

1

High-throughput

0.667

High

602396

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

0

High-throughput

0.602

High

602400

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

135366

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

2

High-throughput

0.536

High

602390

S10A4
Protein S100-A4

1

1

High-throughput

0.536

High

602397

CUL3
Cullin-3

1

2

High-throughput

0.536

High

602405

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

602410

SYMM
Methionine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

602416

HDAC6
Histone deacetylase 6

1

3

High-throughput

0.536

High

602418

DPOLL
DNA polymerase lambda

1

1

High-throughput

0.536

High

581423

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.513

High

602398

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

602406

TTC5
Tetratricopeptide repeat protein 5

1

0

High-throughput

0.513

High

410548

CD1A
T-cell surface glycoprotein CD1a

1

1

High-throughput

0.489

High

602391

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

499526

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

602389

SP100
Nuclear autoantigen Sp-100

1

1

High-throughput

0.479

High

602394

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

602399

PDK1
[Pyruvate dehydrogenase

1

6

High-throughput

0.479

High

602409

OPTN
Optineurin

1

2

High-throughput

0.479

High

602412

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

4

High-throughput

0.479

High

602414

NMRL1
NmrA-like family domain-containing protein 1

1

1

High-throughput

0.479

High

602417

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

602420

TRI33
E3 ubiquitin-protein ligase TRIM33

1

5

High-throughput

0.479

High

279276

DNJB5
DnaJ homolog subfamily B member 5

1

2

High-throughput

0.437

High

602392

LTK
Leukocyte tyrosine kinase receptor

1

2

High-throughput

0.437

High

602395

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.437

High

602402

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

602419

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

602413

GCP60
Golgi resident protein GCP60

1

0

Small-scale

0.426

High

230575

KATIP
Katanin-interacting protein

1

1

High-throughput

0.407

High

602401

CP135
Centrosomal protein of 135 kDa

1

2

High-throughput

0.407

High

602403

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

1

High-throughput

0.407

High

66643

ZN785
Zinc finger protein 785

2

0

High-throughput

0.328

High

602411

TCF25
Ribosome quality control complex subunit TCF25

2

0

High-throughput

0.328

High

380356

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.279

Low

602393

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

0

High-throughput

0.279

Low

602404

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.279

Low

602415

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

319117

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

602408

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

2091

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024